Colorectal

Forgoing Chemotherapy Linked to Worse Survival in Older Patients With Advanced Colon Cancer Who had Dementia

(AACR) Sept 22, 2017 - A pre-existing diagnosis of dementia was associated with increased risk of death for older patients with advanced colon cancer; however, some of the effects of dementia on survival could be mediated by receipt of chemotherapy, according to results of a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

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Cancer Risk Doubled in Kids with IBD

(MedPage Today) Sept 20, 2017 - Children with inflammatory bowel disease (IBD) are at a twofold increased risk for cancer, although the absolute risks are low, a large Swedish study found.

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New Study Offers Novel Treatment Strategy for Patients with Colon Cancer

(Boston University School of Medicine) Sept 20, 2017 - Colorectal cancer is the fourth leading cause of cancer-related deaths worldwide. In a new study, researchers demonstrate for the first time that a previously uncharacterized protein is increased in colon cancer.

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Penn Researchers Identify New Target, Develop New Drug for Cancer Therapies

(Penn Medicine) Sept 20, 2017 - Opening up a new pathway to fight cancer, researchers at the University of Pennsylvania have found a way to target an enzyme that is crucial to tumor growth while also blocking the mechanism that has made past attempts to target that enzyme resistant to treatment.

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NUS Scientists Combine Antimalarial Drug With Light Sensitive Molecules For Promising Treatment Of Cancer

(National University of Singapore) Sept 18, 2017 - Artemisinin, a potent anti-malarial drug, has been widely hailed as a promising alternative cancer treatment. Scientists from the National University of Singapore (NUS) recently showed that its anti-cancer properties could be enhanced by 10 folds when used in combination with Aminolaevulinic acid (ALA), a photosensitiser or a drug which, upon exposure to light, leads to generation of free radicals that can kill cells.

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FDA Approves Amgen And Allergan's MVASI™ (bevacizumab-awwb) For The Treatment Of Five Types Of Cancer

(MarketWatch) Sept 14, 2017 - Amgen today announced that the U.S. Food and Drug Administration (FDA) has approved MVASI™ (bevacizumab-awwb) for all eligible indications of the reference product, Avastin [®] (bevacizumab).

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Amgen Is Taking On a $3 Billion Cancer Drug. But Will It Cut Costs for Patients?

(Fortune) Sept 15, 2017 - The Food and Drug Administration (FDA) continued its potentially record-breaking pace of new drug approvals Thursday, green lighting the first-ever "biosimilar" copycat of a cancer drug.

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FDA Approves First Biosimilar For The Treatment Of Cancer

(FDA.gov) Sept 14, 2017 - The U.S. Food and Drug Administration today approved Mvasi (bevacizumab-awwb) as a biosimilar to Avastin (bevacizumab) for the treatment of multiple types of cancer. Mvasi is the first biosimilar approved in the U.S. for the treatment of cancer.

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Best Poster at ESMO 2017 Shows Positive Trials Twice as Likely to be Reported in Lay Press

(ESMO 2017 Congress) Sept 12, 2017 - Randomised controlled trials with positive results are twice as likely to be reported by the lay press as those with negative trials, according to results from the Best Poster in Public Health and Health Economics at the ESMO 2017 Congress in Madrid.

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Debate on Duration of Colon Cancer Adjuvant Chemotherapy Takes Centre Stage at ESMO 2017

(ESMO 2017 Congress) Sept 11, 2017 - The debate on whether to shorten adjuvant chemotherapy for colon cancer from six to three months takes centre stage today in a special session at the ESMO 2017 Congress in Madrid.

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New Report Finds Whole Grains Lower Colorectal Cancer Risk, Processed Meat Increases Risk

(AICR) Sept 7, 2017 - Eating whole grains daily, such as brown rice or whole-wheat bread, reduces colorectal cancer risk, with the more you eat the lower the risk, finds a new report by the American Institute for Cancer Research (AICR) and the World Cancer Research Fund (WCRF).

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Some Stroke Survivors May Have Underlying Cancer

(ESMO 2017 Congress) Sept 6, 2017 - Some stroke survivors may have underlying cancer, according to an observational study to be presented at the ESMO 2017 Congress in Madrid.

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Gut Microbes May Promote Immune Responses Against Colorectal Cancer

(AACR) Sep 5, 2017 - Bacteria in the gut could stimulate tumor cells to produce factors that regulate cell mobility called chemokines that recruit T cells to the tumor, which is linked to improved outcomes, according to data presented at the Third CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 6-9.

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Expanding Germline Analyses to Prevent and Treat Cancers

(Medscape Medical News) Sept 6, 2017 - Precision medicine targets actionable mutations in tumors to appropriate therapies, but finding those mutations can be a challenge.

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Adipose Tissue May Affect Cancer Development In Multiple Ways

(AACR) Sep 1, 2017 - Adipose tissue, or fat, may influence the development of cancer in diverse ways, depending on the type of fat and the location in the body.

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Roche to Present New Data From Its Oncology Portfolio At The 2017 European Society For Medical Oncology (ESMO) Congress

(Roche) Aug 31, 2017 - Data from 18 approved and investigational cancer medicines to be presented at ESMO 2017; results for Zelboraf (vemurafenib) as an adjuvant treatment for BRAF V600 mutation-positive melanoma to feature in the ESMO Presidential Symposium; new data from phase III ALEX and ALUR studies provide additional evidence supporting the use of Alecensa (alectinib) for people with ALK-positive non-small cell lung cancer (NSCLC); multiple clinical, biomarker and real-world data studies across a range of tumour types enhance understanding of cancer.

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Bayer to Highlight New Research at ESMO 2017 Congress

(Yahoo! Finance) Sep 1, 2017 - Bayer will present the latest research from across its growing oncology portfolio at the European Society for Medical Oncology (ESMO) 2017 Congress, September 8-12 in Madrid, Spain.

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Merck KGaA, Darmstadt, Germany: Driving Innovation in Cancer Care at ESMO 2017 With New Data in Hard-to-Treat Cancers

(Yahoo! Finance) Aug 31, 2017 - Merck KGaA, Darmstadt, Germany , a leading science and technology company, today announced it will present data for a number of tumor types across its rapidly evolving pipeline.

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Bowel Cancer Study Reveals Impact Of Mutations On Protein Networks

(ICR [UK]) Aug 29, 2017 - For the first time, scientists have completed a detailed study of many of the proteins in bowel cancer cells.

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Palliative Care Can Substantially Decrease Healthcare Utilization in Patients with Advanced Cancer, New Study Shows

(ASCO) Aug 22, 2017 - A new population-based study shows that palliative care substantially decreased healthcare utilization among Medicare beneficiaries with advanced cancer, resulting in less intensive care being delivered at the end of life.

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