Oncology Corporate Profile
Cold Genesys, Inc. is a privately-held, clinical-stage oncolytic viral immunotherapy company with its lead product CG0070 now in an integrated Phase II/III clinical trial for bladder cancer. CG0070 is a conditionally replication-competent adenovirus, containing an E2F promoter in the viral E1A region that drives the expression of GM-CSF. CGI also has developed n-dodecyl-D-maltoside to specifically enhance viral transduction in cancer cells. CG0070 was previously tested in a Phase I/II trial of 35 patients with non-muscle invasive bladder cancer in 2008.
|Brand / Product||Class||Area of Study||Phase||Partnership|
|CG0070||oncolytic virus||Bladder cancer||III|
|CG0070 (+ immune checkpoint moduator)||oncolytic virus||Bladder cancer||I|
|CG0070 (+ immune checkpoint moduator)||oncolytic virus||Various cancer types||I|
|CG0161||anti-CTLA-4 antibody||Various cancer types||Preclinical|
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