Archived News Headlines

We have been archiving all OBR daily news stories since March 2008. Use the box below to search our archives for specific articles and content. Please note: we do not "host" news articles on our website. When a media source removes an article from their website the link becomes inactive, and you will only be able to see the date, title, first sentence and media source that published the article.

Retention of One Normal Version of BRCA Gene in Breast and Ovarian Cancers Influences Patient Survival, According to Penn-led Study

(Penn Medicine) Aug 22, 2017 - Researchers in the Perelman School of Medicine at the University of Pennsylvania found a relationship between the genetics of tumors with germline BRCA1/2 mutations and whether the tumor retains the normal copy of the BRCA1/2 gene, and risk for primary resistance to a common chemotherapy.

PAREXEL and Osaka International Cancer Institute Form Alliance to Advance Clinical Research in Japan

(TheStreet) Aug 21, 2017 - The partnership will aim to drive greater efficiencies in support of patient recruitment for clinical trials in oncology and hematology, accelerating the development of innovative and effective new cancer treatments for patients.

Searching for the ‘Signature’ Causes of BRCAness in Breast Cancer

(Broad Institute) Aug 21, 2017 - A mutation pattern or 'signature' linked to defects in 2 genes points to other ways an important DNA repair mechanism can be shut off in breast cancer.

The Battle Over the Federal 340B Drug Program

(Axios) Aug 21, 2017 - A federal advisory panel on Monday recommended Medicare scrap a proposal that would slash drug payments to hospitals under the 340B drug pricing program by almost 30 percentage points next year.

Blood Test Predicts Prostate Tumor Resistance

(TUM [Munich, Germany]) Aug 22, 2017 - A new blood test developed by researchers at the Technical University of Munich (TUM) can predict drug resistance in patients with advanced prostate cancer.

Ironwood Wins OK For An Easier-To-Administer Gout Treatment

(Boston Globe) Aug 21, 2017 - It’s the most common form of inflammatory arthritis in adults, often first appears as a painfully swollen big toe, and used to be called the “rich man’s disease,” because sufferers frequently consumed lots of meat, seafood, and alcohol: gout.

Zebrafish Implanted With A Cancer Patient’s Tumor Could Guide Cancer Treatment

(Science Magazine) Aug 21, 2017 - This week, researchers at the Champalimaud Centre for the Unknown in Lisbon reported growing implanted human tumor cells in zebrafish larvae. Each fish became a minuscule model of a patient’s cancer—and a testbed for treatments.

PCSK9 Inhibitors Still Too Pricey, Study Finds

(BioPharma Dive) Aug 22, 2017 - New research published online Tuesday found Amgen, Inc.'s Repatha would need significant price reductions in order to meet a measure of cost-effectiveness for certain patients — even when taking into account the proven cardiovascular benefit of the PCSK9 inhibitor shown in the company's FOURIER outcomes trial.

Opinion: On Drug Pricing: FDA Backs Up Its Calls for Increased Competition

(Xconomy San Diego) Aug 21, 2017 - FDA Commissioner Scott Gottlieb has been very public in expressing his desire to provide increased competition and greater choice to American consumers in a bid to drive down prices of prescription medicines. Recently, the agency he oversees took some unusual steps to back up those statements with action.

FDA to Evaluate Children’s Cough Medicine Containing Opioids

(STAT) Aug 21, 2017 - A federal committee will meet in three weeks to consider whether cough medicine containing certain opioids should be prescribed to children, the Food and Drug Administration announced Monday.