Video Center


The OBR Video Center Features educational videos covering a wide range of oncology specific topics.

Will Tomorrow's CAR-T Therapy Innovations Solve Today's Challenges?

Sharon Karlsberg, Principal, Oncology, ZS Associates, considers the future of CAR-T therapies with Michael R. Bishop, MD, Professor of Medicine, Director, Hematopoietic Stem Cell Transplantation Program, University of Chicago.

Published: 03 July 2018

Recent Videos: ASCO Conference Coverage

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Will Tomorrow's CAR-T Therapy Innovations Solve Today's Challenges?

Sharon Karlsberg, Principal, Oncology, ZS Associates, considers the future of CAR-T therapies with Michael R. Bishop, MD, Professor of Medicine, ...

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How Can Manufacturers Help Institutions Prepare for CAR-T Therapies?

Sharon Karlsberg, Principal, Oncology, ZS Associates, considers how manufacturers can help institutions prepare for CAR-T therapies with Michael R. Bishop, ...

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How Can a CAR-T Center Get Established and Effectively Treat Patients?

Sharon Karlsberg, Principal, Oncology, ZS Associates, discusses how a CAR-T center becomes established and effectively treats patients with Michael R. ...

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Sai-Hong Ignatius Ou, MD, PhD, comments on Tumor Mutation Burden (TMB) as a biomarker in NSCLC

Dr. Ou considers whether Tumor Mutation Burden (TMB) is a valid biomarker in determining non-small cell lung cancer (NSCLC) patients ...

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Sai-Hong Ignatius Ou, MD, PhD, on pemetrexed maintenance therapy

Dr. Ou provides opinion on whether he would continue pemetrexed maintenance after successful treatment of a patient with carboplatin, pemetrexed, ...

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Sai-Hong Ignatius Ou, MD, PhD, discusses key takeaways from the IMpower150 study at ASCO 2018

Dr. Ou elaborates on the key takeaways from the IMpower150 study in non-small cell lung cancer (NSCLC) and whether the ...

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Sai-Hong Ignatius Ou, MD, PhD, comments on combo chemotherapy & immunotherapy in 2nd line NSCLC

Dr. Ou offers opinion on how chemotherapy should be combined with immunotherapy in the treatment of 2nd line non-small cell ...

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Sai-Hong Ignatius Ou, MD, PhD, regarding combo chemotherapy & immunotherapy in 1st line NSCLC

Dr. Ou discusses outcomes from Keynote 189, specifically, how chemotherapy should be combined with immunotherapy in the treatment of 1st ...

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Sai-Hong Ignatius Ou, MD, PhD, on testing for PD-L1 expression in NSCLC

Dr. Ou offers opinion on whether every non-small cell lung cancer (NSCLC) patient should be tested for PD-L1 expression and ...

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Benjamin Philip Levy, MD, on Tumor Mutation Burden (TMB) as a biomarker in NSCLC

Dr. Levy elaborates on whether Tumor Mutation Burden (TMB) is a valid biomarker to determine those non-small cell lung cancer ...

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How Can Manufacturers Help Institutions Prepare for CAR-T Therapies?

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How Can a CAR-T Center Get Established and Effectively Treat Patients?

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Sai-Hong Ignatius Ou, MD, PhD, comments on Tumor Mutation Burden (TMB) as a biomarker in NSCLC

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Sai-Hong Ignatius Ou, MD, PhD, on pemetrexed maintenance therapy

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Sai-Hong Ignatius Ou, MD, PhD, discusses key takeaways from the IMpower150 study at ASCO 2018

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Sai-Hong Ignatius Ou, MD, PhD, comments on combo chemotherapy & immunotherapy in 2nd line NSCLC

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Sai-Hong Ignatius Ou, MD, PhD, regarding combo chemotherapy & immunotherapy in 1st line NSCLC

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Sai-Hong Ignatius Ou, MD, PhD, on testing for PD-L1 expression in NSCLC

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Benjamin Philip Levy, MD, on Tumor Mutation Burden (TMB) as a biomarker in NSCLC

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Benjamin Philip Levy, MD, on maintenance therapy following carboplatin, pemetrexed & pembrolizumab

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Benjamin Philip Levy, MD, comments on the IMpower150 clinical trial in NSCLC

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Benjamin Philip Levy, MD, on options for NSCLC patients who progress on 1st line I-O & chemotherapy

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Benjamin Philip Levy, MD, regarding combo chemotherapy & immunotherapy in 2nd line NSCLC

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Benjamin Philip Levy, MD, discusses the practice-changing outcomes from Keynote 189

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Benjamin Philip Levy, MD, offers opinion on testing for PD-L1 expression in NSCLC

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Novel Endpoints: Working Through Today's Challenges to Improve the Future of Cancer Care

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Novel Endpoints in Cancer Care: What Lies Ahead

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Oncology Clinical Trials: Why We're Searching for Emerging Endpoints

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Howard (Jack) West, MD, regarding Tumor Mutation Burden (TMB) as a biomarker for NSCLC patients

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Howard (Jack) West, MD, on maintenance therapy after carboplatin, pemetrexed & pembrolizimab

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NGS and Cancer: Combatting the Hazards of Misinformation

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Will NGS-Based Cancer Tests Become Routine?

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Next-Gen Sequencing is Transforming Oncology Practices

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Howard (Jack) West, MD, discusses key takeaways from the IMpower150 study in NSCLC

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Howard (Jack) West, MD, on treatment options for patients who progress on I-O & chemotherapy

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Howard (Jack) West, MD, regarding the combination of immunotherapy & chemotherapy in NSCLC

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Howard (Jack) West, MD, regarding PDL-1 expression and NSCLC

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Howard A. "Skip" Burris III, MD, FACP, FASCO, considers predictive biomarkers in NSCLC

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Howard A. "Skip" Burris III, MD, FACP, FASCO, comments on the TAILORx study from ASCO 2018

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Howard A. "Skip" Burris III, MD, FACP, FASCO, on the outcomes of the PERSEPHONE clinical trial

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Howard A. "Skip" Burris III, MD, FACP, FASCO, regarding novel concepts in clinical trial design

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Howard A. "Skip" Burris III, MD, FACP, FASCO, shares his goals for the 2019 ASCO Annual Meeting

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Neelima Denduluri, MD, on the outcomes of the SANDPIPER study presented at ASCO 2018

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Neelima Denduluri, MD, looks back on the Short-HER trial from the 2017 ASCO Annual Meeting

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Neelima Denduluri, MD, offers opinion on the PERSEPHONE trial in early HER2+ breast cancer

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Neelima Denduluri, MD, tells us about the recent updates to breast cancer guidelines

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Neelima Denduluri, MD, comments on the role of CDK4/6 inhibitors

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Neelima Denduluri, MD, regarding the implications of the TAILORx study from ASCO 2018

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Robert A. Figlin, MD, on the convenience factor of oral TKIs & treatment decisions in advanced RCC

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Robert A. Figlin, MD, on the trade-offs between safety & efficacy when discussing 1st line RCC

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Robert A. Figlin, MD, provides perspective on I-O failures

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Robert A. Figlin, MD, on deciding which metastatic RCC patients should get a TKI as 1st line therapy

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Robert A. Figlin, MD, on how checkpoint inhibitors figure into treatment for 1st line RCC patients

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Walter Stadler, MD, on therapies for high-volume, metastatic castration-resistant prostate cancer

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Walter Stadler, MD, on immunotherapy and prostate cancer treatment algorithms

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Walter Stadler, MD, comments on the PROSPER & SPARTAN studies in prostate cancer

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Walter Stadler, MD, regarding TKIs in the treatment of renal cell carcinoma

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Walter Stadler, MD, on treating RCC in the 2nd line setting following I-O failure

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Walter Stadler, MD, considers which mRCC patients should receive a TKI as 1st line therapy

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David I. Quinn, MD, provides perspective on the trade-offs between safety & efficacy in 1st line RCC

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David I. Quinn, MD, considers whether the convenience of oral TKIs impacts RCC treatment

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David I. Quinn, MD, comments on 2nd line therapy options following I-O failure

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David I. Quinn, MD, shares thoughts on Keynote 427 from the 2018 ASCO Annual Meeting

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David I. Quinn, MD, regarding the most exciting RCC data coming out of ASCO 2018

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Jeanny B. Aragon-Ching, MD, FACP, shares how checkpoint inhibitors fit into RCC treatment algorithms

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Jeanny B. Aragon-Ching, MD, FACP, comments on 2nd line treatment options in RCC after I-O failure

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Jeanny B. Aragon-Ching, MD, FACP, on response rates for erdafitinib in metastatic bladder cancer

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Jeanny B. Aragon-Ching, MD, FACP, on molecular markers in high-risk muscle-invasive bladder cancer

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Jeanny B. Aragon-Ching, MD, FACP, discusses new guidelines in treatment of metastatic bladder cancer

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Jeanny B. Aragon-Ching, MD, FACP, regarding the impact of the PROSPER and SPARTAN clinical trials

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Mohammad Jahanzeb, MD, FACP, discusses the significance of Keynote 42 from ASCO 2018

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Mohammad Jahanzeb, MD, FACP, regarding pemetrexed maintenance therapy

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Mohammad Jahanzeb, MD, FACP, on the results of Keynote 189, PDL-1 expression and patient selection

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Eunice Wang, MD, tells us about the most exciting data coming out of the 2018 ASCO Annual Meeting

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Eunice Wang, MD, on the role of nivolumab maintenance in high-risk AML patients

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Eunice Wang, MD, regarding evolving treatment considerations for FLT3 mutated AML

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Eunice Wang, MD, shares what we've learned about gilteritinib since the 2017 ASCO Annual Meeting

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Eunice Wang, MD, considers the potential impact of gilteritinib in patients with FLT3-ITD AML

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Eunice Wang, MD, on next-generation sequencing and treatment selection in AML

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Neelima Denduluri, MD, speculates on the implications of taselisib data at ASCO 2018

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Neelima Denduluri, MD, on the MONALEESA-3 study in HR+/HER2- advanced breast cancer

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Neelima Denduluri, MD, considers whether the results of TAILORx are practice-changing

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Gary D. Steinberg, MD, on whether FGFR inhibitors have the potential to be practice-changing

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Bobby Green, MD, on next-generation sequencing and Flatiron's clinico-genomic database

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Bobby Green, MD, shares an update on Flatiron’s clinico-genomic database

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Bobby Green, MD, reflects on the 2018 ASCO Annual Meeting

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Ghassan Abou-Alfa, MD, MBA, regarding the shortcomings of the RECIST study in HCC

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Ghassan Abou-Alfa, MD, MBA, shares the outcomes of the CELESTIAL study from ASCO 2018

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Ghassan Abou-Alfa, MD, MBA, considers how immunotherapies should be combined with TKIs

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Ghassan Abou-Alfa, MD, MBA, on the latest in systemic therapy for advanced HCC

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Atrayee Basu Mallick, MD, shares highlights from the 2018 ASCO Annual Meeting

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Atrayee Basu Mallick, MD, considers how tumor-sidedness impacts CRC treatment algorithms

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Atrayee Basu Mallick, MD, discusses how nivolumab is incorporated into mCRC treatment algorithms

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Atrayee Basu Mallick, MD, tells us about the outcomes of the Checkmate 142 study in mCRC

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Atrayee Basu Mallick, MD, on the addition of vemurafenib to the NCCN guidelines for mCRC

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Atrayee Basu Mallick, MD, regarding the impact of stage & mismatch repair status on CRC treatment

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Atrayee Basu Mallick, MD, offers opinion on immunotherapy in colorectal cancer

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John Leighton, MD, on the headline “Immunotherapy Now Standard for Some Patients With CRC”

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John Leighton, MD, regarding preoperative chemotherapy in resectable pancreatic cancer

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John Leighton, MD, regarding the PA.6 clinical study presented at ASCO 2018

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John Leighton, MD, explains how tumor sidedness impacts CRC treatment algorithms

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John Leighton, MD, comments on the outcomes of Checkmate 142 in mCRC

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Howard Hochster, MD, regarding the outcomes of the PRODIGY7 study in mCRC

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Howard Hochster, MD, comments on the VALENTINO study presented at ASCO 2018

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Howard Hochster, MD, tells us about the outcomes of ECOG-7208 in 2nd line mCRC

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Primo N. Lara, Jr., MD, comments on which TKIs appear most effective in 1st line RCC

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Primo N. Lara, Jr., MD, on whether the convenience of oral TKIs influences treatment decisions

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Primo N. Lara, Jr., MD, considers the trade-offs between safety & efficacy in 1st line RCC treatment

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Primo N. Lara, Jr., MD, regarding the treatment path following I-O failure

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Primo N. Lara, Jr., MD, on deciding which mRCC patients should receive a TKI

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Primo N. Lara, Jr., MD, on how checkpoint inhibitors fit into RCC treatment algorithms

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Celestia S. Higano, MD, considers the role of immunotherapy in prostate cancer

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Celestia S. Higano, MD, discusses outcomes from the PROSPER and SPARTAN studies at ASCO 2018

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Edgardo S. Santos, MD, FACP, on the benefits of combination docetaxel + ramucirumab

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Edgardo S. Santos, MD, FACP, regarding pemetrexed maintenance therapy

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Edgardo S. Santos, MD, FACP, on the outcomes of Keynote 189 in metastatic NSCLC

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Edgardo S. Santos, MD, FACP, discusses exciting developments out of ASCO 2018

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Brian I. Rini, MD, FACP, comments on the CARMENA study presented at ASCO 2018

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Brian I. Rini, MD, FACP, discusses the influence of the convenience of oral TKIs

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Brian I. Rini, MD, FACP, regarding the trade-offs between safety & efficacy in 1st line RCC

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Brian I. Rini, MD, FACP, considers 2nd line treatment in advanced RCC following I-O failure

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Brian I. Rini, MD, FACP, on which metastatic RCC patients should receive a TKI as 1st line therapy

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Brian I. Rini, MD, FACP, on how checkpoint inhibitors figure into treatment algorithms for RCC

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James A. Posey III, MD, on the outcomes of the LAPACT study in locally advanced pancreatic cancer

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James A. Posey III, MD, comments on the impact of immunotherapy agents in pancreatic cancer

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James A. Posey III, MD, discusses the unmet medical needs in pancreatic ductal adenocarcinoma

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James A. Posey III, MD, offers opinion on preoperative chemotherapy in resectable pancreatic cancer

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James A. Posey III, MD, on the results and implications of the PA.6 clinical trial from ASCO 2018

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Ivo Abraham, PhD, RN, comments on how we can demonstrate the value of cancer treatments

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Ivo Abraham, PhD, RN, outlines biosimilar pricing and reimbursement

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Ivo Abraham, PhD, RN, discusses those biosimilars that are approved or close to approval

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Ivo Abraham, PhD, RN, speculates on the hurdles that could prevent the adoption of biosimilars

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Ivo Abraham, PhD, RN, explains the key features of a biosimilar

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Randall A. Oyer, MD, considers the work being done to address disparities in healthcare

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Randall A. Oyer, MD, provides information on the ACCC Immuno-Oncology Institute

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Randall A. Oyer, MD, explains how ACCC is interpreting the data on genetics presented at ASCO 2018

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Roy S. Herbst, MD, PhD, discusses the benefits of using ramucirumab plus docetaxel in 2nd line NSCLC

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Roy S. Herbst, MD, PhD, discusses drug sequencing as a result of Keynote 189 and 42 results

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Roy S. Herbst, MD, PhD, on if patient selection will change as a result of Keynote 42

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Roy S. Herbst, MD, PhD, on pemextrexed maintenance treatment

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Roy S. Herbst, MD, PhD, shares what's exciting here at ASCO 2018

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Roy S. Herbst, MD, PhD, on if Keynote 189 impacted view of PDL-1 expression and patient selection

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Lisa Rometty on the collaboration between Watson and the VA Precision Oncology Program

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Lisa Rometty shares some of the recent accomplishments of IBM's Watson

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Lisa Rometty elaborates on Watson's role in clinical trial matching

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Lisa Rometty regarding the impact of Watson on real-world evidence and clinical decision making

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Lisa Rometty explains how augmented intelligence is helping oncologists better treat cancer patients

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Julie Gralow, MD, speculates on taselisib as a standard of care based on the results of SANDPIPER

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Julie Gralow, MD, tells us about the SANDPIPER proof of concept trial presented at ACSO 2018

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Julie Gralow, MD, comments on the practice-changing implications of the TAILORx study

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Julie Gralow, MD, discusses outcomes from the TAILORx study presented at ASCO 2018

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Julie Gralow, MD, regarding the reduction in cardiac events in the PERSEPHONE study

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Julie Gralow, MD, reflects on the PERSEPHONE trial from the 2018 ASCO Annual Meeting

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Julie Gralow, MD, on the implications of the PERSEPHONE trial in early HER2+ breast cancer

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Julie Gralow, MD, speaks to the significance of the MONALEESA-3 study

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Julie Gralow, MD, elaborates on how to differentiate CDK4/6 inhibitors

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Tomasz M. Beer, MD, on how immunotherapy is being integrated into CRPC treatment algorithms

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Tomasz M. Beer, MD, on how the PROSPER and SPARTAN studies are impacting standard of care

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Tomasz M. Beer, MD, discusses the latest trends in the multimodality treatment of prostate cancer

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Tomasz M. Beer, MD, on how to avoid under-diagnosing and over-diagnosing prostate cancer

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Tomasz M. Beer, MD, discusses the central themes regarding prostate cancer here at ASCO 2018

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Mark Levis, MD, PhD, discusses exciting data from the 2018 ASCO Annual Meeting

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Mark Levis, MD, PhD, speculates on evolving treatment considerations for FLT3 mutated AML

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Mark Levis, MD, PhD, discusses what we've learned about gilteritinib in FLT3 mutated AML patients

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Mark Levis, MD, PhD, comments on measurable residual disease in relapsed/refractory AML

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Mark Levis, MD, PhD, on factors influencing 1st line therapy in AML patients with FLT3 mutations

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Mark Levis, MD, PhD, regarding the impact of next-generation sequencing in AML

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Nicholas J. Vogelzang, MD, on imaging as an effective solution for prostate cancer diagnosis

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Nicholas J. Vogelzang, MD, offers opinion on how MRI has improved diagnosing in prostate cancer

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Nicholas J. Vogelzang, MD, on how we can avoid under-diagnosing & over-diagnosing prostate cancer

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Richard Goldberg, MD, on the headline, "Immunotherapy Now Standard for Some Patients With CRC"

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Richard Goldberg, MD, elaborates on the outcomes of the PRODIGY7 study in mCRC patients

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Richard Goldberg, MD, on how the FIRE-3 data in CRC presented at ASCO 2018 reinforces CALGB 80405

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Richard Goldberg, MD, considers the value of preoperative chemotherapy in pancreatic cancer

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Richard Goldberg, MD, regarding the outcomes of the PA.6 clinical study in pancreatic cancer

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Jennie Crews, MD, MMM, FACP, regarding key initiatives for the ACCC Immuno-Oncology Institute

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Joan Schiller, MD, regarding Keynote trials from ASCO 2018 & the influence on choice of therapy

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Joan Schiller, MD, considers the validity of Tumor Mutation Burden (TMB) as a biomarker

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Joan Schiller, MD, on the impact of Keynotes 189 & 42 on drug sequencing regimens

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Joan Schiller, MD, regarding the results of Keynote 42 presented at the 2018 ASCO Annual Meeting

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Joan Schiller, MD, considers the continuation of pemetrexed maintenance

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Joan Schiller, MD, offers her opinion on Keynote 189 & PDL-1 expression and patient selection

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Jennie Crews, MD, MMM, FACP, outlines the mission of the ACCC Immuno-Oncology Institute

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Douglas W. Blayney, MD, discusses the biggest takeaway regarding breast cancer here at ASCO 2018

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Douglas W. Blayney, MD, on if the results of the TAILORx study practice changing

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Douglas W. Blayney, MD, discusses the implications of the TAILORx study

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Douglas W. Blayney, MD, discusses the MONALEESA-3 study in HR+/HER2- advanced breast cancer

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Douglas W. Blayney, MD, on differentiating CDK4/6 Inhibitors and if they can be used interchangeably

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Al Benson III, MD, FACP, on how tumor-sidedness impacts colorectal cancer treatment algorithms

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Al Benson III, MD, FACP, discusses the role of I-O and immunotherapy combinations when treating CRC

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Al Benson III, MD, FACP, tells us about the outcomes of the ECOG-ACRIN study

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Jennie Crews, MD, MMM, FACP, on how community oncology is embracing biomarkers

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Noa Biran, MD, on combination carfilzomib & daratumumab in revlimid-refractory multiple myeloma

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Noa Biran, MD, considers whether VPd is effective in relapsed multiple myeloma

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Noa Biran, MD, on the logistics involved in delivering CAR-T in the BB2121 study

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Noa Biran, MD, on the impact of the BB2121 study in multiple myeloma

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Noa Biran, MD, shares some of the exciting clinical advances presented at ASCO 2018

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Sara M. Tolaney, MD, MPH on whether CDK4/6 inhibitors can be used interchangeably

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Sara M. Tolaney, MD, MPH tells us about the outcomes of the MONARCH 2 study

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David R. Gandara, MD, discusses drug sequencing as a result of Keynote 189 and 42 results

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David R. Gandara, MD, on what will change about patient selection as a result of Keynote 42

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David R. Gandara, MD, on continuing pemextrexed maintenance

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David R. Gandara, MD, on whether Keynote 189 impacted view of PDL-1 expression and patient selection

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David R. Gandara, MD, shares the benefits of using ramucirumab plus docetaxel in 2nd line NSCLC

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David R. Gandara, MD, discusses exciting new developments in lung cancer here at ASCO 2018

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Mohammad Jahanzeb, MD, FACP, discusses the impact of Keynote 189 & 42 on drug sequencing regimens

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David I. Quinn, MD, on which metastatic RCC patients should receive a TKI as first-line therapy

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Gary D. Steinberg, MD, discusses FGFR inhibitors in metastatic bladder cancer

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Sara M. Tolaney, MD, MPH discusses the practice changing outcomes of the TAILORx study

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Sara M. Tolaney, MD, MPH, discusses the fulvestrant + ribociclib arm of the MONALEESA-3 study

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Sara M. Tolaney, MD, MPH, on whether the results of the TAILORx study are “practice changing”

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Celestia S. Higano, MD, discusses new data being presented here at ASCO in metastatic CRPC

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Celestia S. Higano, MD, discusses how MRI has improved the diagnosis of prostate cancer

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Celestia S. Higano, MD, on imaging as a cost-effective solution for diagnosis of prostate cancer

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Al Benson, MD, on what molecular markers are most important to test for when treating CRC patients