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Some Cancer Patients 'Hyperprogress' on Immunotherapy

(Medscape Medical News) Mar 9, 2017 - Although many people respond well to immunotherapy, some patients have cancers that appear to rapidly progress with treatment. Genomics could be the key to identifying these cases in advance.

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H. Jack West, MD (Posted: March 10, 2017)

quotesWe still have more questions than answers about the potential for patients to "hyperprogress" after exposure to immunotherapies, but this has been reported elsewhere (Champiat, Clinical Cancer Res, 2016), and several clinical groups have reported that they have anecdotally noted this phenomenon at their centers, some even noting that they are working on preparing manuscripts that characterize it more fully. This concept will be critical to understand better, especially as immunotherapy moves earlier into and more broadly across treatment paradigms in many cancers.quotes

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