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H. Jack West, MD
Medical Director, Thoracic Oncology Program, Swedish Cancer Institute, Seattle, WA; CEO, Global Resource for Advancing Cancer Education (GRACE)

New Treatment Combination Benefited Patients With Lung Cancer

(AACR) July 29, 2014 - A combination of the EGFR-targeted anticancer therapeutics afatinib (Gilotrif) and cetuximab (Erbitux) yielded clinical responses in 29 percent of patients who had lung cancer harbouring epidermal growth factor receptor (EGFR) mutations that had stopped responding to the EGFR inhibitors erlotinib (Tarceva) and gefitinb (Iressa), according to data from a phase Ib clinical trial.

Commentary: While this work is promising, it's no longer very new, having been presented at major medical meetings more than...



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ALTTO Fallout Focuses Debate on the Meaning of pCR

(Medscape Medical News) July 29, 2014 - This summer, results from the Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization (ALTTO) trial sparked a controversy that is gathering momentum.
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Stivarga (regorafenib) from Bayer Approved in the European Union for the Treatment of Gastrointestinal Stromal Tumors

(Bayer) July 30, 2014 – The oncology compound Stivarga® (regorafenib) from Bayer has been approved by the European Commission (EC) for the treatment of adult patients with unresectable or metastatic gastrointestinal stromal tumors (GIST) who progressed on or are intolerant to prior treatment with imatinib and sunitinib.
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Getting Hospice Care Shouldn't Have To Mean Giving Up

(NPR Shots blog/Kaiser Health News) July 29, 2014 - It's a painful dilemma for seriously ill Medicare patients: To receive the extra support, counseling and care provided by the program's hospice benefit, they have to agree to stop receiving curative treatment for their disease.
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News Story Commentary By Academic and Community Oncologists



New Treatment Combination Benefited Patients With Lung Cancer (AACR)

While this work is promising, it's no longer very new, having been presented at major medical meetings more than...posted by: H. Jack West, MD

U.S. Paves Way for Novartis to Copy Amgen Biotech Drug (Reuters)

The first test for the BioSimilar process. The question is just how much cheaper will the product be? Sandoz...posted by: Winston, Wong, PharmD

Cancer Blood Test Moves Closer After Promising Results (BBC News)

Detailsposted by: Paul Brown Ph.D.

FDA Staff Questions Prostate Cancer Device Effectiveness (Bloomberg)

For localized prostate cancer, there have been various non-radiotherapy, non-surgery approaches, including cryotherapy,...posted by: Howard Sandler, MD, MS, FASTRO

HHS Reissues Disputed 340B Policy on Orphan-drug Discounts (Modern Healthcare)

The 340 B program continues to be yet another runaway train in the cancer care delivery system. With approximately...posted by: William, McGivney, PhD






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