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Archived News Headlines

We have been archiving all OBR daily news stories since March 2008. Use the box below to search our archives for specific articles and content.

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New Research From Hebrew University Reveals New Implications For Fighting Cancer

(AFHU [Israel]) Jan 22, 2015 - New research from The Hebrew University of Jerusalem shows that the most common form of white blood cells, called neutrophils, contain many different subtypes, of which some fight the development of cancer and others promote its progression.
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Key Factor Discovered in the Formation of Metastases in Melanoma

(University of Zurich [Switzerland]) Jan 22, 2015 - Researchers from the University of Zurich now reveal that so-called epigenetic factors play a role in the formation of metastases in malignant skin cancer. This opens up new possibilities for future cancer treatments.
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Early Results of Cancer Vaccine Trial in Singapore Look Promising

(Channel Asia [Singapore]) Jan 21, 2015 - There has been a promising breakthrough in cancer research, as a vaccine trial being conducted in Singapore shows no major side effects on the four patients with Stage 4 cancer. This is the first time it is being tested in humans.
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Sunitinib Active in Advanced Thymic Carcinoma

(Medscape Medical News) Jan 22, 2015 - Sunitinib is active in advanced thymic carcinoma, concludes the first clinical trial of the drug in heavily pretreated patients.
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Complete Mesocolic Surgery Improves Outcomes in Colon Cancer

(Medscape Medical News) Jan 22, 2015 - Complete mesocolic excision, a new way of performing surgery in patients with stage I-III colon cancer, is shown to improve disease-free survival. So why are we waiting?
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Cancer Dogma Overturned?

(San Diego Union-Tribune) Jan 22, 2015 - Challenging a long-held dogma about cancer, a new study finds that enzymes long believed to promote cancer actually suppress it.
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The People Who Brought You Cheaper Hepatitis C Drugs Are Going After Cancer Next

(Bloomberg) Jan 22, 2015 - Express Scripts Holding Co., which this year forced price concessions from makers of $1,000-a-day hepatitis C medicines, has set its sights on $37 billion in U.S. spending on cancer medications. Its goal is to start influencing the drugs’ costs as soon as next year.
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Drugs’ Path to China Slows as Regulatory Delays Add Up, J&J Says

(Bloomberg) Jan 21, 2015 - The Chinese pharmaceutical market is becoming increasingly challenging for drug companies because of how long regulators there take to approve new medicines, Johnson & Johnson’s Chief Scientific Officer Paul Stoffels said.
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Counterfeit Cialis Found Entering U.S. By Mail: FDA

(Reuters) Jan 21, 2015 - The U.S. Food and Drug Administration said counterfeit versions of the erectile dysfunction drug Cialis were found in the mail en route to a customer in the United States, and it is alerting consumers and doctors to be on the lookout for fakes.
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Docs Urge Big Changes to Health Records Program

(The Hill) Jan 21, 2015 - A coalition of 35 medical societies is urging federal regulators to make major changes to the Meaningful Use electronic health records (EHR) program.
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Predictable Fault Lines Emerge as Perennial Doc-Fix Debate Begins

(Modern Healthcare) Jan 21, 2015 - There's only one outstanding issue left to resolve before Congress can pass a permanent “doc fix”: how to cover the roughly $140 billion price tag.
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1,700 Hospitals Win Quality Bonuses From Medicare, But Most Will Never Collect

(Kaiser Health News) Jan 22, 2015 - Medicare is giving bonuses to a majority of hospitals that it graded on quality, but many of those rewards will be wiped out by penalties the government has issued for other shortcomings, federal data show.
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Curis, Aurigene Partner to Develop Precision Oncology Targets

(Pharmaceutical Business Review) Jan 22, 2015 - Curis and Aurigene Discovery Technologies have entered into an exclusive collaboration agreement focused on immuno-oncology and selected precision oncology targets.
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Kite Pharma Announces Expanded Agreement With Tel Aviv Sourasky Medical Center and Pioneering Researcher Professor Zelig Eshhar to Develop Novel Chimeric Antigen Receptor (CAR) Approaches For Cancer Immunotherapy

(CNBC) Jan 22, 2015 - Kite Pharma, Inc today announced that the Company has expanded its agreement with Tel Aviv Sourasky Medical Center to research and develop novel approaches to CAR T-cell therapy, the technology underlying Kite's most advanced programs in cancer immunotherapy.
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UK Start-Up Autolus Enters CAR-T Cancer Race

(PharmaTimes [UK]) Jan 22, 2015 - Backed with £30 million from healthcare investment group Syncona and following major support from the UK government, University College London has created Autolus to develop CAR T-cell products to fight cancer.
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Ventana Seeks FDA Premarket Approval for Lung Cancer CDx

(GenomeWeb) Jan 21, 2015 - Ventana Medical Systems, a Roche business, today announced it has submitted the ALK (D5F3) CDx Assay to the US Food and Drug Administration for premarket approval.
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Celgene, Biotech's Ace Dealmaker, Bets on Canada's Zymeworks

(Forbes) Jan 21, 2015 - Celgene, the big maker of blood cancer drugs, has gained a reputation for anointing biotech startups before they break out. Now it’s betting on a little Canadian biotech, Zymeworks, with technology for engineering new types of targeted antibody drugs.
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ASCO: 'High-Risk' Project 'Must Be Done'

(Medscape Medical News) Jan 22, 2015 - The organization has been claiming that CancerLinQ will revolutionize cancer care for months. Now they have a technology partner to help them.
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Immunomedics Reports Phase 1/2 Results With Sacituzumab Govitecan (IMMU-132) in Patients With Metastatic Gastrointestinal Cancers

(Immunomedics) Jan 20, 2015 - Immunomedics, Inc., today announced that sacituzumab govitecan, the Company’s lead investigational antibody-drug conjugate (ADC), produces partial response (PR) in some patients with metastatic esophageal and colorectal cancers who had been heavily pretreated.
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Enzalutamide Phase 2 Terrain Trial Demonstrated Statistically Significant Increase in PFS as Compared to Bicalutamide in Metastatic Prostate Cancer

(MarketWatch) Jan 22, 2015 - Medivation, Inc. and Astellas Pharma Inc. today announced topline results from the Phase 2 TERRAIN trial comparing enzalutamide with bicalutamide in men with metastatic castration-resistant prostate cancer.
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CytRx Announces Overall Survival Results from Its Global Phase 2b Clinical Trial of Aldoxorubicin in Soft Tissue Sarcoma

(Yahoo! Finance) Jan 22, 2015 – Aldoxorubicin demonstrates 2-fold increase in likelihood of surviving more than 2 years versus doxorubicin and 27% reduction in the risk of death.
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Major Study Links Gene to Drug Resistance in Testicular Cancer

(ICR [UK]) Jan 22, 2015 - A major research study has uncovered several new genetic mutations that could drive testicular cancer – and also identified a gene which may contribute to tumours becoming resistant to current treatments.
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New Cancer-Fighting Strategy Would Harden Cells to Prevent Metastasis

(Johns Hopkins Medicine) Jan 21, 2015 - Existing cancer therapies are geared toward massacring tumor cells, but Johns Hopkins researchers propose a different strategy: subtly hardening cancer cells to prevent them from invading new areas of the body.
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Close Monitoring of Renal Tumors May Provide Alternative to Surgery

(Mount Sinai Hospital) Jan 21, 2015 - In patients with small renal tumors confined to the kidneys, close, active monitoring, as opposed to immediate surgery, is associated with low rates of tumor growth or death, according to a research study.
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Palbociclib For Breast Cancer Inches Toward FDA Approval

(Medscape Medical News) Jan 21, 2015 - Palbociclib, the first CDK 4/6 inhibitor, has shown a doubling of progression-free survival in postmenopausal women with ER-positive, HER2-negative advanced-stage breast cancer.
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