Video Center


The OBR Video Center Features educational videos covering a wide range of oncology specific topics.

Ana Maria Arance Fernandez, MD, PhD, regrading the LEAP-004 clinical trial presented at ESMO 2020

Dr. Arance, Hospital Clínic de Barcelona, Barcelona, Spain, shares the design and outcomes of the LEAP-004 Phase II study investigating the combination of pembrolizumab and lenvatinib in melanoma presented at the 2020 ESMO Virtual Congress

Tags: ESMOMelanoma (includes BCC)

Published: 26 September 2020

Recent Videos: Melanoma (includes BCC)

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Ana Maria Arance Fernandez, MD, PhD, regrading the LEAP-004 clinical trial presented at ESMO 2020

Dr. Arance, Hospital Clínic de Barcelona, Barcelona, Spain, shares the design and outcomes of the LEAP-004 Phase II study investigating ...

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Ana Maria Arance Fernandez, MD, PhD, on the progress & data in melanoma coming out of ESMO 2020

Dr. Arance, Hospital Clínic de Barcelona, Barcelona, Spain, shares thoughts on the progress and data in melanoma coming out of ...

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Alexander Stratigos, MD, PhD, speculates on next steps in the development of cemiplimab in BCC

Dr. Stratigos, Director, Dermato-Oncology Center and Melanoma Unit Andreas Sygros Hospital, Professor of Dermatology, Department of Dermatology-Venereology, University of Athens ...

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Alexander Stratigos, MD, PhD, on the latest data investigating the use of cemiplimab in BCC

Dr. Stratigos, Director, Dermato-Oncology Center and Melanoma Unit Andreas Sygros Hospital, Professor of Dermatology, Department of Dermatology-Venereology, University of Athens ...

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Alexander Stratigos, MD, PhD, considers the effectiveness of hedgehog inhibitors in BCC

Dr. Stratigos, Director, Dermato-Oncology Center and Melanoma Unit Andreas Sygros Hospital, Professor of Dermatology, Department of Dermatology-Venereology, University of Athens ...

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Alexander Stratigos, MD, PhD, provides perspective on the PD-1 biomarker in BCC

Dr. Stratigos, Director, Dermato-Oncology Center and Melanoma Unit Andreas Sygros Hospital, Professor of Dermatology, Department of Dermatology-Venereology, University of Athens ...

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Danny Rischin, MD, considers whether Libtayo (cemiplimab) is a standard of care in advanced CSCC

Dr. Rischin, Director, Peter MacCallum Cancer Center, considers whether Libtayo (cemiplimab) is a standard of care in advanced cutaneous squamous ...

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Danny Rischin, MD, discusses unmet needs and how advanced CSCC was treated prior to cemiplimab

Dr. Rischin, Director, Peter MacCallum Cancer Center, discusses unmet needs and how advanced cutaneous squamous cell carcinoma was treated prior ...

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Danny Rischin, MD, shares long-term outcomes of the clinical study regarding advanced CSCC

Dr. Rischin, Director, Peter MacCallum Cancer Center, shares long-term outcomes of the clinical study investigating the PD-1 inhibitor Libtayo (cemiplimab) ...

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Ana Maria Arance Fernandez, MD, PhD, on the progress & data in melanoma coming out of ESMO 2020

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Alexander Stratigos, MD, PhD, speculates on next steps in the development of cemiplimab in BCC

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Alexander Stratigos, MD, PhD, on the latest data investigating the use of cemiplimab in BCC

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Alexander Stratigos, MD, PhD, considers the effectiveness of hedgehog inhibitors in BCC

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Alexander Stratigos, MD, PhD, provides perspective on the PD-1 biomarker in BCC

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Danny Rischin, MD, considers whether Libtayo (cemiplimab) is a standard of care in advanced CSCC

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Danny Rischin, MD, discusses unmet needs and how advanced CSCC was treated prior to cemiplimab

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Danny Rischin, MD, shares long-term outcomes of the clinical study regarding advanced CSCC

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Jason J. Luke, MD, FACP, on the most compelling data in metastatic melanoma from ESMO 2019

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Jason J. Luke, MD, FACP, on how data from ESMO 2019 may impact the treatment of melanoma

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Michael B. Atkins, MD, regarding the long-term follow up of Checkmate-004 in metastatic melanoma

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Jeffrey Weber, MD, PhD explains the importance of testing for NRAS as compared with a BRAF Biomarker

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Jeffrey Weber, MD, PhD discusses the long term side effects with immunotherapies

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Jeffrey Weber, MD, PhD explains the importance of administering ipilimumab with a PD-L1 inhibitor

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Jeffrey Weber, MD, PhD provides interpretation of the NEMO trial results

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Jeffrey Weber, MD, PhD explains the long term data from Keynote-001 study in advanced melanoma

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Eleni Efstathiou, MD, PhD, shares thoughts on the TROPHY-U-01 clinical study presented at ESMO 2020

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Eleni Efstathiou, MD, PhD, provides perspective on the IPATential150 study in mCRPC

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Eleni Efstathiou, MD, PhD, on whether genetic mutation data impacts the treatment of prostate cancer

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Eleni Efstathiou, MD, PhD, on the practice-changing potential of the PROfound study from ESMO 2020

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Eleni Efstathiou, MD, PhD, regarding patients more likely to respond to nivolumab + cabozantinib

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Eleni Efstathiou, MD, PhD, offers opinion on whether CheckMate 9ER is practice-changing

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Eleni Efstathiou, MD, PhD, discusses the CheckMate 9ER clinical trial presented at ESMO 2020

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Matthew Galsky, MD, on how studies focused on genetic mutations impact prostate cancer treatment

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Arun Azad, MBBS, PhD, FRACP, on the evolving treatment landscape of advanced prostate cancer

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Matthew Galsky, MD, discusses the practice-changing potential of the PROfound study from ESMO 2020

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Ken Kato, MD, PhD, on the role of PD-L1 biomarkers in the treatment of esophageal cancer

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Arun Azad, MBBS, PhD, FRACP, considers how recent clinical trials influence the treatment of mCRPC

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Matthew Galsky, MD, considers the implications of the IMvigor130 clinical study

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Arun Azad, MBBS, PhD, FRACP, tells us about the outcomes of the PROfound study presented at ESMO '20

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Matthew Galsky, MD, on the CheckMate-274 study in high risk, muscle-invasive urothelial carcinoma

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Ken Kato, MD, PhD, regarding the treatment of adenocarcinoma versus squamous cell carcinoma

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Arun Azad, MBBS, PhD, FRACP, shares impressions of the post-hoc analysis of the ARCHES study

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Matthew Galsky, MD, regarding the TROPHY-U-01 study presented at the 2020 ESMO Virtual Congress

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Ken Kato, MD, PhD, shares the design and outcomes of the Keynote-590 trial from ESMO 2020

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Elizabeth Mittendorf, MD, PhD, discusses the outcomes of the IMpassion-031 study

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Elizabeth Mittendorf, MD, PhD, on the implications of the IMpassion-130 and IMpassion-131 trials

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Elizabeth Mittendorf, MD, PhD, considers key takeaways from the Impassion-131 presented at ESMO 2020

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Elizabeth Mittendorf, MD, PhD, discusses the IMpassion-130 clinical trial presented at ESMO 2020

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Ana Maria Arance Fernandez, MD, PhD, on the combination of TKIs and checkpoint inhibitors

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Robert L. Coleman, MD, FACOG, FACS, regarding the antibody-drug conjugate tisotumab vedotin

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Geoffrey Y. Ku, MD, elaborates on the promising PRS-343 compound

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Robert L. Coleman, MD, FACOG, FACS, shares results of the innovaTV 204 study in cervical cancer

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Roy S. Herbst, MD, PhD, shares thoughts on the update to Keynote-024 presented at ESMO 2020

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David S. Hong, MD, regarding the Phase I clinical trial investigating sotorasib (AMG 510)

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Nicholas James, MD, PhD, offers a summary of the STAMPEDE study to date

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Geoffrey Y. Ku, MD, discusses results of the Phase I study investigating PRS-343 in GI malignancies

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Jaffer Ajani, MD, elaborates on the role of PD-L1 biomarkers in determining treatment decisions

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Robert L. Coleman, MD, FACOG, FACS, on next steps in the clinical development of tisotumab vedotin

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Roy S. Herbst, MD, PhD, elaborates on the design and outcomes of the EMPOWER-lung 1 clinical study

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David S. Hong, MD, speculates on the next steps in the development of sotorasib (AMG 510)

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Nicholas James, MD, PhD, analyzes the duration of response in Arm G of the STAMPEDE clinical trial

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Geoffrey Y. Ku, MD, provides perspective on the CheckMate-577 clinical study presented at ESMO 2020

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Robert L. Coleman, MD, FACOG, FACS, shares his impressions of the SOLO-1 update from ESMO 2020

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Roy S. Herbst, MD, PhD, tell us about the PIONeeR study presented at the 2020 ESMO Virtual Congress

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Geoffrey Y. Ku, MD, offers opinion on the practice-changing potential of the CheckMate-649 study

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Robert L. Coleman, MD, FACOG, FACS, on the role of HRD in the management of ovarian cancer

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Roy S. Herbst, MD, PhD, offers his impressions of the ADAURA trial presented at ESMO 2020

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Geoffrey Y. Ku, MD, on treating squamous cell carcinoma versus adenocarcinoma of the esophagus

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Robert L. Coleman, MD, FACOG, FACS, tells us about the negative outcomes from the IMagyn050 study

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Alex Spira, MD, PhD, FACP, on the practice-changing potential of the ADAURA study from ESMO 2020

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Alex Spira, MD, PhD, FACP, offers thoughts on the four-year follow-up to the Phase III PACIFIC trial

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Alex Spira, MD, PhD, FACP, shares thoughts on the Phase I CHRYSALIS study presented at ESMO 2020

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Alex Spira, MD, PhD, FACP, discusses the mechanism of action of amivantamab (JNJ-6372)

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Petros Grivas, MD, PhD, offers perspective on the JAVELIN Bladder 100 trial updated at ESMO 2020

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Petros Grivas, MD, PhD, summarizes the clinical progress made in prostate cancer from ESMO 2020

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Laurence Albigès, MD, PhD, on patient responses to combo nivolumab + ipilimumab in 1st line RCC

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Jaffer Ajani, MD, considers results from the CheckMate 649 study presented at ESMO 2020

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Laurence Albigès, MD, PhD, regarding the potential challenges when combining checkpoint inhibitors

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Aditya Bardia, MD, MPH, considers the practice-changing potential of the ASCENT study from ESMO 2020

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Petros Grivas, MD, PhD, discusses the COVID-19 and Cancer Consortium (CCC19) from ESMO 2020

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Jaffer Ajani, MD, shares thoughts on the CheckMate 577 study presented at ESMO 2020

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Laurence Albigès, MD, PhD, offers opinion on whether CheckMate 214 is practice-changing

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Aditya Bardia, MD, MPH, describes the outcomes from the Phase III ASCENT study from ESMO 2020

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Petros Grivas, MD, PhD, on whether the results of TROPHY-U-01 justify a larger Phase III study

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Zarnie Lwin, MBBS, FRACP, speculates on future development of combo pembrolizumab + lenvatinib

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Jaffer Ajani, MD, provides opinion on the role of I-O in treatment of esophageal & gastric cancers

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Laurence Albigès, MD, PhD, shares outcomes & updates from the CheckMate 214 study in advanced RCC

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Aditya Bardia, MD, MPH, discusses the design of newly approved sacituzumab govitecan

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Petros Grivas, MD, PhD, offers thoughts on the TROPHY-U-01 clinical study from ESMO 2020

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Zarnie Lwin, MBBS, FRACP, shares the design & outcomes of the LEAP-005 Phase II study from ESMO 2020

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Zarnie Lwin, MBBS, FRACP, on the safety and efficacy of combining TKIs with checkpoint inhibitors

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Andrew Schmidt, MD, speculates on next steps for the COVID-19 and Cancer Outcomes study (CCOS)

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Cristina Suárez, MD, on what physicians should consider when combining checkpoint inhibitors & TKIs

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Andrew Schmidt, MD, regarding the predicted surge in the number of cancer patients due to COVID-19

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Cristina Suárez, MD, on patient subtype responses to combo nivolumab + cabozantinib in 1st line RCC

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Cristina Suárez, MD, offers opinion on whether the CheckMate 9ER trial is practice-changing

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Andrew Schmidt, MD, on interventions that may help correct the disparity in cancer care disruptions

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Cristina Suárez, MD, compares the control arm of CheckMate 9ER with current 1st line RCC regimens

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Andrew Schmidt, MD, on the nature of COVID-19 cancer care disruptions among minority populations

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Cristina Suárez, MD, elaborates on the outcomes of the CheckMate 9ER study presented at ESMO 2020

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Andrew Schmidt, MD, regarding the COVID-19 and Cancer Outcomes Study (CCOS) presented at ESMO 2020

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Cristina Suárez, MD, on the promise of I-O in advanced renal cell carcinoma

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Erika Hamilton, MD, shares thoughts on tolerability in high risk early breast cancer patients

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Erika Hamilton, MD, considers the comparison between the monarchE and PALLAS clinical trials

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Giuseppe Giaccone, PhD, MD, speculates on next steps in the development of Tedopi (OSE2101)

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Erika Hamilton, MD, considers the significance of the MonarchE study & the use of abemaciclib

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Maha Hussain, MD, provides perspective on the Phase III PROfound study presented at ESMO 2020

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Giuseppe Giaccone, PhD, MD, regarding the step 1 results of the Phase III ATALANTE-1 trial in NSCLC

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Erika Hamilton, MD, regarding the Phase III monarchE trial presented at ESMO 2020

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Pasi A. Jänne, MD, PhD, offers opinion on the next steps in the development of mobocertinib

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Maha Hussain, MD, shares the design of the Phase III PROfound study in mCRPC

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Giuseppe Giaccone, PhD, MD, regarding the mechanism of action of Tedopi (OSE2101)

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Erika Hamilton, MD, on how CDK4/6 inhibitors transformed the management of metastatic breast cancer

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Pasi A. Jänne, MD, PhD, shares data from ESMO 2020 investigating mobocertinib

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Maha Hussain, MD, considers the role of homologous recombination repair in the management of mCRPC

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Giuseppe Giaccone, PhD, MD, comments on the incidence of HLA-A2 positive (NSCLC)

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Erika Hamilton, MD, on the standard of care for high-risk early HR+, HER2- breast cancer

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Pasi Jänne, MD, PhD, elaborates on EGFR exon 20 insertions in non-small cell lung cancer

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Maha Hussain, MD, regarding the evolving treatment landscape of mCRPC

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Shirish M. Gadgeel MBBS, comments on significant studies in ALK+ NSCLC from ESMO 2019

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Véronique Diéras, MD, on the optimal setting in which to receive a PARP inhibitor

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Robert L. Coleman, MD, FACOG, FACS, on takeaways from the ovarian plenary session at ESMO '19

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Amer Zeidan, MBBS, comments on the influx of investigational oral agents in myeloid malignancies

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Arndt Vogel, MD, elaborates on some of the key takeaways from the GO30140 trial

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George Sledge, MD, explains how MONARCH-2 may impact the current standard of care

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Dennis J. Slamon, MD, PhD, discusses implications from the MONALEESA-3 trial

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Nader Sanai, MD, offers perspective on the challenges in treating glioblastoma

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Christian Rolfo, MD, PhD, MBA, on the role of liquid biopsy in the treatment of lung cancer

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Ulrik Lassen, MD, PhD, on whether testing for TRK fusion is easy and reliable

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Scott Kopetz, MD, explains how BRAF mutations figure into treatment algorithms for CRC

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Stefan Kasper, MD, provides updates on the BEACON trial in BRAF-mutant CRC

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Shirish M. Gadgeel MBBS, speculates on the future of RET-altered NSCLC

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Véronique Diéras, MD, on BRCA-positive metastatic breast cancer & PARP inhibitors

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Robert L. Coleman, MD, FACOG, FACS, on the VELIA, PAOLA-1 and PRIMA studies

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Amer Zeidan, MBBS, on his study investigating onvansertib + cytarabine or decitabine in AML

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Arndt Vogel, MD, elaborates on the results of the CheckMate-459 study in HCC

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Brian Van Tine, MD, shares some of the top studies in sarcoma presented at ESMO 2019

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George Sledge, MD, shares the most relevant findings from the MONARCH-2 trial

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Dennis J. Slamon, MD, PhD, on the significance of the phase III MONALEESA-3 trial

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Deborah Shrag, MD, MPH, on which biomarkers are important in the diagnosis & management of CRC

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Nader Sanai, MD, shares details from the most promising studies in glioma presented at ESMO 2019

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Christian Rolfo, MD, PhD, MBA, on the development of RET-Fusion in NSCLC

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Ulrik Lassen, MD, PhD, discusses the incidence of TRK fusion in various tumor types

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Scott Kopetz, MD, shares updates from the BEACON trial in BRAF-mutant colorectal cancer

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Stefan Kasper, MD, explains the dosing and administration schedule of cetuximab

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Shirish M. Gadgeel MBBS, regarding the most exciting data in lung cancer from ESMO 2019

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Véronique Diéras, MD, elaborates on the BROCADE 3 study presented at ESMO 2019

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Robert L. Coleman, MD, FACOG, FACS, on how veliparib factors into ovarian cancer treatment

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Brian Van Tine, MD, considers the role of real-world outcomes in the treatment of sarcoma

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Arndt Vogel, MD, offers his opinion on pemigatinib in the management of cholangiocarcinoma

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Jason J. Luke, MD, FACP, on the role of CAR-Ts in the treatment of solid tumors

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Banu Arun, MD, regarding the optimal setting for PARP inhibitors in breast cancer treatment

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David Gershenson, MD, on considerations for maintenance therapy in ovarian cancer

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Banu Arun, MD, on PARP inhibitors in BRCA positive metastatic breast cancer

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David Gershenson, MD, tells us what's new in the treatment of rare epithelial cancers

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Banu Arun, MD, regarding veliparib in breast cancer patients with BRCA mutations

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David Gershenson, MD, elaborates on the role of MEK inhibitor trametinib in LGSC

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Arndt Vogel, MD, shares his impression of the FIGHT-202 trial in cholangiocarcinoma

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Ahmed Kaseb, MD, considers the effectiveness of bevacizumab + atezolizumab in HCC

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Brian Van Tine, MD, discusses the design of the SPEARHEAD-1 trial

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Ahmed Kaseb, MD, elaborates on the phase 1b study investigating atezolizumab + bevacizumab in HCC

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Christopher J. Hoimes, MD, considers the role of I-O in perioperative muscle-invasive bladder cancer

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Brian Van Tine, MD, on the most promising investigational agents in advanced sarcoma

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Ahmed Kaseb, MD, offers opinion on nivolumab + ipilimumab in resectable HCC

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Christopher J. Hoimes, MD, comments on the design and outcomes of KEYNOTE-866

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Joyce O’Shaughnessy, MD, elaborates on the MONALEESA-3 trial presented at ESMO 2019

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Christopher J. Hoimes, MD, regarding the EV-103 study presented at ESMO 2019

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Joyce O’Shaughnessy, MD, shares relevant findings from the MONARCH-2 trial

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Geoffrey Oxnard, MD, on the effectiveness of lorlatinib as a frontline agent in ALK+ NSCLC

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Joyce O’Shaughnessy, MD, on the role of CDK4/6 inhibitors in the management of TNBC

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Geoffrey Oxnard, MD, explains how genomic markers can guide treatment in PD-L1 positive NSCLC

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Joyce O’Shaughnessy, MD, shares results of the Impassion130 trial presented at ESMO 2019

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Suresh Ramalingam, MD, provides perspective on the PD-L1 and TMB biomarkers in lung cancer

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David Spigel, MD, on how results from the FLAURA study impact treatment selection in lung cancer

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Suresh Ramalingam, MD, offers opinion on optimal sequencing of immunotherapy in NSCLC

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Michael J. Birrer, MD, PhD, considers the benefits of various PARP inhibitors in ovarian cancer

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David Spigel, MD, tells us about the results of CheckMate-227 presented at ESMO 2019

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Suresh Ramalingam, MD, on how the FLAURA trial may impact care for EGFR-mutated NSCLC

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Marwan Fakih, MD, considers implications from the AMG 510 trial

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Michael J. Birrer, MD, PhD, regarding BRCA status in newly diagnosed ovarian cancer

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Michael J. Birrer, MD, PhD, on the role of maintenance therapy in newly diagnosed ovarian cancer

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Michael J. Birrer, MD, PhD, elaborates on the outcomes from the FORWARD I study

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Michael Birrer, MD, on the key takeaways from the ovarian plenary session in ovarian cancer at ESMO 2019

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David Spigel, MD, on the use of genomic markers like TMB to guide 1st NSCLC treatment

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Joyce O’Shaughnessy, MD, on differentiating CDK4/6 inhibitors

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Geoffrey Oxnard, MD, on the FLAURA study impacting treatment selection in EGFR mutant lung cancer

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Marwan Fakih, MD, on whether MSI-high is a “must-have” biomarker for CRC patients

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Suresh Ramalingam, MD, discusses the results of CheckMate 227 in advanced NSCLC patients

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Nader Sanai, MD, on the role of ribociclib in the management of gliomas

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Suresh Ramalingam, MD, FASCO, shares results from the FLAURA trial presented at ESMO 2019

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Marwan Fakih, MD, discusses the Phase 1 trial evaluating AMG 510 in CRC and NSCLC