Video Center


The OBR Video Center Features educational videos covering a wide range of oncology specific topics.

Sai-Hong Ignatius Ou, MD, PhD, on testing for PD-L1 expression in NSCLC

Dr. Ou offers opinion on whether every non-small cell lung cancer (NSCLC) patient should be tested for PD-L1 expression and what levels of PD-L1 expression are actionable

Published: 27 June 2018

Recent Videos: Lung (includes NSCLC, SCLC, Mesothelioma)

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Sai-Hong Ignatius Ou, MD, PhD, comments on Tumor Mutation Burden (TMB) as a biomarker in NSCLC

Dr. Ou considers whether Tumor Mutation Burden (TMB) is a valid biomarker in determining non-small cell lung cancer (NSCLC) patients ...

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Sai-Hong Ignatius Ou, MD, PhD, on pemetrexed maintenance therapy

Dr. Ou provides opinion on whether he would continue pemetrexed maintenance after successful treatment of a patient with carboplatin, pemetrexed, ...

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Sai-Hong Ignatius Ou, MD, PhD, discusses key takeaways from the IMpower150 study at ASCO 2018

Dr. Ou elaborates on the key takeaways from the IMpower150 study in non-small cell lung cancer (NSCLC) and whether the ...

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Sai-Hong Ignatius Ou, MD, PhD, comments on combo chemotherapy & immunotherapy in 2nd line NSCLC

Dr. Ou offers opinion on how chemotherapy should be combined with immunotherapy in the treatment of 2nd line non-small cell ...

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Sai-Hong Ignatius Ou, MD, PhD, regarding combo chemotherapy & immunotherapy in 1st line NSCLC

Dr. Ou discusses outcomes from Keynote 189, specifically, how chemotherapy should be combined with immunotherapy in the treatment of 1st ...

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Sai-Hong Ignatius Ou, MD, PhD, on testing for PD-L1 expression in NSCLC

Dr. Ou offers opinion on whether every non-small cell lung cancer (NSCLC) patient should be tested for PD-L1 expression and ...

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Benjamin Philip Levy, MD, on Tumor Mutation Burden (TMB) as a biomarker in NSCLC

Dr. Levy elaborates on whether Tumor Mutation Burden (TMB) is a valid biomarker to determine those non-small cell lung cancer ...

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Benjamin Philip Levy, MD, on maintenance therapy following carboplatin, pemetrexed & pembrolizumab

Dr. Levy offers opinion on continuing pemextrexed maintenance after successful treatment of a non-small cell lung cancer (NSCLC) patient with ...

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Benjamin Philip Levy, MD, comments on the IMpower150 clinical trial in NSCLC

Dr. Levy shares key takeaways from the Impower150 study in non-small cell lung cancer (NSCLC) and whether the outcomes change ...

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Benjamin Philip Levy, MD, on options for NSCLC patients who progress on 1st line I-O & chemotherapy

Dr. Levy elaborates on some of the current treatment options for non-small cell lung cancer (NSCLC) patients who progress on ...

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Sai-Hong Ignatius Ou, MD, PhD, comments on Tumor Mutation Burden (TMB) as a biomarker in NSCLC

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Sai-Hong Ignatius Ou, MD, PhD, on pemetrexed maintenance therapy

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Sai-Hong Ignatius Ou, MD, PhD, discusses key takeaways from the IMpower150 study at ASCO 2018

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Sai-Hong Ignatius Ou, MD, PhD, comments on combo chemotherapy & immunotherapy in 2nd line NSCLC

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Sai-Hong Ignatius Ou, MD, PhD, regarding combo chemotherapy & immunotherapy in 1st line NSCLC

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Benjamin Philip Levy, MD, on Tumor Mutation Burden (TMB) as a biomarker in NSCLC

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Benjamin Philip Levy, MD, on maintenance therapy following carboplatin, pemetrexed & pembrolizumab

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Benjamin Philip Levy, MD, comments on the IMpower150 clinical trial in NSCLC

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Benjamin Philip Levy, MD, on options for NSCLC patients who progress on 1st line I-O & chemotherapy

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Benjamin Philip Levy, MD, regarding combo chemotherapy & immunotherapy in 2nd line NSCLC

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Benjamin Philip Levy, MD, discusses the practice-changing outcomes from Keynote 189

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Benjamin Philip Levy, MD, offers opinion on testing for PD-L1 expression in NSCLC

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Howard (Jack) West, MD, regarding Tumor Mutation Burden (TMB) as a biomarker for NSCLC patients

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Howard (Jack) West, MD, on maintenance therapy after carboplatin, pemetrexed & pembrolizimab

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Howard (Jack) West, MD, discusses key takeaways from the IMpower150 study in NSCLC

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Howard (Jack) West, MD, on treatment options for patients who progress on I-O & chemotherapy

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Howard (Jack) West, MD, regarding the combination of immunotherapy & chemotherapy in NSCLC

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Howard (Jack) West, MD, regarding PDL-1 expression and NSCLC

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Howard A. "Skip" Burris III, MD, FACP, FASCO, considers predictive biomarkers in NSCLC

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Mohammad Jahanzeb, MD, FACP, discusses the significance of Keynote 42 from ASCO 2018

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Mohammad Jahanzeb, MD, FACP, regarding pemetrexed maintenance therapy

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Mohammad Jahanzeb, MD, FACP, on the results of Keynote 189, PDL-1 expression and patient selection

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Edgardo S. Santos, MD, FACP, on the benefits of combination docetaxel + ramucirumab

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Edgardo S. Santos, MD, FACP, regarding pemetrexed maintenance therapy

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Edgardo S. Santos, MD, FACP, on the outcomes of Keynote 189 in metastatic NSCLC

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Edgardo S. Santos, MD, FACP, discusses exciting developments out of ASCO 2018

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Roy S. Herbst, MD, PhD, discusses the benefits of using ramucirumab plus docetaxel in 2nd line NSCLC

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Roy S. Herbst, MD, PhD, discusses drug sequencing as a result of Keynote 189 and 42 results

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Roy S. Herbst, MD, PhD, on if patient selection will change as a result of Keynote 42

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Roy S. Herbst, MD, PhD, on pemextrexed maintenance treatment

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Roy S. Herbst, MD, PhD, shares what's exciting here at ASCO 2018

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Roy S. Herbst, MD, PhD, on if Keynote 189 impacted view of PDL-1 expression and patient selection

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Joan Schiller, MD, regarding Keynote trials from ASCO 2018 & the influence on choice of therapy

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Joan Schiller, MD, considers the validity of Tumor Mutation Burden (TMB) as a biomarker

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Joan Schiller, MD, on the impact of Keynotes 189 & 42 on drug sequencing regimens

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Joan Schiller, MD, regarding the results of Keynote 42 presented at the 2018 ASCO Annual Meeting

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Joan Schiller, MD, considers the continuation of pemetrexed maintenance

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Joan Schiller, MD, offers her opinion on Keynote 189 & PDL-1 expression and patient selection

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David R. Gandara, MD, discusses drug sequencing as a result of Keynote 189 and 42 results

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David R. Gandara, MD, on what will change about patient selection as a result of Keynote 42

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David R. Gandara, MD, on continuing pemextrexed maintenance

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David R. Gandara, MD, on whether Keynote 189 impacted view of PDL-1 expression and patient selection

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David R. Gandara, MD, shares the benefits of using ramucirumab plus docetaxel in 2nd line NSCLC

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David R. Gandara, MD, discusses exciting new developments in lung cancer here at ASCO 2018

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Mohammad Jahanzeb, MD, FACP, discusses the impact of Keynote 189 & 42 on drug sequencing regimens

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Melissa Johnson, MD, on how Next Generation Sequencing is relevant to the treatment of NSCLC

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Melissa Johnson, MD, discusses combinations and the treatment of lung cancer

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Melissa Johnson, MD, on lung cancer patients that have a PD-L1 expression that is less than 1%

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Melissa Johnson, MD, on stratifying newly diagnosed lung cancer patients with the PD-L1 biomarker

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Melissa Johnson, MD, clarifies how physicians should use the PD-L1 biomarker

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Steven J. Cohen, MD, outlines the results of the Checkmate 142 study in mCRC patients

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Steven J. Cohen, MD, discusses vemurafenib and the NCCN guidelines for mCRC patients

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Steven J. Cohen, MD, provides insight into sequencing and efficacy outcomes in 2nd line mCRC

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Steven J. Cohen, MD, describes how tumor sidedness impacts treatment decisions in mCRC

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Steven J. Cohen, MD, regarding combination atezolizumab + cobimetinib in mCRC patients

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Steven J. Cohen, MD, considers the improvement in duration of therapy examined in the ReDOS study

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Steven J. Cohen, MD, on how to dose patients receiving regorafenib as a result of the ReDOS study

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Michael Soulen, MD, discusses the most compelling presentations from ASCO GI 2018

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Michael Soulen, MD, compares the possible benefits of retrospective vs. prospective trials

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Michael Soulen, MD, on the practice changing potential of data presented at his ASCO GI tumor board

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Michael Soulen, MD, tells us about significant data coming out of the tumor board at ASCO GI 2018

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Philip Philip, MD, PhD, FRCP, discusses the impact of the Checkmate 142 study on mCRC

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Philip Philip, MD, PhD, FRCP, on the implications of the LAPACT study presented at ASCO 2018

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Philip Philip, MD, PhD, FRCP, considers the impact of immunotherapy agents in pancreatic cancer

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Philip Philip, MD, PhD, FRCP, regarding key unmet needs in pancreatic ductal adenocarcinoma

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Nevena Damjanov, MD, shares the latest news in systemic therapy for advanced HCC at ASCO 2018

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Nevena Damjanov, MD, on the use of pembrolizumab in HCC patients previously treated with sorafenib

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Nevena Damjanov, MD, outlines the role of TACE with systemic therapy in HCC patients

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David Ilson, MD, PhD, considers how to assess response in gastroesophageal cancer patients

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Richard Kim, MD, offers opinion on the ReDOS study and dose escalation of regorafenib

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Scott Kopetz, MD, PhD, FACP, on the potential of binimetinib + immunotherapy in mCRC patients

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Scott Kopetz, MD, PhD, FACP, regarding molecular profile matching in trials with mCRC patients

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Scott Kopetz, MD, PhD, FACP, on the implications of the BEACON Phase 3 study in BRAF-mutant mCRC

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Jeffrey Meyerhardt, MD, MPH, on dose escalation of regorafenib as a result of the ReDOS study

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Jeffrey Meyerhardt, MD, MPH, discusses the length of adjuvant therapy for colorectal cancer patients

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Jeffrey Meyerhardt, MD, MPH, on the implications of the BEACON Phase 3 study in BRAF-mutant mCRC

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Jeffrey Meyerhardt, MD, MPH, considers the addition of vemurafenib to the NCCN guidelines for mCRC

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Nevena Damjanov, MD, discusses current treatment options and sequencing TKIs in HCC

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Nevena Damjanov, MD, considers the shortcomings of RECIST in measuring efficacy in HCC patients

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Scott Kopetz, MD, PhD, FACP, explains how nivolumab is being incorporated into mCRC treatment

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Scott Kopetz, MD, PhD, FACP, tells us about the outcomes of Checkmate 142 in mCRC patients

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Scott Kopetz, MD, PhD, FACP, considers the addition of vemurafenib to the NCCN guidelines for mCRC

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Scott Kopetz, MD, PhD, FACP, discusses the incidence of BRAF mutation in CRC patients

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Richard Kim, MD, offers analysis of the RAINFALL study in metastatic gastric & GE junction cancer

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Richard Kim, MD, discusses pembrolizumab as an effective agent in HCC management

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Richard Kim, MD, considers the effectiveness of combination sorafenib and TACE in HCC patients

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Richard Kim, MD, on the use and sequencing of TKIs in hepatocellular carcinoma (HCC)

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David Ilson, MD, PhD, discusses what can be done to improve outcomes in esophageal adenocarcinoma

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David Ilson, MD, PhD, examines the results of the RAINFALL study at ASCO GI 2018

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David Ilson, MD, PhD, on strategies for managing gastroesophageal patients after neoadjuvant therapy

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David Ilson, MD, PhD, on how we can individualize treatment of gastroesophageal cancer patients

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Howard Hochster, MD, outlines the results of the Checkmate 142 study in mCRC patients

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Howard Hochster, MD, considers patient age and the OncotypeDX recurrence score in CRC

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Andrew Zhu, MD, PhD, on the effectiveness of pembrolizumab in HCC patients treated with sorafenib

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Andrew Zhu, MD, PhD, shares thoughts on treating adjuvant hepatocellular carcinoma (HCC) today

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Laura Dawson, MD, FRCPC, on additional randomized studies of external beam radiation

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Laura Dawson, MD, FRCPC, tells us about the results of the START study

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Laura Dawson, MD, FRCPC, discusses the design of the START study in HCC

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Laura Dawson, MD, FRCPC, provides some background on hepatocellular carcinoma (HCC)

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Alan Venook, MD, outlines the role of liquid biopsy in gastrointestinal cancers

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Alan Venook, MD, considers how immunotherapy is being integrated into CRC treatment algorithms

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Alan Venook, MD, on the impact of dose escalation of regorafenib in mCRC patients

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Alan Venook, MD, discusses vemurafenib and the NCCN guidelines for mCRC patients

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Alan Venook, MD, explains how tumor sidedness affects therapeutic choice

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Khaldoun Almhanna, MD, MPH, offers opinion on the best way to manage early gastric cancer

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Khaldoun Almhanna, MD, MPH, discusses the risk factors to watch for gastroesophageal cancer

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Kenneth Wang, MD, offers opinion on approaches to treating esophageal cancer

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Kenneth Wang, MD, on managing esophageal cancer patients who have completed neoadjuvant therapy

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Kenneth Wang, MD, on how to assess response in esophageal cancer and utilize the information

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Howard Hochster, MD, elaborates on how tumor sidedness affects therapeutic choice in mCRC patients

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Howard Hochster, MD, on the ReDOS study, regorafenib, and the importance of duration of therapy

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Andrew Zhu, MD, PhD, shares the latest in systemic therapy for advanced HCC at ASCO GI 2018

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Andrew Zhu, MD, PhD, on how we diagnose and assess response in HCC patients

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Khaldoun Almhanna, MD, MPH, on surveillance and the management of gastroesophageal cancer

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Kenneth Wang, MD, considers how staging esophageal cancer has changed and improved

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Howard Hochster, MD, offers opinion on the ReDOS study and dose escalation of regorafenib