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Archived News Headlines

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Karyopharm Announces a Phase 1 Trial of Selinexor (KPT-330) in Pediatric Patients with Relapsed Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia

(Benzinga) Apr 21, 2014 - Karyopharm Therapeutics Inc. today announced the initiation of its first pediatric clinical study, a Phase 1 trial of its novel, oral Selective Inhibitor of Nuclear Export (SINE) compound Selinexor (KPT-330) in pediatric patients with relapsed or refractory acute lymphoblastic leukemia.
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Dana-Farber Researchers Uncover Link Between Down Syndrome and Leukemia

(Dana-Farber) Apr 20, 2014 - A team of Dana-Farber Cancer Institute investigators has uncovered a connection between the development of acute lymphoblastic leukemia (ALL) during childhood and Down syndrome.
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Proteins Conspire to Make Breast Cancer Cells Resistant to Drug Treatment

(Sanford-Burnham Science Blog) Apr 18, 2014 - In a recent study, scientists from Sanford-Burnham provide compelling and conclusive evidence that antiestrogen resistance in breast cancer cells requires the interaction between proteins called BCAR1 and BCAR3.
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Drug Combo May Knock Down Lung Cancer

(San Diego Union-Tribune) Apr 20, 2014 - Some drug-resistant cancers of the lung, pancreas and breast might be made vulnerable again by treating them with a medication already approved for another type of cancer, according to a new study led by scientists at UC San Diego.
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New Gene Variant Found that Increases the Risk of Colorectal Cancer From Eating Processed Meat

(Fred Hutchinson) Apr 17, 2014 - A common genetic variant that affects one in three people appears to significantly increase the risk of colorectal cancer from the consumption of processed meat, according to study published today in PLOS Genetics.
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Stanford Scientists Identify Source of Most Cases of Invasive Bladder Cancer

(Stanford School of Medicine) Apr 20, 2014 - A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer, according to researchers at the Stanford University School of Medicine.
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Cholesterol Unlocks Clues to Prostate Cancer Spread

(The University of Manchester [UK]) Apr 16, 2014 - Scientists have uncovered a link between cholesterol and prostate cancer’s ability to spread to the bones in a study published in the British Journal of Cancer today.
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Robot Versus Surgeon: No Clear Winner

(MedPage Today) Apr 18, 2014 - Robot-assisted radical prostatectomy led to complication rates, readmission rates, and rates of additional cancer therapy similar to those of conventional surgical prostatectomy, a review of almost 6,000 cases showed.
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Is There A Link Between Prostate Cancer And Chronic Inflammation?

(Forbes) Apr 21, 2014 - Based on data from a new study from the Johns Hopkins Kimmel Cancer Center, men who demonstrate evidence of chronic inflammation seen in prostate biopsies stemming from chronic prostatitis may have close to twice the risk of developing prostate cancer compared to those without inflammation.
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FDA Approves Ofatumumab for Chronic Lymphocytic Leukemia

(ASCO in Action) Apr 17, 2014 - On April 17, 2014, the U. S. Food and Drug Administration approved ofatumumab (Arzerra® Injection, for intravenous infusion; GlaxoSmithKline) in combination with chlorambucil, for the treatment of previously untreated patients with chronic lymphocytic leukemia (CLL), for whom fludarabine-based therapy is considered inappropriate.
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AstraZeneca Cancer Pipeline Seen as Draw for Pfizer

(Reuters) Apr 21, 2014 - Pfizer may come back to bid for British drug company AstraZeneca after its reported 60 billion pound ($101 billion) takeover approach was rejected, since a deal could make sense for the U.S. pharmaceuticals giant as it seeks to build up its cancer franchise.
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Clinical Trial Of Juno Therapeutics Cell Therapy Restarts

(Forbes) Apr 19, 2014 - Earlier this month, a study of a much-watched cell therapy that genetically modifies patients' immune cells in order to attack tumors was stopped because the treatment may have caused the deaths of two patients. The trial is now once again enrolling patients, according to Juno Therapeutics, the startup that is commercializing the treatment.
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GSK and Genmab Receive FDA Approval for Arzerra (ofatumumab) as First-Line Treatment in Combination with Chlorambucil for Patients with Chronic Lymphocytic Leukemia (CLL) for Whom Fludarabine-Based Therapy Is Considered Inappropriate

(Morningstar) Apr 17, 2014 - Arzerra now approved for use in previously untreated patients for whom fludarabine-based therapy is considered inappropriate; approval based on Phase III data from study with ofatumumab + chlorambucil.
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FDA Warns Against Procedure to Remove Uterine Fibroids; Says It Could Spread Hidden Cancer

(Washington Post) Apr 17, 2014 - The Food and Drug Administration on Thursday took the rare step of urging doctors to stop performing a surgical procedure used on tens of thousands of women each year to remove uterine growths, saying the practice risks spreading hidden cancers within a woman’s body.
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ASCO Calls on CMS to Resolve Medicare Payment Data Issues

(ASCO in Action) Apr 17, 2014 - The American Society of Clinical Oncology (ASCO) is urging the Centers for Medicare & Medicaid Services (CMS) to immediately correct inaccuracies in Medicare physician payment data released last week.
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Six Percent of Colorectal Cancer Found to Be Interval Tumors

(Oncology Nurse Advisor/HealthDay News) Apr 17, 2014 - Six percent of patients with colorectal cancer (CRC) have interval cancers, which develop within six to 60 months of colonoscopy, according to a study published in the April issue of Gastroenterology.
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Ebola Virus in Africa Outbreak Is a New Strain

(USA Today/Associated Press) Apr 16, 2014 - The Ebola virus that has killed scores of people in Guinea this year is a new strain — evidence that the disease did not spread there from outbreaks in some other African nations, scientists report.
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Teva, Pfizer Settle Patent Lawsuit Over Blockbuster Painkiller Celebrex

(Reuters) Apr 17, 2014 - Teva Pharmaceutical Industries Ltd said it settled a patent lawsuit with Pfizer Inc, allowing the Israeli drugmaker to launch a generic version of Pfizer's blockbuster painkiller Celebrex in December.
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VA, California Panels Urge Costly Hepatitis C Drugs For Sickest Patients

(Kaiser Health News) Apr 17, 2014 - Doctors should consider expensive new hepatitis C drugs for patients with advanced liver disease, including those awaiting transplants, but ask most others to wait for drugs in development, the Department of Veterans Affairs said Wednesday.
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Medicare Kept Paying Indicted, Sanctioned Doctors

(NPR/Shots blog) Apr 16, 2014 - Among doctors who received payments from Medicare in 2012 are dozens who had been kicked out of Medicaid, or charged with fraud, or settled fraud cases out of court, a ProPublica investigation finds.
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Teen Makes Genetic Discovery of Her Own Rare Cancer

( Apr 16, 2014 – At age 12, Elana's bright future hit a terrifying hurdle when she was diagnosed with a rare form of liver cancer.
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Letter: Cancer Society and Tobacco

(New York Times) Apr 16, 2014 - To the Editor: Last year, Walgreens customers contributed more than $6 million to help the American Cancer Society provide free cancer screenings, information and support to people who could not otherwise afford them. Every dollar donated at checkout helped prevent or mitigate suffering from cancer.
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ASH Committee on Government Affairs Visits Congress to Discuss Research Funding and Oral Chemotherapy Parity

(ASH) Apr 16, 2014 - Following its April 8 meeting in Washington, DC, the ASH Committee on Government Affairs visited nearly 40 congressional offices on April 9 to explain to Members of Congress and their staff the impact that cuts in funding to the National Institutes of Health (NIH) has on research to find cures and treatments for patients with serious hematologic diseases and the need to continue to support and invest in federal biomedical research funding.
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Under Dr. Rugo's Leadership, 'Giants of Cancer Care' Continues to Grow

(Reuters) Apr 16, 2014 - Record number of nominations now in for 2014 Giants Class, presented by OncLive.
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How Tennessee Oncology Is Getting Patients to Say How They Really Feel

(Nashville Business Journal [blog]) Apr 16, 2014 - Nashville-based Tennessee Oncology wants to know exactly how patients are feeling about their experience – exactly when they’re feeling it.
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