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Phase III Trial of Anticancer Agent Lenvima As First-Line Treatment For Unresectable Hepatocellular Carcinoma Meets Primary Endpoint

(Eisai) Jan 25, 2017 - Eisai Co., Ltd. announced today that a Phase III clinical trial (Study 304) of its in-house discovered and developed anticancer agent Lenvima® (lenvatinib mesylate, “lenvatinib”) against the comparator sorafenib as a first-line treatment for patients with unresectable hepatocellular carcinoma has achieved its primary endpoint.

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Dean Gesme, MD (Posted: January 25, 2017)

quotesA very welcome advance in HCC therapy with lenvatinib dosing which is lower than the initial recommended dosing for radioiodine-resistant well differentiated thyroid cancers. Much greater expense may be an important issue compared to sorafenib. Also the second line role of regorafenib may need some further consideration versus using sorafenib in the second line.quotes

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