Colorectal

IDEA Sets New Standard for Post-Surg Chemo

(SWOG) Mar 28, 2018 - Some stage III colon cancer patients can cut in half the number of chemotherapy treatments they receive after surgery, significantly reducing the costs, treatment time, and long-term toxic effects of chemotherapy, according to results of a unique global clinical trial collaboration published for the first time in the New England Journal of Medicine.

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High-flying Biotech Loxo Tempers Bullish View For Cancer Drug

(Reuters) Apr 3, 2018 - In record time, Loxo Oncology developed a novel drug for a wide variety of tumors that share a rare mutation. It recently struck a partnership with Germany’s Bayer. Its stock tripled in the past year.

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Cancer Docs Say 'Superblood' May Work Against Deadly Malignancies

(NBCNews.com) Apr 2, 2018 - New therapy seen as possible treatment for pancreatic cancer and triple-negative breast cancer, among others.

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Interactive App Improves Colorectal Cancer Screening Rates

(NCI/Cancer Currents Blog) Apr 9, 2018 - Colorectal cancer screening reduces deaths from the disease, yet about one-third of Americans aren’t up to date with screening. Learn what happened when people waiting for routine checkups used an app that allowed them to order their own screening test.

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Colon Cancer Chemo Could Be Halved After Surgery

(Cancer Research UK) Mar 28, 2018 - Chemotherapy courses after surgery could be cut in half for some colon cancer patients, according to a new global study.

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IARC Handbooks of Cancer Prevention Volume 17: Colorectal Cancer Screening

(IARC) Mar 27, 2018 - A Working Group of 23 independent international experts met at the International Agency for Research on Cancer (IARC) on 14–21 November 2017 to evaluate the effectiveness of various colorectal cancer screening methods. A summary of the outcome of the meeting is published today as a Special Report in The New England Journal of Medicine.

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Two Immunotherapies Used Together For The First Time To Tackle Tumors

(Augusta University/Jagwire News) Mar 26, 2018 - Two immunotherapies – one that enables the T-cells a patient already has to better attack a tumor and another that can produce an independent and vigorous immune response – are being given together for the first time to help more patients wage a stronger war on a wide range of solid tumors, researchers say.

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U.S. Food and Drug Administration (FDA) Accepts Bristol-Myers Squibb’s Application for Opdivo (nivolumab) Plus Yervoy (ipilimumab) for Previously Treated Patients with MSI-H or dMMR Metastatic Colorectal Cancer for Priority Review

(BMS) Mar 27, 2018 - Bristol-Myers Squibb Company today announced that the U.S. Food and Drug Administration (FDA) accepted its supplemental Biologics License Application (sBLA) for Opdivo (nivolumab) in combination with Yervoy (ipilimumab) for the treatment of adults with microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) metastatic colorectal cancer (mCRC) that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan.

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New Colon Cancer Finding Could Lead To Earlier Diagnosis -- And Better Outcomes

(OMRF) Mar 28, 2018 - For many years, physicians have puzzled over why people with "clean" colonoscopies went on to develop colon cancer. New findings from the Oklahoma Medical Research Foundation may help explain why, and the discovery could lead to ways to detect these cancers earlier and more effectively.

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Cancer Risk Rises as Patients Wait for Diagnostic Testing

(Penn Medicine) Apr 10, 2018 - Literature review finds increased risk of cancer, late stage cancer, and mortality with increasing wait time between a positive screening and start of diagnostic testing.

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Roche Pauses Tecentriq/Cotellic Cancer Trial After Four Patient Deaths

(BioPharma Dive) Apr 12, 2018 - Following the deaths of four patients, Roche said in a statement sent to BioPharma Dive that it has "made a decision to temporarily halt recruitment in the MODUL Phase 2 signal seeking study for metastatic colorectal cancer" following a recommendation from an independent data monitoring committee.

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Implant Will Show When Cancer Is Present By Generating Artificial Mole On Skin

(The Telegraph [UK]) Apr 18, 2018 - An implant which detects cancer in the body and causes a small artificial mole to appear on the skin as an early warning sign has been developed by scientists.

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Healthy Lifestyle Behaviors Linked to Lower Colon Cancer Mortality in Study

(American Cancer Society) Apr 18, 2018 - Researchers from major cancer centers across the US have found that colon cancer survivors who engaged in healthy lifestyle behaviors consistent with American Cancer Society guidelines lived longer than those who did not engage in those healthy behaviors.

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Bayer Unites with Patient Advocacy Groups to Raise Awareness about Colorectal Cancer

(MarketWatch) Apr 24, 2018 - Bayer is pleased to announce another year of partnership with patient advocacy organizations Colorectal Cancer Alliance (the Alliance) and Fight Colorectal Cancer (Fight CRC).

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New Study Shows Why Cancer Cost Planning Needs to Start Accounting for People Under 65

(NCCN) Apr 18, 2018 - A new study published in JNCCN – Journal of the National Comprehensive Cancer Network finds that cancer care costs in the United States are higher for people under age 65, and the costs increase with disease stage.

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Cancer Genetics’ Unique Tissue of Origin Test (TOO®) Receives Special FDA 510(k) Clearance

(Streetinsider) Apr 16, 2018 - Cancer Genetics, Inc., a leader in enabling precision medicine for oncology through molecular markers and diagnostics, today announced that it has received special 510(k) clearance from the U. S. Food and Drug Administration (FDA) for its Tissue of Origin test (TOO®) following modifications made to test reagents and software.

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Nutrition, Physical Activity Guidelines And Survival After Colon Cancer Diagnosis

(The JAMA Network) Apr 12, 2018 - Bottom Line: A lifestyle consistent with the American Cancer Society (ACS) guidelines to maintain a healthy weight, engage in regular physical activity, and eat a diet rich in nutritious foods was associated with a lower risk of death in patients with colon cancer.

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Are Supplements Giving You Cancer?

(New York Post) Apr 12, 2018 - Certain dietary iron supplements may aid the development of colon cancer in humans, according to new research out of Sweden’s Chalmers University of Technology.

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Taiho Oncology Presents Data on LONSURF® (trifluridine and tipiracil) and Key Investigational Compounds at the 109th Annual Meeting of the American Association for Cancer Research

(Taiho) Apr 13, 2018 - Taiho Oncology, Inc. today announced clinical data for LONSURF® (trifluridine and tipiracil, TAS-102) for the treatment of patients with advanced gastrointestinal tumors, and two investigational compounds, TAS-120 and TAS-114, both currently in clinical development for the treatment of patients with a variety of advanced solid tumors.

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Sigmoidoscopy Reduces Colon Cancer Risk For Men, But Not Women

(2 Minute Medicine) Apr 24, 2018 - The results of the study suggested that while sigmoidoscopy reduces colon cancer risk for men, this trend is not apparent in women.

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