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Featured Oncology News

AbbVie Announces New Undetectable Minimal Residual Disease Data from Phase 3 Relapsed/Refractory Chronic Lymphocytic Leukemia MURANO Trial of Venetoclax in Combination with Rituximab at 23rd European Hematology Association Annual Congress

(AbbVie) June 15, 2018 - AbbVie, a research-based global biopharmaceutical company, today announced the presentation of investigational data from a new analysis of undetectable minimal residual disease (uMRD) rates from the pivotal Phase 3 MURANO trial of venetoclax, a first-in-class oral B-cell lymphoma-2 (BCL-2) inhibitor, in combination with rituximab (VenR) in patients with relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL).

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Novartis Study Of Real-World Data Concludes Jakavi Is Associated With A Reduction In Risk Of Death And Dangerous Blood Clots For Patients With Rare Blood Cancer

(Novartis) June 15, 2018 – Novartis announced today results from a new comparison study showing that Jakavi® (ruxolitinib)-treated patients with polycythemia vera (PV), who were resistant or intolerant to hydroxyurea (HU), had a significantly reduced risk of thrombosis (blood clots) and death compared to PV patients who received best available therapy.

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Oncology Clinical News

Novartis Survey Uncovers Real-World Impact Of Immune Thrombocytopenia Or ITP, A Rare Blood Disease, On Patients' Quality Of Life

(Novartis) June 15, 2018 – Many patients with the rare blood disorder immune thrombocytopenia (ITP) find the disease has a negative impact on their everyday quality of life, according to interim results of a Novartis survey, called I-WISh, presented today at the 23rd Congress of the European Hematology Association (EHA) in Stockholm, Sweden (Abstract #PF654).

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Epizyme Reports Positive Updated Interim Data from Phase 2 Study of Tazemetostat in Patients With Relapsed or Refractory Follicular Lymphoma at the Congress of the European Hematology Association (EHA)

(NASDAQ) June 15, 2018 - Consistently high responses in patients with an EZH2 activating mutation; durable clinical responses and progression-free survival observed in patients with or without an EZH2 activating mutation.

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MorphoSys Presents Clinical Data with Blood Cancer Candidate MOR208 in Chronic Lymphocytic Leukemia at EHA 2018 Conference

(DigitalJournal.com) June 15, 2018 - MorphoSys AG today announced the presentation of clinical data from the exploratory phase 2 COSMOS trial. The trial evaluates MorphoSys's proprietary hemato-oncological drug candidate MOR208 in combination with the cancer drug idelalisib in patients with relapsed or refractory chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), who progressed on or were intolerant to ibrutinib therapy.

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Oncology Business and Policy News

China National Drug Administration Approves Country’s First Immuno-Oncology Agent, Opdivo (nivolumab injection), for Previously Treated Non-Small Cell Lung Cancer (NSCLC)

(BMS) June 15, 2018 - This is China’s first and only PD-1 inhibitor and is the only Immuno-Oncology (I-O) agent to demonstrate a survival benefit compared with chemotherapy, based on data from the pivotal Phase 3 CheckMate -078 trial, in which 90% of the patients enrolled were Chinese.

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NICE Rejects Adjuvant Use Of Perjeta Post-Surgery

(PharmaTimes [UK]) June 15, 2018 - The National Institute for Health and Care Excellence says adjuvant use of Roche’s breast cancer drug Perjeta in patients who have had surgery is not cost effective for the NHS.

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Broader Healthcare and Pharma News

Bluebird Bio Gene Therapies Show Promise Against Deadly Anemias

(Forbes) June 15, 2018 - Bluebird Bio's experimental gene therapy LentiGlobin is helping some patients two life-threatening forms of inherited anemia avoid blood transfusions.

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Bill To Encourage Generic-drug Development Passes A Key Hurdle

(STAT Plus) June 14, 2018 - With little fanfare and minimal debate, a key Senate committee voted Thursday to advance legislation that aims to spur the development of new generic drugs and in turn, lower drug prices.

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