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Archived News Headlines

We have been archiving all OBR daily news stories since March 2008. Use the box below to search our archives for specific articles and content.

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Updated Single Agent Phase 2 Data of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Renal Cell Carcinoma Reported at the Eighth International Kidney Cancer Symposium

(MSN Money) Sept 29, 2009 - KRX-0401 (Perifosine) continues to demonstrate impressive efficacy, safety and tolerability in metastatic renal cell carcinoma patients who progressed after failing treatment with both a VEGF receptor inhibitor and an mTOR inhibitor.
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Plexxikon Announces First Patient Dosed in First of Two Pivotal Trials of PLX4032 for Metastatic Melanoma

(Yahoo! Finance) Sept 29, 2009 - Plexxikon Inc. announces that enrollment has been initiated and the first patient has been treated in the first of two pivotal trials of PLX4032 (RG7204) in patients with metastatic melanoma.
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Onyx Starts Filling Tumor Trial

(San Francisco Business Times) Sept 28, 2009 - Onyx Pharmaceuticals Inc. started enrolling patients in a Phase I trial of a drug that could treat advanced solid tumors.
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Synta Pharmaceuticals Initiates Fourth Trial of STA-9090, a Novel Synthetic Small Molecule Hsp90 Inhibitor

(SmartBrief.com) Sept 29, 2009 - Synta Pharmaceuticals Corp., a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today announced that it has initiated a Phase 1/2 clinical study of its novel heat shock protein 90 (Hsp90) inhibitor, STA-9090 in hematologic malignancies with a once-a-week dosing schedule.
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Scientists Discover How Chemo Can Make Women Infertile

(U.S. News & World Report) Sept 28, 2009 - Italian researchers say they have identified the mechanism by which chemotherapy can rob a woman of her ability to have children.
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Roche Says Enrollment in Avastin Breast Cancer Study Halted Over Safety Concern

(The Star-Tribune) Sept 25, 2009 - Swiss drug developer Roche said Friday six cases of patients with heart failure symptoms prompted a halt to enrollment in a National Cancer Institute sponsored study of its blockbuster drug Avastin.
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Penn Studies Point To Strategies for Reducing Painful Breast Cancer Drug Side Effects

(Penn Medicine) Sept 28, 2009 - Aromatase inhibitors, the same drugs that have buoyed long-term survival rates among breast cancer patients, also carry side effects including joint pain so severe that many patients discontinue these lifesaving medicines.
read press release 



US FDA Eyes Possible Risk with Novartis Iron Drug

(Forbes.com) Sept 25, 2009 - U.S. health officials are looking into whether patients with a certain bone marrow disorder are more at risk for death and serious complications with Novartis AG's drug Exjade.
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Wyeth’s Prempro Boosted Breast-Cancer Rate, Jury Told

(Bloomberg) Sept 25, 2009 - Wyeth’s hormone-replacement therapy drug Prempro caused hundreds more women to be diagnosed with breast cancer, including an Illinois woman who had a lower risk for developing the disease, a lawyer said at the end of a trial in Philadelphia.
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Roche Says Enrollment in Avastin Breast Cancer Study Halted Over Safety Concern

(The Star-Tribune) Sept 25, 2009 - Swiss drug developer Roche said Friday six cases of patients with heart failure symptoms prompted a halt to enrollment in a National Cancer Institute sponsored study of its blockbuster drug Avastin.
read article 



US FDA Eyes Possible Risk with Novartis Iron Drug

(Forbes.com) Sept 25, 2009 - U.S. health officials are looking into whether patients with a certain bone marrow disorder are more at risk for death and serious complications with Novartis AG's drug Exjade.
read article 



Wyeth’s Prempro Boosted Breast-Cancer Rate, Jury Told

(Bloomberg) Sept 25, 2009 - Wyeth’s hormone-replacement therapy drug Prempro caused hundreds more women to be diagnosed with breast cancer, including an Illinois woman who had a lower risk for developing the disease, a lawyer said at the end of a trial in Philadelphia.
read article 



Gadget Can Diagnose Prostate Cancer in 30 Minutes

(The Toronto Star) Sept 27, 2009 - Toronto researchers have developed a portable device they say will accurately diagnose prostate cancer in 30 minutes.
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Should All Men Be Screened for Prostate Cancer?

(ABC News) Sept 25, 2009 - Screening all men for prostate cancer using a currently available common blood test is not worthwhile, according to a new study.
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M. D. Anderson Examines Use of Toad Venom in Cancer Treatment

(M. D. Anderson) Sept 24, 2009 - Phase I study shows the traditional Chinese medicine is well-tolerated.
read press release 



Pancreatic Cancer: Hard to Diagnose, Even Harder to Treat

(Los Angeles Times) Sept 28, 2009 - Though several drug trials have failed, research is continuing.
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Vitamin D May Improve Melanoma Survival

(BusinessWeek.com) Sept 27, 2009 - Higher levels of vitamin D are linked to less severe, less deadly melanoma lesions in people with skin cancer, new research suggests.
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Dendreon Starts Growing Up

(Forbes.com) Sept 25, 2009 - A clear-eyed analyst meeting marks a turning point for the drugmaker.
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NovoCure, Ltd., Announces the Closing of a Financing Round Including New Investors Pfizer Inc, Johnson & Johnson Development Corporation and Index Ventures

(CNBC.com) Sept 28, 2009 - NovoCure, Ltd., a privately held medical device company focused on developing the Novo-TTF device, a non-invasive portable medical device for the treatment of cancer, announced the completion of a new funding round today.
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Speedier Tests for Cancer Planned

(BBC News) Sept 25, 2009 - GPs in England are to get speedier access to diagnostic tests to help spot less clear-cut cancer cases, Prime Minister Gordon Brown will pledge.
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EARLY Act Congressional Event Highlights Breast Cancer Risk Assessment

(Yahoo! Finance) Sept 28, 2009 - Testing for breast cancer risk was the subject of remarks by two featured speakers at a recent congressional reception on Capitol Hill. The event generated momentum to pass the EARLY Act and raise awareness about breast cancer in young adult women.
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M. D. Anderson Scientist Wins NIH New Innovator Award

(M. D. Anderson) Sept 25, 2009 - A unique approach to understanding how cells develop resistance to drugs has won a scientist at The University of Texas M. D. Anderson Cancer Center a New Innovator Award from the National Institutes of Health.
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Keryx Expects $20 Million From Stock Offering

(CNBC.com) Sept 28, 2009 - Keryx Biopharmaceuticals Inc. said Friday it will raise $20 million in a registered direct offering of 8 million shares of common stock.
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Drug-Benefit Industry Balks At Disclosure Measure

(CNNMoney.com) Sept 25, 2009 - The pharmacy benefit management industry Friday criticized a health-care bill provision to require more disclosure from PBMs, saying the measure would raise rather than lower prescription drug costs.
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HIV Vaccine Success May Take Decade to Unravel Why It Works

(Bloomberg) Sept 28, 2009 - The surprise finding that a combination of two experimental vaccines reduced HIV infections is confounding long-held assumptions about the AIDS virus and sending scientists back to the laboratory to address mysteries that may take a decade to solve.
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