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FDA Grants Priority Review For Amgen's BLINCYTO® (blinatumomab) Supplemental Biologics License Application

(Yahoo! Finance) Mar 29, 2017 - Amgen today announced that the U.S. Food and Drug Administration (FDA) has accepted for priority review the supplemental Biologics License Application (sBLA) for BLINCYTO® (blinatumomab) to include overall survival (OS) data from the Phase 3 TOWER study.

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Novartis Makes Plans For Its Cancer-Killing T Cells

(Forbes) Mar 29, 2017 - There's a race on to be the first company to launch what's a CAR-T -- a technology that genetically alters cancer patients' white blood cells to kill tumor cells. (It stands for chimeric antigen receptor T-cell, which means "white blood cells with genetically altered receptors.")

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Oncology Clinical News

Keyhole Surgery a ‘Better Approach’ For Women With Early Stage Womb Cancer

(Cancer Research UK/Press Association) Mar 29, 2017 - Survival in women who have less invasive surgery for early-stage womb cancer is just as good as traditional surgery, an Australian study has found.

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HPV Vaccine Could Protect More People With Fewer Doses, Doctors Insist

(NPR/Shots blog) Mar 29, 2017 - In the U.S., there are about 39,000 cancers associated with the human papillomavirus each year. Doctors say the new HPV vaccine may help reduce the number of cases.

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Got the HPV Vaccine Before You Knew You Were Pregnant? Don't Worry

(Philadelphia Inquirer/HealthDay News) Mar 29, 2017 - The cancer-preventing HPV vaccine does not appear to have any ill effect on babies unintentionally exposed to it in the womb, researchers report.

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Higher Cancer Deaths in Patients With Learning Difficulties

(Medscape Medical News) Mar 29, 2017 - The cancer-specific mortality rate was four-fold higher in patients with testicular cancer who also had learning difficulties than in those without.

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Adults with Disabilities Screened Less Often for Colorectal Cancer

(UM School of Medicine) Mar 28, 2017 - Researchers from the University of Missouri School of Medicine looked at screening adherence rates and found that individuals with certain disabilities are less likely to receive recommended preventive screenings.

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New Research Explains Why Even Targeted Therapies Eventually Fail In Lung Cancer

(CSHL) Mar 29, 2017 - The drug Tarceva (erlotinib), for example, can virtually erase all traces of aggressive lung cancer tumors in a subset of patients who bear a particular disease-driving mutation in a gene called EGFR.

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Progenics Pharmaceuticals Announces Positive Topline Results From Registrational Phase 2b Trial of AZEDRA®

(Yahoo! Finance) Mar 29, 2017 - Novel, targeted radiotherapeutic for malignant and/or recurrent pheochromocytoma and paraganglioma; study achieves primary endpoint; secondary endpoint shows favorable tumor response to therapy; company to submit NDA in mid-2017.

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Immunovaccine Announces Positive Interim Clinical Data from Ovarian Cancer Study of DPX-Survivac in Combination with Epacadostat

(Immunovaccine) Mar 29, 2017 - Immunovaccine Inc., a clinical stage vaccine and immunotherapy company, today announced the first interim data analysis from its ongoing Phase 1b clinical study of its novel T-cell activating immuno-oncology candidate, DPX-Survivac, in combination with epacadostat and low-dose cyclophosphamide.

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