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Smoking Linked To More Cancer Deaths Than Previously Estimated, Study Finds

(KHN Morning Briefing) June 16, 2015 - It's not just lung cancer: A JAMA Internal Medicine study attributes cigarette use to almost half of the 346,000 deaths from 12 different types of cancers -- including esophagus, colon and bladder -- in individuals 35 years of age or older in 2011.
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Cigna Rebuffs Takeover Approach by Anthem: DJ, Citing Sources

(CNBC) June 15, 2015 - Cigna rejected a takeover approach from larger health insurer Anthem, The Wall Street Journal reported Monday, citing sources.
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CVS Buys Target Pharm Biz for $1.9B

(USA Today) June 15, 2015 - Drugstore chain CVS Health will acquire big-box retailer Target's pharmacy and clinic business for $1.9 billion, the companies said Monday.
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Aledade, Which Helps Small Doctors Run Their Practice In The Age Of Obamacare, Raises $30 Million

(Forbes) June 15, 2015 - Aledade’s clients don’t have to rip and replace their electronic health records, as is often the case with hospital-based ACOs.
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FDA to Work With Online Patient Forum to Mine Drug Safety Data

(Bloomberg) June 15, 2015 - The U.S. Food and Drug Administration is turning to a patient-networking website to get a better handle on the side effects of medications.
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FDA: Drug Companies Routinely Hide The Reasons Their Drugs Are Rejected From Investors

(Forbes) June 12, 2015 - Seven times between 2008, and 2013, the FDA declined to approve a new drug because patients on it were more likely to die. Yet only one company told investors about that concern.
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Quality-of-life Care May Help Cancer Patients Live Longer, Feel Better

(Los Angeles Times) June 12, 2015 - For cancer patients, focus on quality of life could also add to quantity of life; for cancer patients, 'palliative care makes you feel better and helps you live longer,' doctor says.
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Prominent Pediatric Oncologist, Robert Arceci, Dies in Accident

(Medscape Medical News) June 12, 2015 - Prominent pediatric oncologist Robert J. Arceci, MD, PhD, from Phoenix Children's Hospital in Arizona, was killed June 8 in a motorcycle accident while on his way to work.
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Patent Awarded to KSU Preclinical Cancer Detection Test Platform

(KSU) June 15, 2015 - A U.S. patent has been awarded to a Kansas State University technology that quickly detects the early stages of cancer before physical symptoms ever appear.
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Castle Biosciences Announces National Payer Agreements with MultiPlan, FedMed and Preferred Medical Claim Solutions

(Yahoo! Finance) June 15, 2015 - Castle Biosciences, Inc., a provider of molecular diagnostics to improve cancer treatment decisions, today announced the Company has secured payer contracts with national provider networks MultiPlan, Inc., FedMed, Inc. and Preferred Medical Claim Solutions, LLC to provide coverage of its DecisionDx™ assays.
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Weill Cornell Medical College and NewYork-Presbyterian Hospital to Introduce Electronic Informed Consent into its Cancer Clinics

(PRWEB) June 15, 2015 - The Joint Clinical Trials Office of Weill Cornell Medical College and NewYork-Presbyterian Hospital has signed an agreement with Mytrus to develop a pilot project introducing e-Consent technology into the oncology clinics at NewYork-Presbyterian/Weill Cornell Medical Center.
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Atara Biotherapeutics Exercises Exclusive License to T-Cell Technology From Memorial Sloan Kettering Cancer Center

(Atara Bio) June 15, 2015 - Atara Biotherapeutics, Inc. today announced that it has exercised its exclusive option with Memorial Sloan Kettering Cancer Center to license certain clinical stage, allogeneic T-cell therapies for the treatment of cancers and persistent viral infections.
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Geron Corp Announces Receipt of FDA Orphan Drug Designation for Imetelstat as Myelofibrosis Treatment

(StreetInsider) June 15, 2015 - On June 11, 2015, the United States Food and Drug Administration (the “FDA”) granted orphan-drug designation to imetelstat for the treatment of myelofibrosis.
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Advaxis Submits Special Protocol Assessment Request to FDA for ADXS-HPV Phase 3 Clinical Trial in Cervical Cancer

(MarketWatch) June 15, 2015 - Advaxis, Inc. today announced the company has submitted a Special Protocol Assessment (SPA) request to the U.S. Food and Drug Administration (FDA) to initiate detailed design discussions for a Phase 3 clinical study of ADXS-HPV for the treatment of high-risk, locally advanced cervical cancer (HRLACC).
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Ventana Receives FDA Approval for the First Fully Automated IHC Companion Diagnostic to Identify Lung Cancer Patients Eligible for XALKORI® (crizotinib)

(Roche) June 15, 2015 - Ventana Medical Systems, Inc., a member of the Roche Group, today announced approval of the VENTANA ALK (D5F3) CDx Assay by the US Food and Drug Administration (FDA) as a companion diagnostic to aid in the identification of patients for Pfizer's FDA approved targeted therapy, XALKORI® (crizotinib).
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The European Union Must Deliver Funding for Research of Blood Disorders

(EHA) June 12, 2015 - At the Congress of the European Hematology Association (EHA) – attracting 10,000 hematologists from Europe and beyond - the president of EHA, Prof. Christine Chomienne, called upon the European Union to deliver funding for Research into Blood Disorders: “The hematologists in Europe have done a great work. Now it’s the EU’s turn to deliver.”
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Scientists Find Way to Disrupt Brain Tumour Stem Cells

(Toronto Sun) June 15, 2015 - A group of U.S. scientists say they have discovered a way to attack the root of some of the deadliest brain tumours.
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Study Links Gene to Aggressive Form of Brain Cancer

(Institute of Cancer Research [UK]) June 12, 2015 - Scientists have identified a gene mutation linked to the development of an aggressive form of brain cancer.
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Tattoos Mistaken as Cancer Metastases, Surgery Performed

(Medscape Medical News) June 15, 2015 - Physicians should be aware that tattoo ink can look like the spread of cancer to the lymph nodes on diagnostic imaging — and unnecessary treatment can result.
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ALK1 Protein May Play a Role in Breast Cancer Metastasis

(AACR) June 15, 2015 - Breast cancer patients with high levels of the protein activin-like receptor kinase (ALK1) in the blood vessels of their tumors were more likely to develop metastatic disease, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.
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Blood Antibodies May Predict HPV-positive Oropharyngeal Cancer Survival

(AACR) June 15, 2015 - The presence of certain human papillomavirus (HPV)-16 antibodies in the blood was associated with improved rates of survival among patients with HPV-related oropharyngeal carcinoma, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.
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Bluebird Sickle Cell Gene Therapy Results Keep Getting Better

(TheStreet) June 13, 2015 - Six months after infusion with the Bluebird gene therapy known as LentiGlobin, almost half of the oxygen-carrying red blood cells in a single patient are normal and functioning.
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First Randomized Evidence for Kinase Inhibitor Activity in Acute Myeloid Leukemia

(EHA) June 12, 2015 – Dr Ehninger will present the results of a phase II randomized study on the safety and efficacy of Sorafenib.
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Does the Patient with Myelofibrosis Feel Better Through Pacritinib?

(EHA) June 12, 2015 – Dr Mesa will present new data from the phase 3 PERSIST-1 study on improving disease symptoms and quality of life for patients with myelofibrosis.
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New GFI1B Variants in Bleeding and Platelet Disorders

(EHA) June 12, 2015 – Dr Marneth will discuss the findings of eight new genetic variants in GFI1B that have been discovered in patients with bleeding and platelet disorders and consequences for new therapeutic targets.
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