Archived News Headlines

We have been archiving all OBR daily news stories since March 2008. Use the box below to search our archives for specific articles and content. Please note: we do not "host" news articles on our website. When a media source removes an article from their website the link becomes inactive, and you will only be able to see the date, title, first sentence and media source that published the article.

Lung Cancer Research Foundation Announces New Research Collaboration with AstraZeneca

(LCRF) Feb 23, 2021 - The Lung Cancer Research Foundation (LCRF) today announced a collaboration with AstraZeneca to fund over $900,000 in research grants focused on understanding resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) and immune checkpoint inhibitors (ICIs), including therapeutic approaches to overcome these mechanisms, as well as biomarkers of immune-mediated adverse events.

Machine Learning Tool Can Predict Malignancy in Patients With Multiple Pulmonary Nodules

(AACR) Feb 24, 2021 - A machine learning-based tool was able to predict the risk of malignancy among patients presenting with multiple pulmonary nodules and outperformed human experts, previously validated mathematical models, and a previously established artificial intelligence tool, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

FDA Analysis Of Johnson & Johnson COVID-19 Vaccine Finds It Safe, Effective

(NPR) Feb 24, 2021 - The Food and Drug Administration released an analysis of Johnson & Johnson's COVID-19 vaccine Wednesday morning that supports its authorization for emergency use.

Theralase Launches Fifth Clinical Study Site in the US for Phase II Bladder Cancer Clinical Study

(BioSpace) Feb 24, 2021 - Theralase Technologies Inc. announced today that University of Wisconsin Health-Madison has received site Institutional Review Board approval to commence a pivotal Phase II Non-Muscle Invasive Bladder Cancer ("NMIBC") Clinical Study to enroll and treat patients with Bacillus Calmette Guerin("BCG")-Unresponsive Carcinoma In-Situ ("CIS") or who are intolerant to BCG Therapy ("Study II").

Drug Executives: Big Jump In Vaccine Supply Is Coming Soon

(Associated Press) Feb 23, 2021 - COVID-19 vaccine makers told Congress on Tuesday to expect a big jump in the delivery of doses over the coming month, and the companies insist they will be able to provide enough for most Americans to get inoculated by summer.

Androgen Cycling Shows Promise in Castration-Resistant Prostate Cancer

(MedPage Today) Feb 23, 2021 - A treatment strategy based on manipulation of testosterone levels showed promise as a potential aid for managing castration-resistant prostate cancer (CRPC), according to a randomized proof-of-principle trial.

Salarius Pharmaceuticals Initiates Expansion Stage of Phase 1/2 Clinical Trial of Seclidemstat in Patients with Ewing Sarcoma and Ewing-Related Sarcomas

(Morningstar) Feb 24, 2021 - Relapsed and refractory Ewing sarcoma patients to receive seclidemstat in combination with chemotherapy agents as second- and third-line therapy; Protocol amendment expands and improves access to addressable patient population.

Generic-Drug Labeling Strategy Likely to Survive Teva Rehearing

(Bloomberg) Feb 23, 2021 - A U.S. appeals court panel signaled that it wants to ensure generic-drug makers can continue selling low-cost copycat medicines with limited-use labels as long as they don’t actively promote newer uses discovered by brand-name companies.

AMP Survey Finds Significant Decline in Molecular Cancer Testing Due to COVID-19 Pandemic

(360Dx) Feb 23, 2021 - The Association for Molecular Pathology released preliminary survey results on Tuesday showing that molecular testing for cancer declined significantly during the COVID-19 pandemic. The "Molecular Testing for Cancer during COVID-19" survey was conducted in October and garnered 219 responses. Eighty-five percent of respondents reported that molecular testing for cancer decreased during April, May, and June of 2020 compared to 2019.

Children’s Hospitals, Pediatricians Urge Biden To Prioritize Youth Mental Health

(The Hill) Feb 24, 2021 - Children’s hospitals and pediatricians are calling on the Biden administration to prioritize children’s mental, emotional and behavioral health in addressing the COVID-19 pandemic.