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“45 is the New 50” As Age For Colorectal Cancer Screening Is Lowered


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Edit Profile | May 18, 2021

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Featured Oncology News Headlines

“45 is the New 50” As Age For Colorectal Cancer Screening Is Lowered

(Dana-Farber) May 18, 2021 - Prompted by a recent alarming rise in cases of colorectal cancer in people younger than 50, an independent expert panel has recommended that individuals of average risk for the disease begin screening exams at 45 years of age instead of the traditional 50.

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Agenus and Bristol Myers Squibb Announce Exclusive Global License for Agenus’ Anti-TIGIT Bispecific Antibody Program

(Agenus) May 18, 2021 - Bristol-Myers Squibb Company and Agenus Inc. today announced that they have entered into a definitive agreement under which Bristol Myers Squibb will be granted a global exclusive license to Agenus’ proprietary bispecific antibody program, AGEN1777, that blocks TIGIT and a second undisclosed target.

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More Targeted Cancer Prevention and Early Detection Strategies Needed in Breast Cancer Survivorship Care

(American Cancer Society) May 18, 2021 - A new study finds breast cancer survivors in general have higher risk of new cancer diagnosis compared to healthy individuals. The article, which appears in CANCER, states that compared to the general population in the United States, the risk of new cancer diagnoses among survivors was 20% higher for those with hormone receptor (HR) positive cancers and 44% higher for those with HR-negative cancers.

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Featured Episode of Leading Thoughts Series

Leading Thoughts: Lung Cancer - Episode 4

Lurbinectedin and ATLANTIS: What does the clinical data tell us about how to treat relapsed small cell lung cancer?

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Oncology Clinical News Headlines

 

Weak Immunogenicity in Patients with Cancer After First Dose of mRNA-based COVID-19 Vaccine

(ESMO) May 18, 2021 - No seroconversion found upon a single dose in elderly cancer patients and those treated with chemotherapy, a reason for not extending the period between the two injections.

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Multi-Gene Testing Could Detect More Hereditary Cancer Syndromes

(OSUCCC – James) May 10, 2021 - Up to 38.6% of people with colon cancer who have a hereditary cancer syndrome — including 6.3% of those with Lynch syndrome — could have their conditions remain undetected with current universal tumor-screening methods, and at least 7.1% of people with colorectal cancer have an identifiable inherited genetic mutation, according to new data published by scientists at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James).

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AI Predicts Lung Cancer Risk

(RSNA) May 18, 2021 - An artificial intelligence (AI) program accurately predicts the risk that lung nodules detected on screening CT will become cancerous, according to a study published in the journal Radiology.

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Spread of Breast Cancer Linked to Newly Discovered RNA Splicing Mechanism

(UCSF) May 17, 2021 - What kills most people who die from cancer is not the initial tumor. It’s the intolerable disease burden on the body that arises when tumor cells continually expand their numbers after spreading to different organs.

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Eisai Announces Real-World Data on the Effectiveness of HALAVEN® (eribulin mesylate) for the Treatment of Patients with Metastatic Breast Cancer (mBC) Published in Advances in Therapy

(Eisai) May 18, 2021 - Eisai today announced results from a real-world study assessing treatment patterns and clinical outcomes with HALAVEN® (eribulin mesylate) injection as a third-line therapy or greater in patients with metastatic breast cancer (mBC), including the triple-negative breast cancer (TNBC) subtype. These data were recently published in Advances in Therapy.

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Mustang Bio and City of Hope Announce First Patient Dosed in Phase 1 Clinical Trial of MB-101 (IL13Rα2-specific CAR T cells) to Treat Leptomeningeal Brain Tumors

(Yahoo! Finance) May 18, 2021 - Mustang Bio, Inc., a clinical-stage biopharmaceutical company focused on translating today’s medical breakthroughs in cell and gene therapies into potential cures for hematologic cancers, solid tumors and rare genetic diseases, and City of Hope, a world-renowned independent cancer research and treatment center, today announced that the first patient has been dosed in a clinical trial to establish the safety and feasibility of administering MB-101 (autologous IL13Rα2-CAR T cells) to patients with leptomeningeal brain tumors (e.g., glioblastoma, ependymoma or medulloblastoma).

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Featured Videos

Bo Gamble, considers how value & quality may vary across community oncology practices

Bo Gamble, Director of Strategic Practice Initiatives, Community Oncology Alliance, considers how the concepts of value and quality may vary across community oncology practices
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Oncology Business & Policy News Headlines

U.S. FDA Accepts Regulatory Submission for Sintilimab in Combination with Pemetrexed and Platinum Chemotherapy for the First-Line Treatment of People with Nonsquamous Non-Small Cell Lung Cancer

(Yahoo! Finance) May 18, 2021 - Innovent Biologics, Inc. and Eli Lilly and Company today jointly announced that the U.S. Food and Drug Administration (FDA) accepted for review a Biologics License Application (BLA) for sintilimab injection in combination with pemetrexed and platinum chemotherapy for the first-line treatment of people with nonsquamous non-small cell lung cancer (NSCLC).

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The Clinic by Cleveland Clinic Launches New Multidisciplinary Virtual Second Opinion Program for Brain and Prostate Cancer

(Yahoo! Finance) May 18, 2021 - The Clinic by Cleveland Clinic™, a transformative joint venture between Cleveland Clinic and Amwell® that aligns world-class clinical expertise with the power of innovative digital health technologies, announced today that its virtual second opinion solution, available to health plans, employers and consumers, will now include multidisciplinary case analysis.

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Hollings Researcher Identifies That Lack Of Insurance Is Worse Than Age In Affecting Poor Cancer Outcomes

(MUSC) May 17, 2021 - MUSC Hollings Cancer Center lung cancer researcher Gerard Silvestri, M.D., found that a lack of insurance leads to worse cancer survival than for those with Medicare, in a paper published in the May issue of Health Affairs.

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Extending Telehealth Beyond the Pandemic

(ACCCBuzz Blog) May 17, 2021 - For too many Americans—especially the elderly, the underserved, and those living in rural communities—poor access to quality cancer care is a challenge.

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Novocure Announces FDA Approval of IDE Supplement for Phase 3 Pivotal LUNAR Trial of Tumor Treating Fields in Non-Small Cell Lung Cancer

(Yahoo! Finance) May 18, 2021 - Novocure today announced the U.S. Food and Drug Administration (FDA) has approved the company’s Investigational Device Exemption (IDE) supplement, reducing the enrollment requirement for its LUNAR trial to 276 patients with 12 months follow-up.

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AffyImmune Therapeutics' AIC100 Granted Fast Track Designation for Treating Thyroid Cancer

(Yahoo! Finance) May 17, 2021 - AffyImmune Therapeutics, Inc., a clinical stage biotechnology company finding safe, effective ways to use CAR T cells against solid cancers, announced today that the US Food and Drug Administration (FDA) granted Fast Track designation to its lead compound, AIC100, for the treatment of anaplastic thyroid cancer and refractory poorly differentiated thyroid cancer. The company previously received Orphan Drug designation for AIC100.

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Imugene Licenses Cd19 Oncolytic Virus From City of Hope to Turn Car T Therapy Against Solid Tumors

(Yahoo! Finance) May 18, 2021 - Imugene enhances portfolio with novel CD19-expressing oncolytic virus from City of Hope, a comprehensive cancer center in Los Angeles, California, to be developed in combination with CD19-CAR T cell therapy.

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OBR Resources

News Story Commentary

First Person Profile: Richard Pazdur, MD

It is long past time to recognize the immeasurable contributions of a dedicated, humble, selfless a...


New Therapy Shortens Treatment For HPV-related Cance...

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Broader Healthcare & Pharma News Headlines

 

FDA Issues New COVID-19 Master Protocol Guidance

(Regulatory Focus) May 17, 2021 - A new guidance from the US Food and Drug Administration (FDA) addresses how master protocols can be used in developing drugs to treat or prevent COVID-19.

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U.S. To Send Moderna, Pfizer, Johnson & Johnson Vaccines Overseas

(NPR) May 17, 2021 - President Biden on Monday announced his intention to ship surplus doses of the coronavirus vaccine to needy nations abroad, including millions of doses of the U.S.-authorized Moderna, Pfizer and Johnson & Johnson vaccines.

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Doctors Now Must Provide Patients Their Health Data, Online and On Demand

(KHN) May 18, 2021 - Last summer, Anna Ramsey suffered a flare-up of juvenile dermatomyositis, a rare autoimmune condition, posing a terrifying prospect for the Los Angeles resident: She might have to undergo chemotherapy, further compromising her immune system during a pandemic.

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COVID-19 Vaccine Trials Underway For Kids 5 And Younger

(NPR) May 17, 2021 - Eloise LaCour clutches her dolly as a nurse takes her blood pressure, then swabs the 3-year-old's delicate arm with alcohol.

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