Study Shows New Second Line Therapy for Metastatic Colorectal Cancer is Effective and Safe

(ESMO Asia 2017 Congress) Nov 18, 2017 - A randomised trial in 650 patients has confirmed the safety and efficacy of a new second line treatment for metastatic colorectal cancer, researchers report at the ESMO Asia 2017 Congress.

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CIRCULOGENE Introduces Single-Tube, Blood-Based Microsatellite Instability (MSI) Biomarker Testing for Multiple Cancers

(Yahoo! Finance) Nov 16, 2017 - CIRCULOGENE, a leading liquid biopsy company advancing precision medicine through personalized molecular genetics testing, has announced the availability of microsatellite instability (MSI) biomarker testing for multiple cancer types.

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Tom Marsilje, Cancer Researcher, Patient And Advocate, Dies at 45

( Nov 15, 2017 - Tom Marsilje, the oncology researcher whose late-stage colon cancer diagnosis turned him into an internationally known patient advocate and prolific writer, died Tuesday after a five-year fight against the disease.

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FDA Clears Group Of Cancer Tests Developed By Roche In Oro Valley

(Arizona Daily Star) Nov 14, 2017 - The U.S. Food and Drug Administration has cleared a group of tests for colorectal cancer developed by Roche Group member Ventana Medical Systems in Oro Valley.

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Roche Receives FDA Clearance for the VENTANA MMR IHC Panel for Patients Diagnosed with Colorectal Cancer

(Roche) Nov 14, 2017 - Roche today announced US Food & Drug Administration (FDA) clearance of the VENTANA MMR IHC Panel, which provides clinicians with a comprehensive group of immunohistochemistry (IHC) tests for patients diagnosed with colorectal cancer.

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Quality Of Care For Older Texas Patients With Colon Cancer On The Rise, Still Room For Improvement

(MD Anderson) Nov 15, 2017 - Research from The University of Texas MD Anderson Cancer Center finds adherence to surgical treatment guidelines has improved significantly among older Texas patients with colon cancer since 2001, while adherence to chemotherapy guidelines has remained largely unchanged.

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Differences in Insurance Coverage Associated with Nearly Half of Black-White Survival Disparity in Colorectal Cancer

(ACS) Nov 14, 2017 - Health insurance coverage differences account for nearly one-half of the black-white survival disparity in colorectal cancer patients, according to a new study.

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Use of MMR Deficiency Testing in Younger CRC Patients Is Low

(Physician’s Weekly/HealthDay News) Nov 13, 2017 - Fewer than half of younger adults with colorectal cancer (CRC) undergo mismatch repair (MMR) deficiency of DNA testing, according to a study published online Nov. 9 in JAMA Oncology.

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In a Sea Of Bowel Bugs, Another Species That Makes Colon Cancer Grow

(STAT Plus/In the Lab) Nov 13, 2017 - For decades, doctors have made a curious observation: people stricken with a particular heart or blood infection often developed colorectal cancer.

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Cancer Doctors Cite Risks of Drinking Alcohol

(New York Times/Well blog) Nov 7, 2017 - The American Society of Clinical Oncology, which represents many of the nation’s top cancer doctors, is calling attention to the ties between alcohol and cancer. In a statement published Tuesday in the Journal of Clinical Oncology, the group cites evidence that even light drinking can slightly raise a woman’s risk of breast cancer and increase a common type of esophageal cancer.

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Alcohol Linked to Cancer According to Major Oncology Organization: ASCO Cites Evidence and Calls for Reduced Alcohol Consumption

(ASCO) Nov 7, 2017 - Alcohol use—whether light, moderate, or heavy—is linked with increasing the risk of several leading cancers, including those of the breast, colon, esophagus, and head and neck, according to evidence gathered by the American Society of Clinical Oncology (ASCO).

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Eating More Fiber Tied To Lower Mortality With Colon Cancer

(Reuters Health) Nov 6, 2017 - People who eat a high-fiber diet or increase their fiber intake after a colon cancer diagnosis may be less likely to die of these tumors than individuals who don’t consume much fiber, a recent study suggests.

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Huntsman Cancer Institute Study Identifies Enhanced Impact of Treatment for Hereditary Cancer Patients

(HCI) Nov 6, 2017 - People with an inherited syndrome called familial adenomatous polyposis (FAP) have a 100% lifetime risk of developing colorectal cancer if they do not seek appropriate medical care.

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Drug For Chemo-Induced Neuropathy Shows Promise

(MedPage Today) Nov 3, 2017 - A novel agent to prevent chemotherapy-induced neuropathy demonstrated evidence of efficacy in a phase IIb placebo-controlled clinical trial.

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New System for Treating Colorectal Cancer Can Lead to Complete Cure

(SNMMI) Nov 2, 2017 - Researchers at Memorial Sloan Kettering Cancer Center in New York City and Massachusetts Institute of Technology in Boston have developed a new, three-step system that uses nuclear medicine to target and eliminate colorectal cancer.

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Exact Sciences Plots Expansion Strategy as Cancer Test Sales Boom

(Xconomy Wisconsin) Oct 31, 2017 - CEO Kevin Conroy said the next opportunity his company sees “to use the power” of Exact’s development platform is a test designed to assess potentially cancerous nodules, or clumps of cells, found in the lungs. “The potential for a new blood-based biomarker test [for lung cancer] is significant,” Conroy said.

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UEG Week: Colorectal Cancer Screening Should Start At 45, New Research Shows

(25th UEG Week) Oct 30, 2017 - Screening for colorectal cancer (CRC) should begin at 45 years of age to match rising mortality rates in young adults, research presented today at the 25th UEG Week Barcelona reveals.

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UEG Week: Artificial Intelligence: Is This The Future Of Early Colorectal Cancer Detection?

(25th UEG Week) Oct 30, 2017 - A new endoscopic system powered by artificial intelligence (AI) has today been shown to automatically identify colorectal adenomas during colonoscopy. The system, developed in Japan, has recently been tested in one of the first prospective trials of AI-assisted endoscopy in a clinical setting, with the results presented today at the 25th UEG Week in Barcelona, Spain.

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Colorectal Cancers May Mutate to Escape Immune System Detection in Many Ways

(2017 AACR-NCI-EORTC) Oct 27, 2017 - Whole exome sequencing revealed that colorectal cancers with high mutational load (MSI-H) predominantly use “immunoediting” to escape immune surveillance while colorectal cancers with low mutational load (MSS) use oncogenic signaling to escape from the immune response, according to new data.

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New Colorectal Cancer Test Could Detect Early Cancer-causing Genetic Biomarkers with High Degree of Sensitivity

(2017 AACR-NCI-EORTC) Oct 27, 2017 - An investigational test that screens for colorectal cancer could detect genetic mutations that are indicative of the disease with a high degree of sensitivity and specificity, according to results of a new study.

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