Our free daily oncology focused e-news service.

Featured Oncology News

Trump Administration Postpones Some Medicare Drug-Cost Proposals

(CNBC) May 17, 2019 - The Trump administration has decided to put part of its Medicare drug cost-cutting proposals on hold, for now. The administration says it will not give health plans the authority to negotiate pricing for certain drugs considered protected classes.

read article

CMS Statement: Delay in Final Chimeric Antigen Receptor (CAR) T-cell therapy National Coverage Determination

(CMS.gov) May 17, 2019 - From a CMS spokesperson: “CMS will not be issuing a final National Coverage Determination on CAR T-cell therapy for cancer today, but a decision is forthcoming.” To read the proposed decision, visit the CMS website at: https://www.cms.gov/medicare-coverage-database/details/nca-tracking-sheet.aspx?NCAId=291

read press release

AbbVie Provides Update on Depatuxizumab Mafodotin (Depatux-M), an Investigational Medicine for Newly Diagnosed Glioblastoma, an Aggressive Form of Brain Cancer

(AbbVie) May 17, 2019 - Phase 3 INTELLANCE-1 study, conducted in collaboration with the RTOG Foundation, did not meet primary endpoint of overall survival at the interim analysis and demonstrated no survival benefit for patients receiving Depatux-M. Independent Data Monitoring Committee responsible for interim analysis data review recommended stopping the study due to lack of survival benefit. Enrollment in all ongoing Depatux-M studies has been halted.

read corporate press release

Oncology Clinical News

MacroGenics Thrives Following Positive Breast Cancer Results

(BioSpace) May 16, 2019 - The trial evaluated margetuximab in patients with HER2-positive metastastic breast cancer who had already been treated with anti-HER2-targeted therapies.

read article

Blood Test Can Measure Effectiveness of Treatments for Aggressive Skin Cancers

(NYU Langone Health) May 16, 2019 - Blood tests that track the amount of tumor DNA can—after only one month of drug therapy—detect how well treatment is working in patients with skin cancer, a new study finds.

read press release

A New Way Of Diagnosing And Treating Disease—Without Cutting Skin

(UBC Vancouver) May 15, 2019 - UBC researchers develop new laser microscope that could be ‘revolutionary’ for treatment of diseases such as skin cancer.

read article

Broccoli And Brussels Sprouts: Cancer Foes

(Harvard Gazette) May 16, 2019 - Research finds compound in such cruciferous vegetables that may help to suppress tumors.

read article

Bristol-Myers Squibb to Present New Data on 20 Types of Cancer from Across its Oncology Portfolio at ASCO and EHA 2019

(BMS) May 16, 2019 - New data on Opdivo (nivolumab) plus Yervoy (ipilimumab) in patients with advanced hepatocellular carcinoma and in melanoma patients with symptomatic brain metastases. New long-term survival data and health outcomes research on Opdivo in combination with Yervoy in advanced melanoma.

read corporate press release

Takeda to Showcase Growing Pipeline and Diversified Portfolio of Oncology Products at Upcoming Scientific Congresses

(Yahoo! Finance) May 16, 2019 - New data to be presented at the American Society of Clinical Oncology (ASCO) Annual Meeting and the Congress of the European Hematology Association (EHA) demonstrate advancements in medicines designed to address the unmet needs of patients for a variety of cancers.

read article

Incyte Announces Abstracts Accepted for Presentation at the 2019 ASCO Annual Meeting and the 24th Congress of EHA

(AFP) May 16, 2019 - Abstracts accepted for presentation at ASCO feature genomic profiling data from Incyte’s ongoing Phase 2 FIGHT-202 trial evaluating its selective fibroblast growth factor receptor (FGFR) inhibitor, pemigatinib, in patients with cholangiocarcinoma, as well as efficacy and safety data from the Novartis-sponsored GEOMETRY mono-1 trial of capmatinib, the investigational selective MET inhibitor licensed to Novartis by Incyte.

read article

Nektar Therapeutics Announces Five Accepted Abstracts at 2019 American Society of Clinical Oncology's (ASCO) Annual Meeting

(Nektar) May 15, 2019 - Nektar Therapeutics today announced five abstracts accepted for presentation at the 55th Annual Meeting of the American Society of Clinical Oncology (ASCO), which is being held from May 31 to June 4, 2019 at the McCormick Place Convention Center in Chicago, Illinois.

read corporate press release

Jazz Pharmaceuticals to Present New Data at Upcoming ASCO Annual Meeting and EHA Congress

(Yahoo! Finance) May 16, 2019 - Jazz Pharmaceuticals plc announced today that it will present data from across its hematology/oncology portfolio and pipeline at the upcoming American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago from May 31-June 4, 2019 and at the 24th Congress of the European Hematology Association (EHA) in Amsterdam from June 13-16, 2019.

read article

Epizyme Announces New Tazemetostat Clinical Data to be Presented in Oral Sessions at Multiple Upcoming Medical Meetings

(MarketWatch) May 16, 2019 - Epizyme, Inc. today announced that new data from the epithelioid sarcoma and follicular lymphoma cohorts of the company’s ongoing Phase 2 clinical trials of tazemetostat will be reported during oral presentations at medical meetings in June.

read article

Oncology Business and Policy News

Needless Government Meddling Is Making An Amazing New Cancer Treatment Harder To Get

(The Federalist) May 17, 2019 - Chimeric Antigen Receptor (CAR) T-cell therapy might be the cancer cure patients have been waiting for—if only the government would get out of the way.

read article

HHS Hears Cancer Patients’ Concerns About Timely Access to Drug Therapies in Medicare Part D

(ACS CAN) May 16, 2019 - Today the Department of Health and Human Services (HHS) issued its final rule for Medicare Part D which does not include the full range of proposed changes to drugs in the ‘six protected classes’ of cancer, epilepsy, HIV/AIDS, mental illness and organ transplants.

read press release

FDA to Launch Expanded Access Pilot ‘Project Facilitate’ by End of May

(Regulatory Focus) May 16, 2019 - Ahead of the launch of a new pilot aimed at improving patient access to unapproved oncology drugs, dubbed Project Facilitate, the US Food and Drug Administration (FDA) held a public workshop on Thursday explaining its goals for the initiative and to discuss ongoing issues related to expanded access. According to Richard Pazdur, director of FDA’s Oncology Center of Excellence, the pilot will be rolled out towards the end of May. “Access to clinical trials and access to novel therapeutics for patients is still a problem. We know that not all oncologists or healthcare providers have the regulatory expertise or resources to navigate the single patient [investigational new drug] IND process, and I know many oncologists just assume the process is cumbersome without even trying it,” said Acting FDA Commissioner Ned Sharpless.

read article

ASCO Abstracts: Breast Cancer, Precision Treatments in the Spotlight

(Xconomy National) May 16, 2019 - The world’s biggest annual cancer conference is just around the corner.

read article

Here's Why Mirati Therapeutics Is Surging Today

(Yahoo! Finance/The Motley Fool) May 16, 2019 - Shares of Mirati Therapeutics, a clinical-stage biotechnology company developing new cancer drugs, are on the move thanks to enthusiasm for its experimental KRAS inhibitor.

read article

Revlimid, Imnovid Combos Receive EU Approval

(PharmaTimes [UK]) May 17, 2019 - The European Commission has approved two of Celgene’s combination regimens involving Revlimid (lenalidomide) and Imnovid (pomalidomide).

read article

NICE Recommends Revlimid As Multiple Myeloma Alternative

(PharmaTimes [UK]) May 17, 2019 - The National Institute of Health and Care Excellence (NICE) has recommended Revlimid (lenalidomide), a drug that helps to support the immune system to fight blood cancer.

read article

QIAGEN and Inovio Collaborate to Develop Companion Diagnostic for Novel Immunotherapy Targeting Precancerous Cervical Lesions

(AP) May 16, 2019 - Liquid biopsy-based Precision Medicine test to guide patient selection for Inovio’s VGX-3100.

read article

New York’s First Proton Therapy Center to Open in July

(Wall Street Journal) May 16, 2019 - Many oncologists say that proton therapy can be more effective than standard radiation that uses photons, which is less precise and can cause damage to normal tissue.

read article (paid subscription required)

Apps Are Promising To Match Cancer Patients To Clinical Trials. An Ethicist Digs Into What Could Go Wrong

(STAT Plus) May 17, 2019 - If you talk to cancer researchers about barriers to scientific progress, you’ll probably hear this statistic: Only about 8% of people with cancer actually take part in clinical trials.

read article (paid subscription required)

Case Comprehensive Cancer Center Awarded $8.9 Million To Expand Access To Clinical Trials

(Crain’s Cleveland Business) May 16, 2019 - Case Comprehensive Cancer Center has been awarded an $8.9 million grant that will enable the center to provide patients additional access to clinical trials through the National Clinical Trials Network.

read article

Former 21st Century Oncology Docs Suing Over Contracts Win Florida Lawmakers' Backing

(Fort Myers News-Press) May 13, 2019 - A group of cancer doctors suing 21st Century Oncology in federal court to get out of their non-compete contracts may have found a quicker route to win their legal battle: the Florida Legislature.

read article

Editorial: Texas' Investment In Cancer Research Is Paying Off, But Is Its Funding Sustainable?

(Dallas Morning News) May 15, 2019 - CPRIT is the reason 170 cancer researchers and their labs are in the state, including James Allison at the University of Texas MD Anderson Cancer Center, who won the 2018 Nobel Prize from an innovative approach to cancer therapy.

read article

Broader Healthcare and Pharma News

Gilead CEO Insists Federal Government Patent For HIV Prevention Pill Truvada Is Invalid

(Washington Post) May 16, 2019 - The chief executive of Gilead Sciences, the nation’s leading manufacturer of HIV drugs, defended the high cost of a key drug that prevents the lethal infection, telling a House committee Thursday that its hefty profits pay for continued research.

read article (free registration required)

House Passes Legislation Aiming to Shore Up Health Law and Lower Drug Costs

(New York Times) May 16, 2019 - The House on Thursday passed a suite of health care bills that tied shoring up the Affordable Care Act to lowering drug prices, as Democrats tried to hold Republicans to their campaign promises to secure coverage for pre-existing medical conditions and rein in the cost of prescription medicine.

read article

5 States Announce New Suits Over Prescription Opioids

(AP) May 16, 2019 - Five more state attorneys general announced legal filings Thursday seeking to hold the company that makes OxyContin responsible for an opioid addiction crisis that’s now the leading cause of accidental deaths across the country and in many states.

read article

MN Lawmakers Move To Regulate Pharmacy Benefit Managers. Will That Bring Drug Costs Down?

(Pioneer Press) May 16, 2019 - With just four days left in the legislative session, Minnesota lawmakers struck an agreement to license and regulate pharmacy benefit managers.

read article