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Archived News Headlines

We have been archiving all OBR daily news stories since March 2008. Use the box below to search our archives for specific articles and content.

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Europe Backs Continued Use of Ariad Pharma's Leukaemia Drug

(Reuters) Oct 24, 2014 - European regulators recommended continued use of Ariad Pharmaceuticals Inc's cancer drug, Iclusig, in its already approved indications to treat certain kinds of leukemia.
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AstraZeneca Ovarian-Cancer Drug Wins EU Agency’s Backing

(Bloomberg) Oct 24, 2014 - AstraZeneca Plc won backing from a European Union regulator for an ovarian-cancer drug, one of the experimental medicines the company cited as a reason for fending off Pfizer Inc.’s $117 billion takeover offer this year.
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Obama Cautiously Optimistic About U.S. Ebola Situation

(Morningstar/Dow Jones Newswires) Oct 22, 2014 - President Barack Obama on Wednesday said he is "cautiously more optimistic" about the Ebola situation in the U.S. as health-care workers and others exposed to an infected patient show signs of recovery or are cleared of the disease.
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Novartis Reports Positive Results in Spinal Inflammation Condition

(Reuters) Oct 23, 2014 - Swiss drugmaker Novartis said on Thursday two late-stage trials showed its drug secukinumab improved symptoms of ankylosing spondylitis, a debilitating joint condition of the spine.
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Regulus Surges on Early Hepatitis C Drug Data

(CNBC/Associated Press) Oct 22, 2014 - Shares of Regulus Therapeutics more than doubled Wednesday as early testing of a hepatitis C drug appeared promising.
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Potential Policy Fixes to Curb Medicare Part D Opioid Abuse

(ASH) Oct 22, 2014 - During the most recent meeting on October 9, MedPAC analyzed data on opioid abuse for Medicare Part D enrollees. Both the findings and potential policy implications could affect practicing hematologists who routinely prescribe opioids.
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Up Next on Congress' Menu: CHIP and SGR

(MedPage Today) Oct 22, 2014 - Once Congress comes back in November from its pre-election recess, members will be considering what to do about two important healthcare policy issues: reauthorizing the Children's Health Insurance Program (CHIP) and repealing and replacing the long-reviled sustainable growth rate (SGR) formula for physician reimbursement under Medicare.
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Dr. Brian Durie, Chairman of the International Myeloma Foundation, Honored by Mayo Clinic With Distinguished Alumni Award

(IMF) Oct 22, 2014 - The International Myeloma Foundation (IMF) – improving the quality of life of myeloma patients while working toward prevention and a cure – congratulates its Chairman and Co-Founder Brian G.M. Durie, MD, on being honored with the Distinguished Alumni Award from Mayo Clinic.
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U.S. Court Upholds Patents on Pfizer's Cancer Drug

(Reuters) Oct 23, 2014 - A U.S. district court ruled in favor of Pfizer Inc in a patent lawsuit it filed against Mylan Inc alleging patent infringement on its cancer drug, Sutent, Pfizer said.
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Eli Lilly Adds $375M to Zymeworks Partnership

(Fox Business/Associated Press) Oct 22, 2014 - Eli Lilly and Zymeworks said Wednesday they are expanding a cancer drug development partnership.
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Sutro Biopharma and Celgene Corporation Enter Multi-Year Strategic Collaboration and Option to Acquire Agreement

(Yahoo! Finance) Oct 23, 2014 - Sutro Biopharma today announced it has entered into a strategic collaboration and option agreement with Celgene Corporation to discover and develop multispecific antibodies and antibody drug conjugates (ADCs).
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Yale and Gilead Sciences Extend Cancer Research Collaboration

(YaleNews) Oct 23, 2014 - The Yale School of Medicine has announced a three-year extension of a research collaboration with Gilead Sciences, Inc., which was formed in 2011 to discover novel cancer therapies.
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NeoGenomics Is First to Offer Molecular Testing For Resistance to Bruton Tyrosin Kinase Inhibitors For Chronic Lymphocytic Leukemia

(Yahoo! Finance) Oct 23, 2014 - NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today that it has launched new tests for the detection of mutations in the Bruton tyrosine kinase (BTK) and PLC-gama2 genes for predicting acquired resistance to BTK inhibitors.
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FDA Guidance on the Use of pCR in Development of New Treatments For High Risk Early Breast Cancer Includes ASCO Suggestions

(ASCO in Action) Oct 22, 2014 - The U.S. Food and Drug Administration’s recently released final Guidance for Industry on Pathological Complete Response in Neoadjuvant Treatment of High-Risk Early-Stage Breast Cancer incorporates two changes that ASCO had proposed in comments submitted to the agency on a draft guidance issued in 2012.
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LungCAN Pressures Medicare to Cover Lung Cancer Screening in New Online Campaign

(Yahoo! Finance) Oct 23, 2014 - Lung Cancer Action Network (LungCAN®) members are encouraging Congress to compel the Centers for Medicare and Medicaid Services (CMS) to cover low-dose CT scans for high-risk seniors.
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Finally: A Missing Link Between Vitamin D and Prostate Cancer

(UCCC/In the Lab blog) Oct 22, 2014 - A University of Colorado Cancer Center study recently published in the journal Prostate offers compelling evidence that inflammation may be the link between Vitamin D and prostate cancer.
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Nanoparticle-Based Invention Moves New Cancer Drugs Closer to Clinical Testing

(Penn State News) Oct 22, 2014 - Penn State College of Medicine researchers have developed a nanoparticle to deliver a melanoma-fighting drug directly to the cancer.
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Fast Modeling of Cancer Mutations

(MIT News) Oct 22, 2014 - New genome-editing technique enables rapid analysis of genes mutated in tumors.
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Genomic Sequencing More Efficient in Predicting Breast Cancer Risk Than Previously Thought

(ACCR) Oct 23, 2014 - Using genomic sequencing data on all currently known genetic alterations in breast cancer, it is possible to identify a woman’s genetic risk for the disease, and this approach can bring greater gains in disease prevention than previously estimated, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
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Castle Biosciences’ Multi-Analyte Test Successfully Identifies Esophageal Cancer Patients Who Are Extremely Resistant to Standard Treatment of Chemoradiation Therapy

(Yahoo! Finance) Oct 23, 2014 - Castle Biosciences Inc. today announced that results from a second validation study of its proprietary multi-analyte test, DecisionDx-EC, confirmed the test’s ability to identify which esophageal cancer patients are unlikely to benefit from the standard pre-surgical treatment of chemoradiation.
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Data Presented at the International Society of Paediatric Oncology (SIOP) Congress Show Palonosetron Is a Valuable Option For Treating Pediatric Patients Receiving Moderately to Highly Emetogenic Chemotherapy

(Yahoo! Finance) Oct 23, 2014 - Helsinn Group, the company focused on building quality cancer care, presented data at the International Society of Paediatric Oncology (SIOP) congress establishing that palonosetron, at a dose 20 g/kg, is a valuable and efficacious treatment option for chemotherapy-induced nausea and vomiting (CINV) in pediatric patients up to 17 years of age.
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Wait on Radiation After Surgery For Glioblastoma

(Medscape Medical News) Oct 22, 2014 - Patients with newly diagnosed glioblastoma multiforme (GBM) have significantly better overall survival when there is a short delay between surgery and the start of radiation therapy, investigators say.
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Experimental Breast Cancer Drug Holds Promise in Combination Therapy For Ewing Sarcoma

(St. Jude) Oct 23, 2014 - Ewing sarcoma tumors disappeared and did not return in more than 70 percent of mice treated with combination therapy that included drugs from a family of experimental agents developed to fight breast cancer, reported St. Jude Children’s Research Hospital scientists.
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New Evidence That Colonoscopy Reduces Cancer Risk, Mortality

(Medscape Medical News) Oct 23, 2014 - Colonoscopy reduces cancer risk and mortality in patients with inflammatory bowel disease, according to the largest study of its kind, presented here at the American College of Gastroenterology (ACG) 2014 Annual Scientific Meeting.
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How Medicare ‘Self-Referral’ Thrives on Loophole

(Wall Street Journal) Oct 22, 2014 - In a letter to a friend, the manager of a Florida urology practice worried in 2010 that her company would attract federal scrutiny for its frequent use of an expensive bladder-cancer test.
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