Issue – OBR

April 2019:

Table of contents

Denial Rates and Days to Pay for Cancer Drugs: Commercial Health Plan Report Card

Reducing and Monitoring Chemotherapy Toxicities: A Fundamental Pillar to Improving Quality and Reducing Costs in Cancer Care

Targeted Therapy, Vaccines, CAR-T, and a Practice Changer at AACR 2019

March 2019:

Table of contents

As Physician Burnout Becomes Endemic, Change is in the Wind

Forecasting Interview: Michael Seiden, MD, PhD, President, The US Oncology Network

Rare Cancers Are No Longer Orphans

Forecasting Interview: Mark Awad, MD, PhD, Clinical Director, The Lowe Center for Thoracic Oncology, Dana-Farber Medical Center

Forecasting Interview: Lisa Lacasse, President, American Cancer Society Cancer Action Network (ACS CAN)

February 2019:

Table of contents

Molecular Testing Becoming Essential in AML Treatment

Pembro Shines, Chemo Earns Praise, and a Vaccine Stumbles, All at #GI19

January 2019:

Table of contents

Hematologists Use Social Media to Up their Game

A Race Well Underway: CAR-Ts Overtake ASH

The CAR-T First-Mover Advantage: Reality or Myth?

November 2018:

Table of contents

Telemedicine Enabling Oncology Care for Rural Patients

Telehealth: Improving Cancer Care Delivery

Trials Presented at ESMO 2018 Considered Practice Changing

October 2018:

Table of contents

Total Cost of Care: Site-of-Care Shift and 340B Drive Total Cost

Data-Sharing Advances the Continuum in Precision Medicine

September 2018:

Table of contents

MIPS Creates a Stir in the Real World

Overcoming Obstacles in Delivering Precision Oncology

July 2018:

Table of contents

Fireworks and Fizzle: ASCO 2018

Capturing the Elusive Patient Experience with PROs

June 2018:

Table of contents

Tumor-Agnostic Trials: When The Patient, Not the Tumor, is the Target

Game-Changing Late-Breaking Plenary Sessions at ASCO 2018

‘The Smartest Doctor’: Real-World Data Drive Decision Support Pilot Study

CAR T-Cell Therapies: Early Insights into Access and Affordability

May 2018:

Table of contents

What’s Trending in 340B

AACR 2018 Roundup: The Practice-Changing, and the Potentials

Discussing Next Generation Value-based Payment Designs

The Total Cost of Cancer Care Challenge

PBMs: What You Need to Know

April 2018:

Table of contents

A Powerful Force: Novel Endpoints Speed Up Drug Development

Digital Patient Engagement in a New Era of MACRA and Value-Based Care

March 2018:

Table of contents

Bugs R Us: How a Community of Microbes is Helping to Combat Cancer

Demographic Studies Shed Light on Risks, Prevalence of Major Cancer Types

February 2018:

Table of contents

Precision Oncology: What Recent Advancements Mean for the Industry

2018 Forecast Series: Michael Caligiuri, MD, President of the American Association for Cancer Research (AACR) 2017-2018

2018 Forecast Series: Louis J. DeGennaro, PhD, President and Chief Executive Officer, The Leukemia & Lymphoma Society

2018 Forecast Series: Frederick Locke, MD, Vice Chair of the Department of Blood and Marrow Transplant and Cellular Immunotherapy, Moffitt Cancer Center

2018 Forecast Series: Barbara McAneny, MD, CEO of New Mexico Oncology Hematology Consultants

January 2018:

Table of contents

An Enhanced Understanding of Immunotherapy in Breast Cancer Emerges

CAR-Ts on the Move: Hematologic Immunotherapy at ASH 2017

CAR and Driver: Prepping Moffitt Cancer Center to Deliver CAR-Ts

Major Trials Create New Standards of Care in Hematologic Malignancies

November 2017:

Table of contents

Experts Strategize Next-Generation Multidisciplinary Cancer Care

340B: Good Idea Gone Rogue, Reform Prevails

Cost Disparities in Site of Cancer Care Persist

October 2017:

Table of contents

The Need for Transparency with DIR Fees

How Providers and Bio-Pharma Manufacturers Can Partner to Improve Outcomes and Lower Costs

ESMO Trials Credited with Changing Standards of Care

September 2017:

Table of contents

Value Discussion in Cancer Care Continues

Hurricane Irma Hits: Largest Oncology Provider in Florida Continues to Treat Cancer Patients

Biosimilars Poised to Save Billions in Cancer Treatment

July 2017:

Table of contents

Latest in Cost and Value Discussion at ASCO '17

ODAC Recommends First Potential Gene Therapy and Two Biosimilars

June 2017:

Table of contents

Highlights from 2017 ASCO: The Practice Changing, and the Promising

Patient-Reported Outcomes (PRO) Improve the Lives of People with Cancer

2017 ASCO: It’s Back to “Precision Medicine”

May 2017:

Table of contents

Cancer Care Costs Pose a Huge Financial Burden on Patients

Hypothetical OCM. 2.0 Addresses Obstacles and Opportunities

Q&A with Ben Jones, VP, Govt Relations & Public Policy, McKesson Specialty Health

Oncology Care Model: Early Learnings

April 2017:

Table of contents

State of Cancer Care: Opportunities and Challenges

AACR 2017 Roundup: Bugs, Drugs, and an Electric Hat

Market Forces, Value-Based Frameworks, and Drug Pricing

March 2017:

Table of contents

Cancer Patients Face Uncertainty with ACA’s Repeal/Replace

Using Real-World Evidence in the Cancer Care Continuum

February 2017:

Table of contents

CAR T-Cell Therapy on Fast Track for Commercialization in 2017

Can Social Media Improve Patient Participation in Cancer Clinical Trials?

January 2017:

Table of contents

Phase 3 Hits and Misses of 2016

2017 Forecast Series—Laurie Glimcher, MD, President and CEO, Dana-Farber Cancer Institute, Discusses the Cancer “Moonshot” Initiative

2017 Forecast Series—Steve Miller, MD, Senior Vice President, Chief Medical Officer, Express Scripts, Talks About Oncology Drug Spending and Value

2017 Forecast Series—Barry Russo, Chief Executive Officer, The Center for Blood and Cancer Disorders Discusses OCM and MIPS in 2017

2017 Forecast Series—Amy McKee, MD, Acting Deputy Director, CDER's Office of Hematology and Oncology Products, Comments on the FDA Oncology Center of Excellence

November 2016:

Table of contents

Is Your Practice Ready to Maximize the OCM Performance Payment?

The Evolving Influence of Integrated Delivery Networks (IDNs) in Oncology

CVS Policy Reversal Offers Temporary Relief for Dispensing Practices

October 2016:

Table of contents

Practice-Changing Potential for Breast Cancer

Biosimilars: A Brave New World but Uncertain Terrain

At ESMO: One Anti-PD1 Agent Moves to the Head of the Line in Advanced NSCLC

Op-Ed: Our View on Value Frameworks in Oncology: Proposing Principles for Value Framework Development

September 2016:

Table of contents

The Next Wave of Immunotherapies: Costimulators

EHA 2016: Stopping TKIs in CML and Improving Overall Survival in ALL

Study Finds Cancer Costs Dont Outpace Other Health Care

July 2016:

Table of contents

Memorable Moments: The ASCO 2016 Experience for Physicians

ASCO Roundup: Biosimilars, Precision Medicine, and New Inroads

Biomarkers for Immunotherapy: Research at ASCO and Treatment Implication

Monoclonal Antibodies in Multiple Myeloma Offer Survival Hope

June 2016:

Table of contents

PD-L1 Biomarker Status: To Test or Not to Test?

Value Tools at ASCO 2016: Building a Framework for Prime Time

May 2016:

Table of contents

Getting Ready for Chicago: A Behind the Scenes Look at Designing the Annual Meeting

AACR Round Up: Immunotherapy, Breast Cancer, and Beyond

What’s in Store for ASCO 2016? Kantar Health Offers a Preview

April 2016:

Table of contents

The Uphill Climb of Precision Medicine

Why Histology Matters in Lung Cancer Treatment: Updates from the Annual Winter Lung Cancer Conference

March 2016:

Table of contents

Better Care, Better Payment, and Savings: A Win-Win-Win Approach to Payment Reform

Using Patient-Reported Outcomes (PRO) to Improve the Quality of Cancer Care

February 2016:

Table of contents

At ASH: Novel Targeted Therapies for Tough-to-Treat Blood Cancers

Hope and Hype: Questions Surround Liquid Biopsies

January 2016:

Table of contents

2016 Forecast Series - Perspective on Precision Medicine with Jennifer Carter, MD, MPH, Founder and Chief Medical Officer, N-of-One

2016 Forecast Series - Assessing Value and Clinical Benefit with Lowell E. Schnipper, MD

2016 Forecast Series - On Curing Cancer with Vincent T DeVita Jr MD

2016 Forecast Series - The Future of Immuno-Oncology with Patrick Ott, MD, MPH

Phase 3 Hits and Misses of 2015

Discussing Value in Hematology: An On-Conversation with ZS Associates

December 2015:

Table of contents

Extending and Enhancing Patient Care Beyond the Office with Patient Portals

The Evolving Role of PD-L1 Testing in Immunotherapy of Metastatic Melanoma and Non-Small Cell Lung Cancer

November 2015:

Table of contents

Oncologists Become More Vocal About Rising Costs

Evidence Development and Payer Risk: Planning the Route to Market Access

IB/MAB Worksheet

October 2015:

Table of contents

Oncotype DX® Colon Cancer Assay for Stage II Colon Cancer Integrates Colorectal Surgeons into Multidisciplinary Care

ACCC-ICLIO: Navigating the Future of Immuno-Oncology and Who’s Going to Pay for It

New Tools from NCCN and ASCO Address Value

Five Hits and a Dud: A Snapshot of the 2015 European Cancer Congress

September 2015:

Table of contents

Innovations in Precision Medicine Introduced at ASCO 2015

The Ubiquity of Immunotherapy: Whats Next?

Beyond the Peak: Four Levers to Address Quickly Plateauing Oncology Drug Sales

July 2015:

Table of contents

European Hematology Association: Remains of the Day

The Impact of BRCA Testing: Research at ASCO and Treatment Implications for Ovarian, Breast, Prostate, and Pancreatic Cancers

June 2015:

Table of contents

Cancer Immunotherapy at ASCO: Bringing Down the House

Targeted Therapies for Hematologic Malignancies Attract Attention at ASCO 2015

What Are Payers Pondering about the New Wonder Drugs?

Emerging Role for Biomarkers and Implications for Care

Value As A Decision Driver In Cancer Care: Are We There Yet?

Immunotherapies Take Center Stage at ASCO 2015

May 2015:

Table of contents

What’s in Store at ASCO 2015? Kantar Health Offers a Preview

AACR 2015: Immunotherapy Marches On

April 2015:

Table of contents

Integrated Delivery Networks and Oncology Care Delivery: Changing the Tide, or Changing the Sign Outside?

PBS “Emperor” Broadcast Stokes a Discussion on Cancer Research’s Future

SUCCESS! Repeal of the Sustainable Growth Rate Formula

March 2015:

Table of contents

ASCO, Payers, and COA React to CMMI’s New Oncology Care Model

Value-Based Decision-Making at the Bedside

February 2015:

Table of contents

5th Annual Outlook on the Biopharmaceutical Promotional Landscape in Oncology: Evolving Sales Models and Promotional Effectiveness

CAR-T Cell Therapies Moving Toward Clinic

January 2015:

Table of contents

2015 Forecast Series—Otis Brawley, MD, FACP, Chief Medical Officer, American Cancer Society (ACS)

2015 Forecast Series—ASCO Priorities and Objectives with Peter Paul Yu, MD, ASCO President

2015 Forecast Series—Bruce Gould, MD, Northwest Georgia Oncology Centers, President of Community Oncology Alliance (COA)

Phase 3 Hits and Misses for 2014

November 2014:

Table of contents

Market Conditions that Impact New Oncology Product Uptake

Patient Affordability: The Most Important Non-Clinical Attribute in Choosing Between Treatment Options

Experts Tackle Gaps in Cancer Care and Best Use of Interventions

October 2014:

Table of contents

Five Strategic Considerations for Biosimilar Commercialization

Clinical Pathways Can Lead to Cost Savings, Better Care

ESMO Redux: All-Stars and Also-Rans

Key Features of the CMMI Oncology Care Model (OCM)

September 2014:

Table of contents

Evolution of Angiogenesis Biomarkers: What the Future Holds

Oncotype DX® Colon Cancer Assay Improves Recurrence Risk Stratification in Stage II Colon Cancer Patients

The Shifting Sands of the Prostate Cancer Treatment Landscape

The Catalysts are Coming! The Catalysts are Coming!

July 2014:

Table of contents

The Complexities of Immunotherapies: CARs, TILs, and TCRs

Beyond KRAS exon 2: Research at ASCO and Important Treatment Implications for Metastatic Colorectal Cancer

Novel Therapies for Leukemia Attract Attention at ASCO 2014

June 2014:

Table of contents

The Three “A’s” of Treatment Options: Approved, Accessible and Affordable - Market Access Implications of Big News from ASCO 2014

Targeted Therapies Stay in the Spotlight: Late Breaking Studies in NSCLC, Thyroid, and Ovarian Cancers

Immunotherapies at ASCO 2014: Checkpoint Inhibitors

Hits And Misses at ASCO 2014

May 2014:

Table of contents

Newfound Risk that Providers, Payers, and Patients Are Navigating with the Implementation of the Affordable Care Act

What’s in Store at ASCO 2014? Kantar Health Offers a Preview

Can Innate Immune Cells Engage in Anti-Tumor Activity?

In Anticipation of ASCO: What’s Next for Cancer Immunotherapy…? Combinations of Course!

April 2014:

Table of contents

UnitedHealthcare: Measuring Quality Outcomes in Oncology

A Revolution in Cancer Care: Cancer Immunotherapeutics in the Pipeline

Spearheading a PSA and Co-Management Agreement Between a Practice and a Hospital: Making it Work!

March 2014:

Table of contents

The Evolving Use of White Bagging in Oncology

ASCO Reports on the State of Cancer Care in America in 2014

New Clinical Trials Designed to Better Leverage Precision Medicine

February 2014:

Table of contents

Peter B Bach Discusses New Payment Reform Models Challenging Fee For Service

Antibody Drug Conjugates and Nanotechnology Driving New Advances in Personalized Cancer Therapeutics Development

January 2014:

Table of contents

2014 Forecast Series-A conversation with Nancy Davenport-Ennis

2014 Forecast Series-Looking ahead with Matthew Farber, MA

2014 Forecast Series-Insights from Neal Meropol, MD

2014 Forecast Series-ASCO priorities and objectives with Allen S. Lichter, MD

Phase 3 Hits & Misses of 2013

Three Industry Developments in Precision Medicine in 2013 Set the Stage for Broader Availability

December 2013:

Table of contents

Lessons Learned from the First FDA-Approved Breakthrough Therapies

Health Information Exchanges: Some Community Practices Are Benefitting, Many Are Not

Innovative Cancer Care and the Initiation of the COME HOME Medical Home Program

November 2013:

Table of contents

Are GPOs Helping Community Oncology Survive?

Pancreatic Cancer May No Longer Be Immune to Therapy as Pipeline Agents Make Progress

The Evolving Landscape of Payment Care Delivery and Manufacturer Implications of Coverage Expansion

October 2013:

Table of contents

IB/MAB Worksheet

Innovation in EHR Technology Drives Quality Oncology Care and Offers Solutions to the Challenges Facing Community Oncologists

Developing a Biosimilar Defense Strategy

September 2013:

Table of contents

FDA’s New Breakthrough Therapy Designation: What does it mean for Pricing and Market Access?

Challenges with Adherence Highlight Unmet Needs in Oncology

Cost Challenges in Developing New Oncology Drugs

July 2013:

Table of contents

An OBR Survey: Ownership and Usage of Oncology Treatment and Diagnosis Data

Breast and Lung Cancer Biomarker Research at ASCO: Changing Treatment Patterns

June 2013:

Table of contents

Companion Diagnostics Are Driving Support in the Evolving Regulatory Landscape

CancerLinQ Proof-of-Principle Demonstrated at 2013 ASCO Annual Meeting

“Bridges Built” at the 2013 ASCO Annual Meeting

Advances in Metastatic Melanoma Bring Price Competition, Redefinition of Value, and Likely Increased Payer Utilization Management

May 2013:

Table of contents

Outlook for Patient Support Philanthropies

ASCO 2013 Is Almost Here! Kantar Health Previews the Top Abstracts

Oncology Practice Leaders Refocusing Efforts to Improve Long Term Viability

March 2013:

Table of contents

Molecular Testing: Preparing for the New Normal in Community Oncology

Community Counts: A Discussion With ION Senior Vice President Barry Fortner, PhD, Regarding a New Initiative to Help Community Oncologists

Success Factors for Building an Oncology Business (Part One)

February 2013:

Table of contents

Tackling Rising Oncology Healthcare Costs: Aetna and The West Clinic Provide Solutions

Transitioning to Value Based Oncology: Strategies to Survive and Thrive

The Evolving Dynamics of Specialty Pharmacy in Oncology

January 2013:

Table of contents

AACR President Frank McCormick PhD Reflects on Past Progress and Looks to the Future

Forecasting 2013: A Look Forward at Issues Affecting Oncology

Anatomy of a Deal: University of Virginia Health System Acquires Hematology Oncology Patient Enterprise

November 2012:

Table of contents

Recent Surge in FDA Approvals Shakes up the Oncology Promotional Landscape

Pilot Phase of Michigan Oncology Medical Home Demonstration Project Launches: Patient Satisfaction Increases, Future Phases Planned

October 2012:

Table of contents

Patient-Reported Outcomes Provide New Insights into Breast Cancer Survivors

The Business Case for Integrating Palliative Care into Oncology Practice

Can Practices Successfully Dispense Oral Anti-Cancer Agents In-House?

September 2012:

Table of contents

Oncology Practices Be Prepared! Meaningful Use Stage 2 Is Here! Well Almost

The Promise of Oral Anticancer Agents: Addressing Compliance and Affordability

The Rapidly Evolving ACO World

Are Medical Homes and ACOs the Future of Cancer Care

July 2012:

Table of contents

Ensuring a Compelling Value Proposition in Oncology

ASCO President Michael P. Link, MD, Addresses the 2012 Annual Meeting

The Promising Outlook With Immunoconjugate Therapy

PD-1 Immunotherapy Makes a Splash at ASCO

Most Popular News Stories in OBR vs Most Popular in the Media

On-Conversation with Michael Tardugno, President, CEO, Celsion Corporation

Spotlight on Cost of Cancer Care: Trastuzumab

Most Cancer Patients Will Be Treated in Integrated Delivery Networks (IDN) and Cancer Institutions by 2016, Predicts New Report

May 2012:

Table of contents

The Rise of Companion Diagnostics: A Step Towards Truly Personalized Medicine

Kantar Health’s Top Picks: What’s Hot at ASCO 2012

Peter B. Bach, MD, and the Case for Interchangeability in Oncology: A New Model for an Episode-based Payment System

Achieving Accountable Cancer Care

On-Conversation with Michael N. Neuss, MD, Chief Medical Officer of the Vanderbilt-Ingram Cancer Center

Diagnostic Testing and Clinical Pathways Move into the PA Neighborhood

Spotlight on Cost of Cancer Care: Panitumumab

March 2012:

Table of contents

Solid Tumor Agents Dominate the Future of Biomarkers

After an Eventful 2011, What’s in the Pipeline for Emerging Technologies in Oncology?

Spotlight on Cost of Cancer Care: Rituximab

The Use of Hsp90 Inhibitors in the Treatment of Lung Cancer

Digital Patient Engagement: Next Steps in the Provider-Patient Relationship

January 2012:

Table of contents

New Frontiers and Novel Mechanism of Action in Hematologic Malignancies

Shining a Light: How the Sunshine Provision May Impact Promotion

Consumerism in Oncology: How Will it Affect Cancer Care?

The OBR Top 10 Oncology Stories of 2011

The 4th Annual Outlook on the Pharmaceutical Promotional Landscape Within Oncology

September 2017 Edition Vol.11, Issue 9

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