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USC Study Shows Role Of Enzyme In Prostate Cancer Growth

(USC News) July 27, 2018 - A new USC School of Pharmacy study led by University Professor Jean Chen Shih offers new evidence that the monoamine oxidase-A enzyme (MAO-A) pathway could be an important target in treating prostate cancer.

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Tomasz M. Beer, MD, FACP (Posted: July 31, 2018)

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MAO-A was previously shown to be elevated in higher grade prostate cancer and our group previously reported that chemotherapy treatment resulted in elevated MAO-A levels and that MAO-A in turn modulated chemotherapy resistance (PLoS One 2014). The exciting feature is that there are drugs that are available off the shelf that can inhibit MAO-A. The concept needs to be tested.

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Tomasz M. Beer, MD, FACP

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