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Patient-Reported Data Indicates That Radiation Therapy Does Not Increase Risk of Lymphedema in Node-Negative Breast Cancer Patients

(ASTRO) Sept 14, 2014 - A secondary analysis of the National Surgical Adjuvant Breast and Bowel Project B-32 trial (Krag 2010) indicates that radiation therapy (RT) does not increase the incidence of lymphedema in patients with node-negative breast cancer, according to research presented today at ASTRO's 56th Annual Meeting.
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Shorter Course of Androgen Deprivation Therapy for High-Risk Prostate Cancer Patients Yields Improved Quality of Life

(ASTRO) Sept 14, 2014 - High-risk prostate cancer patients who receive radiation therapy (RT) and an 18-month course of androgen deprivation therapy (ADT) recover a normal testosterone level in a shorter amount of time compared to those who receive a 36-month course of ADT, thus resulting in a better quality of life (QOL) and without detriment to long-term outcomes, according to research presented today at ASTRO’s 56th Annual Meeting.
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Advanced Esophageal Cancer Patients Who Receive RT Experience Less Problems When Swallowing Compared to Those Who Receive RT With Chemotherapy

(ASTRO) Sept 14, 2014 - Radiation therapy (RT) alone is as effective in decreasing swallowing complications experienced by advanced esophageal cancer patients as RT combined with chemotherapy, thus allowing patients to forgo chemotherapy, according to research presented today at ASTRO’s 56th Annual Meeting.
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Blood Test for VEGF-A, TGF-B1 Prior to Treatment Could Help Determine Tailored Treatment Options for Esophageal Cancer Patients

(ASTRO) Sept 14, 2014 - A blood test may be beneficial in indicating neoadjuvant treatment regimens for patients with esophageal squamous cell carcinoma (ESCC), according to research presented today at ASTRO’s 56th Annual Meeting.
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Chest Radiation Ups Survival in Small-Cell Lung Cancer

(Medscape Medical News) Sept 15, 2014 - In patients with advanced disease who respond to chemotherapy, thoracic radiation improves outcomes, according to a new phase 3 study presented at ASTRO.
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Medical Calculators Use Big Data to Help Patients Make Choices

(Wall Street Journal) Sept 14, 2014 - Doctors are turning to sophisticated clinical calculators that crunch big data to help patients make informed medical decisions.
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Should You Get Cancer Screenings?

(Wall Street Journal) Sept 14, 2014 - Doctors on both sides of the "overdiagnosis" debate increasingly say patients should decide for themselves after consulting with a physician.
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Some Cancer Experts See 'Overdiagnosis,' Question Emphasis on Early Detection

(Wall Street Journal) Sept 14, 2014 - Some of the nation's top cancer experts say zealous screening and advanced diagnostic tools are encouraging treatments of abnormalities that might never have been life-threatening.
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Drug Shortages

(Health Affairs/Health Policy Briefs) Sept 11, 2014 - Government and private-sector leaders have struggled to address persistent drug shortages driven by complex market forces.
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Sticking Point: The Price of an Old Insulin Skyrockets

(Wall Street Journal/Pharmalot blog) Sept 11, 2014 - Insulin is an old drug, but the price of one of its most concentrated formulations – known as Humulin U-500 – increased more than five times over the last seven years.
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FDA Panel Backs Novo Nordisk Injection For Obesity

(Boston Globe/Associated Press) Sept 12, 2014 - Federal health experts say a diabetes drug from Novo Nordisk should be approved for a new use in treating obesity.
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$250 Billion in Biotech Drug Savings on Brink of Arrival

(Bloomberg) Sept 12, 2014 - At least 14 expensive biotechnology medicines that have never before faced generic rivals in the U.S. are being targeted by drugmakers who want to sell imitations at cheaper prices, according to regulators.
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Proposed Physician Fee Schedule Draws Criticism From Docs, Insurers

( Sept 11, 2014 - Stakeholders from across the healthcare continuum are raising red flags about provisions of Medicare's proposed physician fee schedule for 2015, including quality incentives and reporting for physicians, a new reimbursement code for chronic-disease management and a fact-finding initiative.
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Prostate Cancer Foundation Awards $6.1 Million to 2014 Young Investigators, Jumpstarting Careers of Promising MDs and PHDs

(PCF) Sept 11, 2014 - The Prostate Cancer Foundation (PCF) has awarded 27 new Young Investigator Awards selected from 16 countries to advance new drug discovery, immunotherapy, nutritional sciences, and diagnostics for precision medicine.
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Poster Presentation Opportunity Available for Nation's Top Researchers in Oncology

(NCCN) Sept 12, 2014 - The National Comprehensive Cancer Network® (NCCN®) is now accepting original abstracts for consideration to be presented during the NCCN 20th Annual Conference: Advancing the Standard of Cancer Care™ General Poster Session, March 12-13, 2015, at The Diplomat in Hollywood, Florida.
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Livestrong Takes Hit After Armstrong Confession

(ABC News/Associated Press) Sept 11, 2014 - The Livestrong cancer charity is reporting a sharp drop in donations and revenue after founder Lance Armstrong admitted taking performance-enhancing drugs during most of his record-setting cycling career.
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Proposed: A Scale For Financial AEs and Cancer Treatment

(Medscape Medical News) Sept 11, 2014 - A provocative and novel use of the Common Terminology Criteria for Adverse Events (CTCAE) from the National Cancer Institute has been proposed by a clinician who is concerned about the ill effects of the cost of cancer treatment.
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Immunicum AB: Immunicum Presents Updated Survival Data For INTUVAX-Treated Renal Cancer Patients

(FinanzNachrichten) Sept 12, 2014 - Immunicum AB today announced that updated survival data from a completed Phase I/II study of INTUVAX will be presented on September 15 at the 3rd Annual Cancer Vaccines Conference in London.
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A Non-Toxic Strategy to Treat Leukemia

(Harvard Stem Cell Institute) Sept 11, 2014 - A study comparing how blood stem cells and leukemia cells consume nutrients found that cancer cells are far less tolerant to shifts in their energy supply than their normal counterparts.
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UB Study to Explore Obesity-Aggressive Prostate Cancer Link

(University of Buffalo) Sept 11, 2014 - Wilma A. Hofmann, PhD, assistant professor of physiology and biophysics, will study cellular processes that cause high levels of unsaturated fats to increase the metastatic potential of prostate cancer cells.
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Dartmouth Research Links Genetic Mutation and Melanoma Progression

(The Geisel School of Medicine at Dartmouth) Sept 11, 2014 - Dartmouth researchers have found that the genetic mutation BRAFV600E, frequently found in metastatic melanoma, not only secretes a protein that promotes the growth of melanoma tumor cells, but can also modify the network of normal cells around the tumor to support the disease's progression.
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NCI Study Examines Outcomes From Surgery to Prevent Ovarian Cancer

(NCI News Note) Sept 8, 2014 - A new study looked at women at high risk of ovarian cancer who had no clinical signs of the disease and who underwent risk-reducing salpingo-oophorectomy (RRSO).
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Merck KGaA Ends Lung Cancer Vaccine Trials

(Reuters) Sept 12, 2014 - German drugmaker Merck KGaA drug stopped all remaining clinical studies of the experimental lung cancer vaccine tecemotide, formerly known as Stimuvax, after renewed attempts to show its effectiveness failed.
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Lilly Stomach Cancer Drug Prolongs Life in Colon Cancer Study

(Reuters) Sept 12, 2014 - Eli Lilly and Co's Cyramza stomach-cancer drug prolonged survival of patients with advanced colon cancer in a late-stage study, the U.S. drugmaker said on Friday.
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Lilly Announces CYRAMZA™ Phase III Second-Line Colorectal Cancer Trial Meets Primary Endpoint of Overall Survival

(Lilly) Sept 12, 2014 - Eli Lilly and Company today announced that the RAISE trial, a Phase III study of ramucirumab (CYRAMZA™) in combination with chemotherapy in patients with metastatic colorectal cancer (mCRC), met its primary endpoint of overall survival.
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