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Combination Therapy of Prostatectomy Plus Radiotherapy May Improve Survival in Patients with Locally Advanced Prostate Cancer

(Jefferson Health) Sept 25, 2018 - A comparison of two of the most common combination therapies for locally advanced prostate cancer show the more aggressive option is linked with a higher rate of survival.

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Tomasz M. Beer, MD, FACP (Posted: September 28, 2018)

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Optimal local therapy for high risk prostate cancer is not known. While this study suggest that surgery + radiation may yield improved outcomes over radiation (+hormonal therapy), population based analyses cannot provide high quality practice defining evidence. Treatment decisions were not made at random and likely incorporated a myriad of patient and tumor factors that patients and physicians consider when choosing therapy. The apparent difference is just as likely to reflect systematic patient selection bias as it is differences in the efficacy between two treatment approaches.

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Tomasz M. Beer, MD, FACP

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