Ovarian Cancer Clinical Roundup

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(MedPage Today) Sept 23, 2020 - An immunotherapy boost failed to improve outcomes in newly diagnosed advanced ovarian cancer compared with chemotherapy and bevacizumab (Avastin), a large international trial showed.
(ICR [UK]) Sept 18, 2020 - Almost half of patients who received a targeted drug during treatment for newly diagnosed BRCA-mutated advanced ovarian cancer remain disease free after five years, a new study shows.
(Reuters) Sept 18, 2020 - Europe’s health regulator has recommended the approval of GSK’s cancer treatment Zejula as a first option to keep advanced ovarian cancer at bay in women who have responded to chemotherapy, the British drugmaker said on Friday.
(AstraZeneca) Sept 18, 2020 - Five-year data from the SOLO-1 Phase III trial is the longest follow-up analysis for any PARP inhibitor in the 1st-line maintenance setting. AstraZeneca and MSD’s Lynparza (olaparib) demonstrated a long-term progression-free survival (PFS) benefit versus placebo as a 1st-line maintenance treatment in...
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Featured Ovarian Cancer Tweets

Mario M. Leitao, Jr., MD, FACOG, FACS
leitaomd - Sep 23  And yet another example of differing RCT results! Ovarian Cancer: First-line Dose-dense Chemotherapy is Not https://t.co/7ExVlpD6XB

Shannon Westin, MD, MPH, FACOG
ShannonWestin - Sep 21  There was no difference in PFS or OS among women w/ recurrent #ovariancancer treated with nivolumab vs standard che… https://t.co/KE8g6cyeej

Shannon Westin, MD, MPH, FACOG
ShannonWestin - Sep 21  In a smaller group of patients w/ #ovariancancer + PD-L1 expression > 5%, there was an improvement in PFS with the… https://t.co/UuYrCe2wib

Pedro T. Ramirez, MD
pedroramirezMD - Sep 16  Actually for ovarian cytoreduction not even 3 RCTs is enough (EORTC, CHORUS, SCORPIO )..all showing no difference b… https://t.co/BlVHeEnbJQ

Mario M. Leitao, Jr., MD, FACOG, FACS
leitaomd - Sep 14  PARP inhibitors should not be used for all patients with ovarian cancer. Not only costly but also does have toxicit… https://t.co/91PF725XXt