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Archived News Headlines

We have been archiving all OBR daily news stories since March 2008. Use the box below to search our archives for specific articles and content.

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The Virtues and Vices of the NCCN Guidelines

(Medscape Medical News) Mar 16, 2015 - Now in their 20th year, the National Comprehensive Cancer Network (NCCN) guidelines have greatly evolved from early efforts and continue to add new wrinkles, according to participants in a roundtable discussion at the group's annual meeting here.
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Actinium Announces New Data From Ongoing Phase 1/2 Trial of Actimab-A Demonstrating Safety and Robust Clinical Efficacy in High Risk Elderly Acute Myeloid Leukemia Patients

(Yahoo! Finance) Mar 18, 2015 - Actinium Pharmaceuticals, Inc. announced today the completion of the third cohort of the Company's ongoing multi-center Phase 1/2 Study for Actimab-A for the treatment of newly diagnosed Acute Myeloid Leukemia (AML) in elderly patients.
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Celldex Therapeutics Announces Clinical Trial Collaboration with Roche to Evaluate the Combination of Varlilumab and MPDL3280A

(Reuters) Mar 17, 2015 - Celldex Therapeutics, Inc. announced today that it has entered into a clinical trial collaboration with Roche to evaluate the safety, tolerability and preliminary efficacy of varlilumab, Celldex's CD27 targeting investigational antibody, and MPDL3280A (anti-PDL1), Roche's investigational cancer immunotherapy in a Phase 1/2 study in renal cell carcinoma.
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When Cancer Cells Stop Acting Like Cancer

(GUMC) Mar 16, 2015 - Cancer cells crowded tightly together suddenly surrender their desire to spread, and this change of heart is related to a cellular pathway that controls organ size. These two stunning observations are reported today by researchers at Georgetown Lombardi Comprehensive Cancer Center in the journal Oncogene.
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New Brain Cancer Clinical Trial Launched at CTRC

(UTHSC at San Antonio) Mar 17, 2015 - Technology, developed at the Cancer Therapy & Research Center at The University of Texas Health Science Center at San Antonio, uses tiny radioactive liposomes, or fat particles, only 100 nanometers across, inserted by the thinnest of catheters directly into a brain tumor.
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Early Recall Rates Decline After Second Round of Lung Cancer Screening

(IASLC) Mar 17, 2015 - The German Lung Cancer Screening Intervention Trial (LUSI) shows that the early repeat scan rate for suspicious findings decreased by more than 80% with the second and subsequent low-dose computed tomography (LDCT) screens, but emphasizes the need to have an organized screening program with the baseline scan available for comparison.
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NCCS Pioneers New Drug Regimen Which Reduces Toxicities for Renal Cancer Patients

(NCCS [Singapore]) Mar 18, 2015 – A study led by the Genitourinary (GU) oncology team at National Cancer Centre Singapore (NCCS) has revealed conclusive results in reducing toxicities for Asian patients with metastatic renal cell carcinoma (mRCC) or cancer that has spread beyond the kidney.
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Researchers Show How Fatty Acids Can Fight Prostate Cancer

(WSU) Mar 18, 2015 - Washington State University researchers have found a mechanism by which omega-3 fatty acids inhibit the growth and spread of prostate cancer cells. The findings, which are at odds with a 2013 study asserting that omega-3s increase the risk of prostate cancer, point the way to more effective anti-cancer drugs.
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Study Suggests Precision Medicine for Adrenal Cancer

(U-M CCC) Mar 17, 2015 - In a randomized phase 3 trial, adrenal cancer patients receiving the investigational drug linsitinib fared no better than patients receiving a placebo.
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Dietary Dioxins Don't Seem to Increase Breast Cancer Risk: Study

( News) Mar 17, 2015 - Consuming low levels of chemicals called dioxins in food doesn't increase the risk of breast cancer, contends a new study that challenges a widely held belief about the effect of dioxins.
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Tumour Determination in Bowel Cancer: Blood Test Replaces Surgery

(Medical University of Vienna) Mar 18, 2015 - A new study at the MedUni Vienna's Comprehensive Cancer Center (CCC) is assessing patients with metastasised bowel cancer to determine whether it is possible to characterise tumour and better control resistance mechanisms with a blood test.
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Sirtex Medical Slumps as Radiation Treatment Fails in Study

(Bloomberg) Mar 16, 2015 - Sirtex Medical Ltd. slumped the most on record after its radiation treatment failed to meet a primary goal in a clinical trial.
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Study: Prices of Cancer Drugs Have Soared Since 1995

(MIT News) Mar 18, 2015 - The prices of leading cancer drugs have risen at rates far outstripping inflation over the last two decades, according to a new study co-authored by an MIT economist — but the exact reasons for the cost increases are unclear.
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Soon: Survival Results for Metastatic Breast Cancer Drug

(Medscape Medical News) Mar 17, 2015 - Clinicians will soon know whether palbociclib (Ibrance, Pfizer), the newly approved treatment for metastatic breast cancer, can deliver a significant improvement in overall survival in this setting — a rare achievement.
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Nektar Drug Fails Late-stage Study in Breast Cancer Patients

(Reuters) Mar 17, 2015 - Nektar Therapeutics said its experimental drug failed to meet the main goal in previously treated patients with advanced breast cancer in a late-stage study.
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Nektar Therapeutics Reports Phase 3 BEACON Missed Primary Endpoint

(StreetInsider) Mar 17, 2015 - Nektar Therapeutics announced topline results from its Phase 3 BEACON study evaluating single-agent NKTR-102 in patients with advanced breast cancer.
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Aspirin's Colon-cancer Benefits Backfire for Some DNA Types: Study

(Reuters) Mar 17, 2015 - Although numerous studies have shown that regular use of aspirin or related drugs can reduce the risk of colorectal cancer by about 30 percent, scientists have found an important exception: The medicines can actually increase the risk in people with certain genetic variants, new research shows.
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Phase 3 Study with IMBRUVICA® (ibrutinib) Combination Demonstrates Significant Delay in Disease Progression

(Yahoo! Finance) Mar 16, 2015 - Independent Data Monitoring Committee determines HELIOS study meets its primary endpoint of progression-free survival in patients with previously treated chronic lymphocytic leukemia/small lymphocytic lymphoma at a pre-planned interim analysis.
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Valeant’s Sweetened Bid for Salix May Have Delivered 2 Knockouts

(New York Times/Dealbook) Mar 16, 2015 - By coming up with an extra 9 percent over its previous offer, the acquisitive drug maker, now backed by the hedge fund executive William A. Ackman, quickly put an end to a rival bid from Endo International.
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MD Anderson Study Predicts New Hepatitis C Drugs Will Place a Dramatic Financial Strain on the Health Care System

(MD Anderson) Mar 16, 2015 - The findings, reported in the March 17 issue of the Annals of Internal Medicine, predict that the cost of providing patients their daily regimens could total $136 billion over five years – 10 percent of the country’s annual prescription drug spending.
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House Near a Fix for Medicare Payments

(Wall Street Journal) Mar 16, 2015 - House leaders are closing in on a $200 billion package to permanently fix a flawed formula for calculating Medicare reimbursements to doctors and other health-care providers, but the emerging deal has come under fire from lawmakers in both parties.
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Novartis Pays $12.6M Fine for Giving Inaccurate Pricing Data to Medicare

(Wall Street Journal/Pharmalot blog) Mar 16, 2015 - In what the federal government says is the largest such settlement ever reached, Sandoz has agreed to pay $12.64 million to resolve allegations that it misrepresented pricing data on medicines that were provided to the Centers for Medicare & Medicaid Services.
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UCLA Study Reveals Treatment for Women with Breast Cancer Suffering Cognitive Difficulties

(UCLA) Mar 16, 2015 - Mental training exercises developed at the Jonsson Comprehensive Cancer Center have been shown to help mitigate the effects of “chemo brain”.
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Obese Women 40 Percent More Likely to Get Cancer

(Cancer Research UK) Mar 17, 2015 - Obese women have around a 40 per cent greater risk of developing a weight-related cancer in their lifetime than women of a healthy weight, according to new figures* released by Cancer Research UK today (Tuesday).
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Unique Procedure Offered for Patients with Inoperable Bile Duct Cancers

(UC) Mar 16, 2015 - University of Cincinnati Cancer Institute transplant surgeons are offering a unique procedure to remove inoperable, cancerous tumors from the bile duct of the liver, known as cholangiocarcinoma, potentially improving survival rates for patients who may otherwise have few treatment options.
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