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OBR Finance Top 5 Winners

CERU $5.71 0.6699 +13.29%
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Epigenetic Study Reveals New Insights Into Breast Cancer

(ESMO) May 5, 2011 - The most comprehensive analysis yet of the epigenetic modifications present in breast cancer has revealed potentially important new ways to detect and treat the disease, Belgian researchers have reported.
read press release 

About the Premarin Study and Breast Cancer

(ACP Internist Blog) May 4, 2011 - This week a paper came out in JAMA showing a surprising reduction in breast cancer cases among women who had hysterectomies and then took Premarin, an estrogen-only remedy compounded from steroids in horses' urine.
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Strong Evidence Supports Prognostic Value of Circulating Tumor Cells in Breast Cancer

(ESMO) May 5, 2011 - French researchers have reported the strongest proof yet that evidence of ‘circulating tumor cells’ found in samples of a patient’s blood is strongly linked to poor outcomes such as a short time to disease progression.
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Researcher Maps Far-Reaching Effects of Estrogen Signaling in Breast Cancer Cells

(UT Southwestern) May 5, 2011 - A UT Southwestern Medical Center researcher has identified the most comprehensive measurement to date of estrogen’s effect on breast cancer cells, showing for the first time how immediate and extensive the effect is.
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FDA Approves Test to Identify Candidates for Breast Cancer Drug

(NCI Cancer Bulletin) May 3, 2011 - The Food and Drug Administration (FDA) has approved a genetic test that doctors can use to help identify women with breast cancer who have extra copies of the HER2 gene and therefore may benefit from the drug trastuzumab (Herceptin).
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Einstein Researchers Find Key Gene in Childhood Cancer

(Albert Einstein) May 5, 2011 - There are no effective treatments for rhabdoid tumors – aggressive childhood cancers that usually strike children under three years old and affect the brain or kidneys.
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Childhood Cancer Survivors Are at Increased Risk for Ongoing Post-Therapy GI Complications

(AGA) May 4, 2011 - Patients who received therapy for cancer during childhood have an increased risk of developing gastrointestinal (GI) complications later in life, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute. Compared with their siblings, cancer survivors had an increased risk of late-onset complications of the upper GI tract, lower GI tract and liver.
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Celgene's Revlimid Extends Life in Cancer Trial

(Reuters) May 5, 2011 - Celgene Corp's cancer drug, Revlimid, significantly extended the lives of patients with multiple myeloma who took the drug as a maintenance therapy following a stem cell transplant.
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Supplements Don't Prevent Prostate Cancer: Study

(Reuters) May 4, 2011 - A new study deflates hopes that certain nutritional supplements could stave off prostate cancer, the second most common cancer in men.
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Supplements Don't Prevent Prostate Cancer: Study

(Reuters) May 4, 2011 - A new study deflates hopes that certain nutritional supplements could stave off prostate cancer, the second most common cancer in men.
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Senate Bill Introduced to Correct Medicare Drug Reimbursement

(Yahoo! Finance) May 5, 2011 - U.S. Senator Pat Roberts (R-KS) and lead co-sponsor U.S. Senator Debbie Stabenow (D-MI) have introduced S. 733, a bipartisan bill designed to address a Medicare reimbursement flaw.
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Perspective: Listening to Provenge — What a Costly Cancer Treatment Says About Future Medicare Policy

(NEJM) May 5, 2011 - In April 2010, the Food and Drug Administration (FDA) approved sipuleucel-T (Provenge), a novel cellular immunotherapy for the treatment of asymptomatic or minimally symptomatic, metastatic, castration-resistant (hormone-refractory) prostate cancer.
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Swedish Study Finds Surgery For Prostate Cancer Better Than Waiting

(NPR's Health Blog) May 4, 2011 - A Swedish study suggests that radical prostatectomy — complete removal of the prostate gland — is better than "watchful waiting" for the treatment of younger men with low-risk prostate cancer.
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Novartis: We're Paying for Reform Without Seeing Benefits Yet

(CNNMoney/Fortune) May 3, 2011 - Swiss drug maker Novartis AG is facing tough competition from generics as several of its key drugs -- namely, bestseller Diovan for hypertension -- begin to lose patent protection in 2012.
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Pfizer’s Read Reviews Units With $18.3 Billion in Revenue

(Bloomberg) May 3, 2011 - Pfizer Inc. Chief Executive Officer Ian Read said he is reviewing the possible sale or spinoff of four divisions with $18.3 billion in annual revenue, led by the company’s third-biggest unit, established products.
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Novartis: New Analysis Highlights Safety Of Lucentis

(NASDAQ/Dow Jones Newswires) May 4, 2011 - Novartis AG Wednesday said a new analysis undertaken by Johns Hopkins University highlights the safety of the use of eye medicine Lucentis.
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FDA, FTC Seek To End Sales Of Unproven STD-Treatment Drugs

(Wall Street Journal) May 3, 2011 - Halting the sale of products that make unproven claims of treating or preventing sexually transmitted diseases is the goal of a joint effort by the U.S. Food and Drug Administration and Federal Trade Commission.
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FTC’s Leibowitz Says Rising Generic Drug Deals Hurt Consumers, Need Limits

(Bloomberg) May 4, 2011 - The U.S. Federal Trade Commission said drug-company deals that delayed the introduction of cheaper generic medicines rose 63 percent last year as the agency presses Congress and the courts to limit the settlements.
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Ted Forstmann Being Treated for Brain Cancer

(FOXBusiness) May 3, 2011 - Theodore J. Forstmann has been in many corporate battles over the past four decades as one of Wall Street’s premier deal makers, but now he finds himself in what may be the biggest battle of his life.
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Nine Physicians Associated with Sarah Cannon Research Institute Named to Best Doctors List

(SCRI) May 3, 2011 - Nine Tennessee physicians affiliated with the Sarah Cannon Research Institute (SCRI) were chosen by fellow physicians as Best Doctors in America for 2011-2012.
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Via Oncology Pathways Now Incorporate Advance Care Planning Decision Support

(Yahoo! Finance) May 4, 2011 - The most recent release of Via Oncology Pathways from D3 Oncology Solutions (D3) now includes decision support for advance care planning to encourage early discussions between oncologists and their patients about the disease, treatment intent and likely outcomes.
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Tool Weighs Benefits, Risks of Raloxifene or Tamoxifen to Prevent Breast Cancer

(NCI Cancer Bulletin) May 3, 2011 - Researchers have developed a benefit-risk index to help guide decisions on whether postmenopausal women at increased risk of developing breast cancer should take raloxifene or tamoxifen to reduce that risk.
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Design Dilemma: The Debate Over Using Placebos in Cancer Clinical Trials

(NCI Cancer Bulletin) May 3, 2011 - Ask a clinical researcher in almost any field except cancer for the “gold standard” of assessing the effectiveness of a new therapeutic drug and you will probably get the same answer: a randomized double-blinded placebo-controlled trial.
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2011 ASCO Annual Meeting—The Front Line in the Fight Against Cancer

(ASCO Connection Magazine) April 2011 - June 3-7, oncology professionals from across the globe will gather at McCormick Place in Chicago, Illinois, to review the latest scientific data, examine new technologies, and connect (or re-connect) with colleagues. Registration, housing, and preliminary session information are available online at chicago2011.asco.org.
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Oxford BioMedica Grants Partner Pfizer Diagnostic Rights to 5T4 Tumor Antigen

(GEN News) May 4, 2011 - Oxford BioMedica has expanded its 5T4 tumor antigen therapeutics collaboration with Pfizer by granting the latter nonexclusive rights to the diagnostic use of antibodies against the antigen and an option to commercialize a 5T4-based diagnostic.
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