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Archived News Headlines

We have been archiving all OBR daily news stories since March 2008. Use the box below to search our archives for specific articles and content.

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Op-Ed: When Screening Is Bad For A Woman's Health

(Los Angeles Times) July 19, 2015 - If you haven't gotten this message already, you should heed it now: The benefits of screening for breast cancer are limited. We should be doing fewer screening mammograms, not more.
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ASCO Guidelines: Biomarker Use In Metastatic Breast Ca Treatment

(Physician’s Briefing/HealthDay News) July 21, 2015 —Biomarkers can be used to guide decisions on systemic therapy for women with metastatic breast cancer, according to the American Society of Clinical Oncology Clinical Practice Guideline published online July 20 in the Journal of Clinical Oncology.
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Update on ReLive, Livatag® International Phase III Clinical Trial In HCC

(Onxeo) July 21, 2015 - Onxeo S.A., an innovative company specializing in the development of orphan oncology drugs, updates on the clinical development status of ReLive, the Livatag® phase III trial in the treatment of hepatocellular carcinoma.
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BioMarin Provides Programme Update For Talazoparib In Metastatic Breast Cancer

(European Pharmaceutical Review) July 21, 2015 - BioMarin has provided an update on the ABRAZO Phase 2 study of its poly ADP-ribose polymerase (PARP) inhibitor, talazoparib for the treatment of patients with deleterious germline BRCA 1 or BRCA 2 mutations and locally advanced and/or metastatic breast cancer.
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Genmab Announces Submission of Supplemental Biologics License Application to FDA for Ofatumumab as Maintenance Therapy for Relapsed CLL

(StreetInsider) July 22, 2015 — Genmab A/S announced today that a supplemental Biologics License Application (sBLA) has been submitted to the U.S. Food and Drug Administration (FDA) for the use of ofatumumab (Arzerra®) as maintenance therapy of patients with relapsed chronic lymphocytic leukemia (CLL). The application was submitted by Novartis under our ofatumumab collaboration.
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Sound Waves Gently Cull Circulating Tumor Cells from Blood Samples

(NIBIB) July 20, 2015 - The new method uses sound, or acoustic waves, similar to the waves in an ultrasound imaging test, to gently separate CTCs from other blood cells without touching the CTCs.
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Bug Out: Killing Common Bacteria May Curb Stomach Cancer, Studies Show

(Fred Hutch News) July 21, 2015 - This bug loves our guts — living silently in most folks, causing ulcers in others — but a new meta-analysis suggests that eliminating it entirely may help prevent stomach cancers.
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Deadly and Distinctive: Cancer Caused By Gene Deletions

(Yale News) July 20, 2015 - A deadly form of T cell lymphoma is caused by an unusually large number of gene deletions, making it distinct among cancers, a new Yale School of Medicine study shows.
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Applying New Jersey’s Risk Factors, Screening Rates to Louisiana Reverses Recent Colorectal Cancer Trends

(American Cancer Society) July 21, 2015 – If Louisiana, which has some of the highest colon cancer incidence and mortality rates in the nation, had the same risk factors, screening uptake, and survival rates as New Jersey, incidence and mortality from the disease would not only drop, they would drop to levels below that of New Jersey, according to a new study.
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More Evidence Smoking Raises Risk Of Death From Breast Cancer

(Reuters Health) July 21, 2015 - Long-time smokers may face an increased risk of death if they develop breast cancer, according to a Japanese study that adds to a growing body of evidence highlighting the lethal effects of cigarettes.
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Anti-NGF Therapy for Cancer Pain: More Research Needed

(Medscape Medical News) July 20, 2015 - Adding a novel anti–nerve growth factor product to opioids for terminally ill patients with inadequately controlled cancer pain did not significantly improve average cancer pain intensity in a phase 2 study, but secondary endpoints were encouraging.
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Pioglitazone Use Not Linked to Bladder Cancer at 10 Years

(Medscape Medical News) July 21, 2015 - The diabetes drug pioglitazone does not appear to be associated with an increased risk of bladder cancer as had been previously suggested, but new data indicate a possible increased risk of prostate and pancreatic cancer.
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Oncolytic Virus Therapy Shows Benefit in Patients with Melanoma

(NCI/Cancer Currents blog) July 21, 2015 - In a phase III clinical trial, an investigational virus-based immunotherapy, talimogene laherparepvec (T-VEC), significantly increased the durable response rate in patients with metastatic melanoma compared with granulocyte-macrophage colony-stimulating factor (GM-CSF).
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Changing Patterns In Survival For U.S. Women With Invasive Breast Cancer

(NCI News Note) July 20, 2015 - Large-scale study helps clarify factors associated with breast cancer survival in women of all ages.
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AstraZeneca Suffers Setback As Drug Fails In Eye Cancer

(Reuters) July 22, 2015 - AstraZeneca's much anticipated cancer drug pipeline suffered a modest blow on Wednesday when the experimental drug selumetinib failed to meet its goal in a late-stage trial for a rare cancer of the eye.
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European Commission Approves Merck’s Anti-PD-1 Therapy, KEYTRUDA® (pembrolizumab), for Both First-line and Previously-treated Patients with Advanced Melanoma

(Merck) July 22, 2015 - Merck, known as MSD outside the United States and Canada, today announced that the European Commission has approved KEYTRUDA® (pembrolizumab), the company’s anti-PD-1 therapy, for the treatment of advanced (unresectable or metastatic) melanoma in adults.
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Bristol-Myers Says HIV Drug Gets FDA Incentives

(ABC News/Associated Press) July 21, 2015 - Bristol-Myers said Tuesday that federal regulators will help speed up development for one of its experimental HIV drugs.
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Amgen Wins First Approval For New Class Of Cholesterol Drugs

(Reuters) July 21, 2015 - Amgen Inc's cholesterol fighting drug was approved by the European Commission, giving the keenly anticipated treatment a head start over a rival drug being developed by Regeneron Pharmaceuticals Inc and Sanofi SA.
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Doctors Say Teen's HIV In Check for 12 Years Without Drugs

(New York Times/Associated Press) July 20, 2015 - An 18-year-old French teen born with the AIDS virus has had her infection under control and nearly undetectable despite stopping treatment 12 years ago — an unprecedented remission, doctors are reporting.
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Novartis CEO Says U.S. Insurance M&A to Crimp Drug Prices

(Bloomberg) July 21, 2015 - Novartis AG Chief Executive Officer Joe Jimenez said the consolidation spree among U.S. health insurers is making it harder for drugmakers to increase prices in a market that has for years been a primary driver of growth for the pharmaceutical industry.
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Report Ranks Nation’s Best Hospitals By Region, Specialty

(Fox News) July 21, 2015 - U.S. News & World Report has ranked Massachusetts General Hospital, the Mayo Clinic, Johns Hopkins Hospital and UCLA Medical Center as the top hospitals in the nation in its annual report released Tuesday.
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Rising U.S. Drug Prices Are Focus of Research Grant

(Wall Street Journal) July 21, 2015 - The Laura and John Arnold Foundation is providing a $5.2 million grant to the Institute for Clinical and Economic Review to expand the group’s research evaluating whether new drugs are worth their price tags.
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A Revolution In How Doctors Are Paid Isn’t Really Changing How Doctors Are Paid

(Washington Post/Wonkblog) July 20, 2015 - A new study published Monday examined how doctors have been making money in this brave new world vs. the status quo, and found pretty negligible differences.
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Argos Therapeutics Announces Formation of Scientific Advisory Board

(Argos Therapeutics) July 21, 2015 - Inaugural members include distinguished oncologists and immunologists to provide perspectives in research and development of individualized immunotherapies for the treatment of cancer.
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MD Anderson Regains Top Cancer-Care Ranking

(Houston Chronicle) July 20, 2015 - M.D. Anderson Cancer Center has regained the No. 1 designation for cancer care in U.S. News & World Report's annual rankings of hospitals, a year after a drop to No. 2 ended seven straight years atop the list.
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